Neuromodulation of Pancreatic Lymph Nodes as a Therapy for Type 1 Diabetes: An Anatomical Study on the Presence of a Neuro-Immune Link in Human Pancreatic Lymph Nodes and Potential Sites for Electrical Stimulation
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Objectives: Experimental studies in nonobese diabetic mice show that electrical stimulation of sympathetic nerves innervating pancreatic lymph nodes (LNs) reduces T cell activation through β-2 adrenergic signaling and limits fur... ...