Mark A Silveria,Godfred Siaw Kumi,Michael S Chapman
Mark A Silveria
Early evidence of the efficacy of TCR-T therapy targeting the G12V mutation in patients with advanced pancreatic cancer [0.03%]
针对晚期胰腺癌G12V突变的TCR-T治疗有效性的早期证据
Hong-Ming Hu,Yu Han,Yuhong Li
Hong-Ming Hu
Promises of co-stimulatory inhibition for durable and repeatable AAV gene therapy [0.03%]
共刺激抑制的承诺：使AAV基因治疗持久且可重复
Klaudia Kuranda,David Alexandre Gross,Giuseppe Ronzitti
Klaudia Kuranda
Gene delivery for cerebral neurodegenerative disorders - current advancements and limitations [0.03%]
基因输送在脑神经退行性疾病中的应用-当前进展和局限性
Kunal Dayma,Arun Upadhyay
Kunal Dayma
Gene delivery for neurodegenerative cerebral disorders faces formidable structural and practical challenges. The blood-brain, blood- cerebrospinal fluid (CSF), and arachnoid barriers tightly regulate molecular traffic, restrict paracellular...
Extracellular vesicles from steatotic hepatocytes promote endothelial dysfunction and atherogenesis via miR-30b-5p/ELOVL5 axis [0.03%]
泡沫肝细胞源性外泌体通过miR-30b-5p/ELOVL5轴促进内皮功能障碍和动脉粥样硬化形成
Marie Rhee,Joonyub Lee,Cheol Woon Jung et al.
Marie Rhee et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly recognized as an independent risk factor for cardiovascular disease (CVD), yet the underlying molecular pathways mediating liver-to-vasculature communication r...
A novel cystic fibrosis-mimetic Pseudomonas auxotrophic vaccine is protective in vivo and is associated with Th17 and IgA mucosal immunity [0.03%]
一种新的模仿囊性纤维化假单胞菌色氨酸营养缺陷型疫苗可使小鼠获得免疫保护并伴随Th17和IgA粘膜免疫反应的产生
Youssouf Sereme,Bérengère Villeret,Ségolène Caboche et al.
Youssouf Sereme et al.
Pseudomonas aeruginosa (P.a) is a Gram-negative opportunistic pathogen that poses a major global health threat, particularly in immunocompromised individuals, patients with cystic fibrosis, and those with burn injuries or ventilator-associa...
eTnpBc and eTnpBe: Next-generation TnpBs for eukaryotic genome editing [0.03%]
下一代的TnpB（eTnpBc和eTnpBe）用于真核生物基因组编辑
Mahnoor Jamil,Ambreen Zahra,Sultan Habibullah Khan et al.
Mahnoor Jamil et al.