Neuromodulation of Pancreatic Lymph Nodes as a Therapy for Type 1 Diabetes: An Anatomical Study on the Presence of a Neuro-Immune Link in Human Pancreatic Lymph Nodes and Potential Sites for Electrical Stimulation [0.03%]
人胰腺淋巴结中神经免疫联系的解剖学研究及其电刺激潜在部位探究以用于自身免疫性糖尿病的神经调节治疗研究
Dyonne A M Koopmans-Lotgerink Bruinenberg,Claire Mackaaij,Eric Irwin et al.
Dyonne A M Koopmans-Lotgerink Bruinenberg et al.
Objectives: Experimental studies in nonobese diabetic mice show that electrical stimulation of sympathetic nerves innervating pancreatic lymph nodes (LNs) reduces T cell activation through β-2 adrenergic signaling and li...
Phase 1 Open-Label Pilot Trial of H4 Deep Repetitive Transcranial Magnetic Stimulation for Adults With Moderate-to-Severe Cannabis Use Disorder [0.03%]
高强度重复经颅磁刺激治疗中重度大麻使用障碍患者的I期开放性试点试验
James MacKillop,Carly McIntyre-Wood,Emily Vandehei et al.
James MacKillop et al.
Objectives: Cannabis use disorder (CUD) is a significant public health problem and no medical treatments have received regulatory approval to date. Deep repetitive transcranial magnetic stimulation (dTMS) provides brief p...
Thalamic Neurostimulation and Effects on Movement Consolidation in Essential Tremor [0.03%]
丘脑神经刺激对特发性震颤运动巩固的影响
Joongsuk J Kim,Stefan Delmas,Yoon Jin Choi et al.
Joongsuk J Kim et al.
Objectives: Deep brain stimulation (DBS) of the ventralis intermedius nucleus of the thalamus (VIM DBS) effectively suppresses upper limb tremor in the setting of essential tremor (ET); however, its effect on motor learni...
Legal and Ethical Considerations for Clinical Research in Neuromodulation in the European Union: The Chimaera Checklist [0.03%]
欧盟神经调节临床研究的法律和伦理考量： Chimæra清单
Audrey Van Scharen,Lisa Goudman,Kaare Meier et al.
Audrey Van Scharen et al.
Introduction: During the last century, many ethics codes have emerged, sometimes embedding legally binding instruments, sometimes encoding good clinical practice for the first time. Apart from the general ethical consider...
Ethical Guidance for Investigational Implantable Neural Device Studies: Recommendations for Researchers and Research Ethics Committees [0.03%]
神经调控研究中的伦理问题——给研究者和伦理审查委员会的建议
Odile C van Stuijvenberg,Katherine C Bassil,Cecile C de Vos et al.
Odile C van Stuijvenberg et al.
Objectives: Clinical studies of implantable neural devices raise unique ethical and legal challenges owing to the distinctive nature of these technologies and their research contexts. Persistent issues such as inadequate ...
Analgesic Effects of Novel Spinal Cord Stimulation Waveforms in Rats With Painful Tibial Nerve Injury [0.03%]
新型脊髓刺激波形对胫神经损伤大鼠的镇痛作用
Yin Feng,Dongman Chao,Quinn Hogan et al.
Yin Feng et al.
Objectives: Neuropathic pain is associated with hyperexcitability of spinal cord dorsal horn neurons. Spinal cord stimulation (SCS) can reduce this hyperexcitability and provide analgesia. We evaluated the effects of two ...
Electrophysiologic Characteristics of Epidural Spinal Signals in Preclinical Models of Spinal Cord Stimulation [0.03%]
脊髓刺激的非临床模型中硬膜外脊髓信号的电生理特征
Kimberley Ladner,Eline M Versantvoort,Marjolein E G Thijssen et al.
Kimberley Ladner et al.
Objectives: Epidural stimulation of the spinal cord evokes distinct electrophysiologic responses that can be recorded epidurally. Here, we characterized evoked compound action potentials (ECAPs), doublets (secondary or te...
Health Care Providers' Opinions on Decision-Making During the Spinal Cord Stimulation Journey: An Online Survey [0.03%]
脊髓刺激治疗过程中的决策意见：一项在线调查
Lisa Goudman,Cormac Mullins,Julie G Pilitsis et al.
Lisa Goudman et al.
Introduction: The field of spinal cord stimulation (SCS) is characterized by the availability of multiple stimulation paradigms and device options, yet limited evidence exists on ways health care providers make decisions ...
Transcranial Photobiomodulation for Neuromodulation of Brain Disorders: A Perspective [0.03%]
颅内光生物调节在神经调控脑障碍方面的作用：一种新视角
Dirk De Ridder,Michael R Hamblin,Sven Vanneste
Dirk De Ridder
Introduction: Photobiomodulation (PBM) uses light to modulate biological activity. Because red and near-infrared wavelengths penetrate the skin and skull, PBM can be applied transcranially (tPBM) to noninvasively modulate...
Repeated Electrical Vestibular Nerve Stimulation Reduces Anxiety in People With Moderate-to-Severe Anxiety: A Randomized, Sham-Controlled Trial: The Modius Anxiety Study [0.03%]
重复电耳石神经刺激可减轻中度至重度焦虑患者的焦虑症状：一项随机对照试验：Modius焦虑研究
Grace Curry,Shu-Dong Zhang,Liadhan McAnena et al.
Grace Curry et al.
Background: Generalized anxiety disorder (GAD) affects approximately 4% of the global population. Current treatment methods, for example, pharmacology and psychotherapy, are insufficient owing to side effects and a lack o...