Lactate/AARS1-mediated H3K18la in the modulation of ACSL4 transcription to trigger ferroptosis in myocardial ischemia reperfusion [0.03%]
乳酸/AARS1介导的H3K18la在ACSL4转录调控中的作用及其在心肌缺血再灌注诱导铁死亡中的机制研究
Dianhua Zhou,Jianfeng Ye,Zhubin Lun et al.
Dianhua Zhou et al.
Objective: Hypertension serves as a pivotal risk factor for myocardial ischemia reperfusion injury (MIRI). Reciprocally, MIRI exacerbates hypertension by inducing oxidative stress, inflammatory responses, cardiomyocyte de...
Does hydrochlorothiazide-associated hyponatremia in hypertensive individuals have a genetic origin? [0.03%]
氢氯噻嗪引起的高血压患者的低钠血症与遗传因素有关吗？
Gulsum Ozkan,Caner Celik,Hilmi Tozkir et al.
Gulsum Ozkan et al.
Objective: Hyponatremia is one of the most common electrolyte disorders in clinical practice and is frequently observed following thiazide use. Advanced age and female gender are implicated in the etiology of hydrochlorot...
Adiponectin improves the aortic dissection by inhibiting inflammatory cell infiltration and macrophage pyroptosis [0.03%]
脂联素通过抑制炎性细胞浸润和巨噬细胞焦亡改善主动脉夹层
Keng Zhong,Libo Zhao,Chengliang Cai et al.
Keng Zhong et al.
Objective: Aortic dissection (AD) is a fatal cardiovascular emergency that is predominantly induced by long-term uncontrolled hypertension. Materials and ...
Electroacupuncture for essential hypertension: Mechanistic insights, current clinical evidence, and translational challenges [0.03%]
电针治疗原发性高血压：机制洞察、现有临床证据及转化挑战
Yanfang Zhou,Simin Qin,Yihong Ma
Yanfang Zhou
Background: Essential hypertension (EH) remains a leading modifiable risk factor for cardiovascular morbidity and mortality worldwide. Electroacupuncture (EA), combining traditional acupuncture with pulsed electrical stim...
Association of intracranial atherosclerotic stenosis with 1-year cognitive impairment after acute ischemic stroke or transient ischemic attack: a nationwide prospective cohort study [0.03%]
颅内动脉粥样硬化性狭窄与急性缺血性卒中或短暂性脑缺血发作后一年内认知障碍的关系：一项全国多中心队列研究
Yanyan Cao,Ganghua Feng,Yu Zhang et al.
Yanyan Cao et al.
Background and purpose: Intracranial atherosclerotic stenosis (ICAS) is common in patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA), but its relationship with long-term cognitive impairment rema...
Frailty as a mediator of the association between hyperuricemia and stroke risk: A prospective cohort study [0.03%]
高尿酸血症与卒中风险之间关系的中介因素--前瞻性队列研究
Qingchun Song,Xiaokang Tu,Zilong Zheng et al.
Qingchun Song et al.
Background: Existing evidence on the interrelationship among hyperuricemia, physical frailty, and stroke remains limited and unclear. This study aimed to examine the associations of hyperuricemia and frailty with the inci...
Synergistic impact of nondipper heart rate and blood pressure on left ventricular hypertrophy in essential hypertension [0.03%]
非 dipping 型心率对高血压左心室肥厚的影响
Bingqing Zhou,Yuanyuan Jiang,Dongyu Hu et al.
Bingqing Zhou et al.
Background: Left ventricular hypertrophy (LVH) is a serious complication of hypertension. However, the association between the nondipper heart rate (NDHR) and the risk of LVH remains unclear. ...
From clinic to home monitoring: Diagnostic strategies and evidence landscape of white-coat uncontrolled hypertension [0.03%]
从临床到家庭监测：白大衣未控制高血压的诊断策略和证据格局
Zhongming Zheng,Zhenqiu Yu
Zhongming Zheng
White-coat Uncontrolled Hypertension (WUH) is characterized by elevated office blood pressure but normal out-of-office levels, and it has shifted from a phenomenological concept to a precision diagnosis model centered on ambulatory and home...
Comparative analysis of inflammatory and metabolic indices (HALP score, NLR, LMR, and TyG index) in healthy individuals, dipper, and non-dipper hypertensive phenotypes [0.03%]
健康人和昼夜血压节律异常的高血压患者的炎症及代谢指标（HALP评分、中性粒细胞淋巴细胞比值、淋巴细胞单核细胞比值和胰岛素抵抗TyG指数）的比较分析
Huseyin Kandemir,Caglar Alp
Huseyin Kandemir
Objective: This study aimed to compare the metabolic and inflammatory profiles of dipper and non-dipper hypertensive patients versus healthy controls, specifically evaluating the Triglyceride-glucose (TyG) index's associa...