To the Editor: Severe Necrotizing Lung Infections: Definitions and Therapeutic Indications [0.03%]
致编辑：严重坏死性肺部感染：定义和治疗指征
George Rakovich,Sebastian G Kurz
George Rakovich
Assessment and Protection of Cerebral Function in Patients with Acute Liver Failure [0.03%]
急性肝衰竭患者脑功能的评估与保护
Hao-Feng Xiong,Wan-Ting Zhang,Zhi-Jun Zhu et al.
Hao-Feng Xiong et al.
Hepatic encephalopathy (HE) is a frequent and life-threatening neurological complication of acute liver failure (ALF) encountered in the intensive care unit and remains a major determinant of short-term mortality and long-term neurological ...
Evaluating Age-Predicted Maximal Heart Rate Versus Tachycardia in SIRS Criterion [0.03%]
评估年龄预测的最大心率与SIRS标准中的心动过速
Ethan Flathers,Fang Fang,Bryan Fitzgerald et al.
Ethan Flathers et al.
BackgroundTachycardia, defined by SIRS criteria as a heart rate above 90, is commonly seen in numerous unrelated conditions, making its utility for screening in conditions like sepsis poor due to lack of sensitivity or specificity. Rather t...
A Retrospective Cohort Study Assessing the Impact of Dexmedetomidine on Prognosis in Mechanically Ventilated Sepsis Patients [0.03%]
一项回顾性队列研究：评估瑞米昔定对机械通气的重症脓毒症患者预后的影响
Zhenxing Ding,Shuai Pan,Mengzhe Wang
Zhenxing Ding
ObjectiveMechanically ventilated sepsis patients have a high mortality rate. This retrospective cohort study aimed to investigate the impact of dexmedetomidine on the clinical prognosis of mechanically ventilated sepsis patients and to anal...
SOFA-2 Versus SOFA-1 for Mortality Prediction in Infection-Triggered ICU Patients [0.03%]
SOFA-2和SOFA-1在感染触发的ICU患者死亡率预测中的对比研究
Hakkı Meriç Türkkan,Umut Özgür,Olcay Dilken et al.
Hakkı Meriç Türkkan et al.
BackgroundAccurate assessment of organ dysfunction is essential for risk stratification in critically ill patients. The traditional Sequential Organ Failure Assessment score (SOFA-1) is widely used but reflects clinical practices from the 1...
Dexmedetomidine for Reducing Mortality in Patients with Sepsis and Concomitant Heart Failure: A Retrospective Cohort Study [0.03%]
用于治疗合并心力衰竭的脓毒症患者降低死亡率：回顾性队列研究
Jinjing Mo,Hongyuan Zhang,Yusang Chen et al.
Jinjing Mo et al.
ObjectiveAlthough dexmedetomidine (DEX) is commonly used in sepsis management, its effect on prognosis in patients with concomitant heart failure (HF) remains controversial. This study aims to examine the association between DEX use and 30-...
Etomidate Versus Ketamine for Emergency Intubation in Critically Ill Patients: An Updated Meta-Analysis and Systematic Review [0.03%]
危重患者急诊插管时-etomidate与ketamine疗效和安全性的更新型meta分析及系统评价
Vítor H Andriazzi,Renato P Curcio,Michael A R A Novais et al.
Vítor H Andriazzi et al.
ObjectiveTo compare the efficacy and safety of etomidate versus ketamine as induction agents for rapid sequence intubation in critically ill adults, focusing on 28-day mortality and post-intubation hypotension.Data SourcesPubMed, Embase, an...
Lactate-Associated Gene Signatures as Predictors: A Comprehensive Analysis of Immune Profiles in Sepsis [0.03%]
乳酸相关基因特征作为预测因子：脓毒症免疫谱系的全面分析
Lei Yan,Yi Han,Chaoyang Tong
Lei Yan
BackgroundSepsis is a complex disorder characterized by a dysregulated immune response to infection. Elevated lactic acid levels and lactylation modification may induce changes in gene expression and immune cell infiltration in sepsis.Metho...
Association Between Attending Physician Transition Days and Liberation from Mechanical Ventilation in the Intensive Care Unit [0.03%]
主治医师交接班次数与重症监护室撤离机械通气的关系
Suraj Nagaraj,Ari Moskowitz,Talya Lisker et al.
Suraj Nagaraj et al.
IntroductionTransitions of care among ICU physicians have been shown to negatively affect care processes and could impact clinical outcomes. Liberation from mechanical ventilation is a judgment-based decision and may be delayed when continu...
Variability in Vasoactive Medication use Across Pediatric Intensive Care Units: A PICU Data Collaborative Study, 2010-2022 [0.03%]
儿科重症监护病房血管活性药物使用的变异：2010-2022年PICU数据协作研究结果
Stephanie R Brown,Julia A Heneghan,Colleen Badke et al.
Stephanie R Brown et al.
ObjectiveUse of vasoactive medications is common in pediatric intensive care units (ICUs), however evidence to guide medication selection is limited likely resulting in practice variation. Our objective was to describe the use of vasoactive...