Beyond Stiffness: Collagen Signaling in Pancreatic Cancer and Pancreas Regeneration [0.03%]
超越 stiffness：胰腺癌和胰腺再生中的胶原蛋白信号通路研究
Huocong Huang,Rolf A Brekken
Huocong Huang
This commentary highlights the article by Ruggeri et al that reports the importance of discoidin domain receptor 1 in tissue homeostasis in pancreatic injury and pancreatic ductal adenocarcinoma pathogenesis. ...
This Month in AJP [0.03%]
AJP本月回顾
The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. Copyright © 2020 Amer...
Corrections [0.03%]
更正通知书
Published Erratum
The American journal of pathology. 2020 Jul;190(7):1580. DOI:10.1016/j.ajpath.2020.05.001 2020
Correction [0.03%]
改正措施
Published Erratum
The American journal of pathology. 2020 Jul;190(7):1580. DOI:10.1016/j.ajpath.2020.05.002 2020
Tumor Necrosis Factor Receptor Associated Factor 3 Modulates Cartilage Degradation through Suppression of Interleukin 17 Signaling [0.03%]
肿瘤坏死因子受体相关因子3通过抑制白细胞介素17信号转导调节软骨降解
Guoli Hu,Ning Zhang,Jiao Li et al.
Guoli Hu et al.
Interleukin 17A (IL-17A) is critical in the pathogenesis of autoimmune diseases through driving inflammatory cascades. However, the role of IL-17 in osteoarthritis (OA) is not well understood. Tumor necrosis factor-receptor-associated facto...
High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients [0.03%]
染色体拷贝数改变和TP53突变与青年乳腺癌患者的不良预后相关
Ayla Koçak,Kerstin Heselmeyer-Haddad,Annette Lischka et al.
Ayla Koçak et al.
Prognosis in young patients with breast cancer is generally poor, yet considerable differences in clinical outcomes between individual patients exist. To understand the genetic basis of the disparate clinical courses, tumors were collected ...
A Single Amino Acid Replacement in Penicillin-Binding Protein 2X in Streptococcus pyogenes Significantly Increases Fitness on Subtherapeutic Benzylpenicillin Treatment in a Mouse Model of Necrotizing Myositis [0.03%]
苯唑西林结合蛋白PBPs的一种单个氨基酸改变可使化脓性链球菌在小鼠坏死性肌炎模型中低剂量青霉素治疗下适应性增强
Randall J Olsen,Luchang Zhu,James M Musser
Randall J Olsen
Invasive strains of Streptococcus pyogenes with significantly reduced susceptibility to β-lactam antibiotics have been recently described. These reports have caused considerable concern in the international infectious disease, medical micr...
The Unraveling: Cardiac and Musculoskeletal Defects and Their Role in Common Alzheimer Disease Morbidity and Mortality [0.03%]
错综复杂：心脏和肌肉骨骼缺陷在常见阿尔茨海默病发病和死亡中的作用
Vidyani Suryadevara,Michael Klüppel,Federica Del Monte et al.
Vidyani Suryadevara et al.
Alzheimer disease (AD) is characterized by deterioration of cognitive capabilities with an estimated 44 million individuals worldwide living with it. Beyond memory deficits, the most common AD co-morbidities include swallowing defects (musc...
CD4+ T-Cell Responses Mediate Progressive Neurodegeneration in Experimental Ischemic Retinopathy [0.03%]
实验性缺血性视网膜病理性神经退行性病变由CD4+T细胞介导
Thi Hong Khanh Vu,Huihui Chen,Li Pan et al.
Thi Hong Khanh Vu et al.
Retinal ischemic events, which result from occlusion of the ocular vasculature share similar causes as those for central nervous system stroke and are among the most common cause of acute and irreversible vision loss in elderly patients. Cu...
This Month in AJP [0.03%]
AJP本月综述
The following highlights summarize research articles that are published in the current issue of The American Journal of Pathology. Copyright © 2020 Amer...