Implementation and Audit of Mainstream Genetic Testing Within a High-Volume UK Breast Unit for Pathogenic Variations Associated With Breast Cancer Using the R208 and R444.1 National Test Directory Criterion [0.03%]
在英国高量乳腺科中使用R208和R444.1国家检验目录标准实施和审核主流的基因检测以确定与乳腺癌相关的致病突变
Soraya Conroy,Emma Keane,Bushra Rehman et al.
Soraya Conroy et al.
Introduction: It is estimated that 5%-10% of patients who develop breast cancer have a causative inherited pathogenic or likely pathogenic variant (P/LP variant). In 2020, the UK National Test Directory published criteria...
Modified Nipple Correction Surgery Combined With Debridement for Refractory Nonpuerperal Mastitis: A Clinical Study [0.03%]
改良乳头矫正术联合清创治疗难治性非哺乳期乳腺炎临床研究
Bing Wang,Jiachen Xu,Yue Zhou et al.
Bing Wang et al.
Objective: In refractory nonpuerperal mastitis, the treatment for fistulas requires surgeries or techniques that not only remove the lesion but also correct the inverted nipple. To improve the stability of nipple correcti...
Serum IL2Rα as a Diagnostic Biomarker and Its Functional Interplay With IL-2 in Breast Cancer [0.03%]
血清IL2Rα作为诊断生物标志物及其与乳腺癌中IL-2的功能相互作用
Wei Wang,Jun Liu,Yun Wei et al.
Wei Wang et al.
Background: Breast cancer is a leading female malignancy, with chronic inflammation driving progression. The IL-2/IL-2R axis regulates immunity, but IL2RA's role in breast cancer (expression, diagnostic/prognostic value, ...
Pivotal Factors in Breast Cancer Molecular Subtypes Apoptosis Induction by ELF-EMF; Ki-67, ROS Level, HER-2, and SODs [0.03%]
乳腺癌分子亚型的电磁场诱导凋亡的关键因素；Ki-67、ROS水平、HER-2及SODs的影响
Mohadeseh Shayeghan,Fatemeh Shahriari,Fatemeh Afroughi et al.
Mohadeseh Shayeghan et al.
Background: Although increasing research has shown that extremely low-frequency electromagnetic fields (ELF-EMFs) specifically trigger PCD through the elevation of ROS levels in cancer cells, there is no adequate evidence...
Impact of Neoadjuvant Immunochemotherapy on Surgical Outcomes in Management of Early Triple-Negative Breast Cancer [0.03%]
新辅助免疫化疗在早期三阴性乳腺癌治疗中的手术结局影响研究
Tamasine Khadrouche,Mathilde Morisseau,Gabrielle Selmes et al.
Tamasine Khadrouche et al.
Background: Triple-negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. Neoadjuvant immunochemotherapy (NAIC) combining chemotherapy and pembrolizumab is now standard for Stage II-III TNBC. This stu...
Complications, Functional Recovery, and Quality of Life in Breast Cancer Patients Undergoing Axillary Surgery [0.03%]
腋窝手术乳腺癌患者的并发症、功能恢复和生活质量评估
Monica Pellegrino,Francesco Ioppolo,Monia Ranalli et al.
Monica Pellegrino et al.
Background: Survivorship considerations have gained increasing importance in patients with early breast cancer. Every surgical procedure poses a risk of complications and a potential negative impact on patient-reported ou...
Circulating Plasma Circular RNAs hsa_circ_0001785 and hsa_circ_0079876 as Promising Noninvasive Diagnostic Biomarkers for Breast Cancer: A Case-Control Study [0.03%]
血浆循环环状RNA hsa_circ_0001785和hsa_circ_0079876作为乳腺癌非侵入性诊断生物标志物的潜力：病例对照研究
Amirhossein Sangi Nasab Lahijan,Sepideh Abdollahi,Seyed Rohollah Miri et al.
Amirhossein Sangi Nasab Lahijan et al.
Background and aims: Breast cancer (BC) is a major health concern for women, with early diagnosis essential for better health outcomes such as survival. While mammography is the gold standard screening tool, it is not wit...
Systematic Review and Meta-Analysis: Association Between Circulating and Tissue Levels of Selenium and Zinc and Breast Cancer Risk [0.03%]
系统回顾和荟萃分析：硒和锌的循环及组织水平与乳腺癌风险的关系
Adrienne Pratti Lucarelli,Maria Marta Martins,Mariana Mie Teruya et al.
Adrienne Pratti Lucarelli et al.
Background: Selenium (Se) and zinc (Zn) are essential micronutrients that play roles in antioxidant defense and the regulation of cell proliferation. Increasing evidence suggests that disturbances in trace element balance...
Real-World Practice Patterns in Diagnosis and First-Line Treatment in Metastatic Breast Cancer [0.03%]
转移性乳腺癌的诊断和一线治疗的实际世界实践模式
Poorni M Manohar,Veena Shankaran,Nancy E Davidson et al.
Poorni M Manohar et al.
Intro: Divergence from national guidelines and variations in practice patterns impact care and outcomes in patients with metastatic breast cancer (MBC). We sought to assess the quality of care in the diagnosis and treatme...
Factors Associated With Preoperative Radiological Tumor Size Underestimation in Clinical T1-2 Breast Cancer Patients [0.03%]
临床T1-2期乳腺癌患者术前影像检查低估肿瘤体积的影响因素分析
Jungbin Kim,Yujin Lee,Sam-Youl Yoon et al.
Jungbin Kim et al.
Background: Accurate preoperative tumor size measurement is essential for determining optimal surgical margins in breast cancer patients. Thus, this study aimed to evaluate the factors associated with preoperative radiolo...