Daniel Foran,Kenneth Chan,Charalambos Antoniades
Daniel Foran
Perivascular adipose tissue (PVAT) is a metabolically active tissue that influences vascular function through paracrine signaling of adipokines. Pathologically altered PVAT is associated with proinflammatory, pro-oxidative, and proatherogen...
Nobuaki Suzuki,Atsuo Suzuki,Shogo Tamura et al.
Nobuaki Suzuki et al.
Background: Antithrombin resistance (ATR) is a congenital thrombotic predisposition caused by abnormal prothrombin (FII). Abnormal FII with ATR characteristics, when converted to thrombin (FIIa), shows a reduced affinity ...
Zhaoning Wang,Peiheng Gan
Zhaoning Wang
Enhancers are regulatory DNA sequences that increase the transcription of a target gene when bound by transcription factors. Decades of research endeavors have shed light on the crucial roles of enhancers in cardiovascular development and d...
Clémence Maupu,Garance Ennesser,Céline Baron-Menguy et al.
Clémence Maupu et al.
Arterial dilation can lead to aneurysm formation, most commonly affecting the aorta and intracranial arteries. Platelets are now recognized as key mediators of vascular inflammation and remodeling, contributing to the initiation and progres...
Association of Coronary Vasculitis Sequelae With Atherosclerosis in Adults With a History of Kawasaki Disease: Autopsy Pathological Findings [0.03%]
川崎病史成人冠状动脉血管炎后遗症与动脉粥样硬化的关联性：尸检病理结果分析
Yuki Yokouchi,Nanae Asakawa,Wakana Sato et al.
Yuki Yokouchi et al.
Background: In Kawasaki disease (KD), coronary arteritis occurring in infancy can lead to long-term sequelae, such as luminal dilatation, stenosis, intimal thickening, and calcification. However, the long-term evolution o...
Clinical and Molecular Differences of Hypertensive Disorders During Pregnancy [0.03%]
妊娠期高血压疾病的临床和分子学差异
Mariko Horii,Robert Morey,Jennifer N Chousal et al.
Mariko Horii et al.
Background: Hypertensive disorders of pregnancy (HDP) comprise a spectrum of 4 subtypes: chronic hypertension (cHTN), gestational hypertension (gHTN), preeclampsia, and superimposed preeclampsia (siPE). Although often cha...
NAT10-Mediated ac4C-Modification Exacerbates Ferroptosis by Stabilizing HMOX1 in Deep Vein Thrombosis [0.03%]
NAT10介导的ac4C修饰通过稳定HMOX1促进深静脉血栓形成铁死亡
Yunhong Zhang,Zhen Zhang,Xinkui Liu et al.
Yunhong Zhang et al.
Background: Deep vein thrombosis (DVT) is a prevalent peripheral vascular disorder associated with abnormal epigenetic processes and altered gene expression in endothelial cells. Accumulating evidence has demonstrated tha...
Nonhematopoietic MicroRNA-26b-/- Augments Atherosclerosis Development by Increasing Endothelial Inflammation and Leukocyte Adhesion [0.03%]
非造血miR-26b-/-通过增加内皮炎症和白细胞粘附促进动脉粥样硬化的发展
Linsey J F Peters,Kiril Bidzhekov,Remco T A Megens et al.
Linsey J F Peters et al.
Background: Atherosclerosis is a leading cause of cardiovascular diseases, and microRNA-26b (miR-26b) has emerged as a significant regulator in its development. This study investigates the role of nonhematopoietic miR-26b...
Julio Fernandez-Mendoza
Julio Fernandez-Mendoza
About 10% to 15% of the adult population reports frequent, chronic insomnia symptoms of difficulty initiating or maintaining sleep associated with daytime impairment (ie, insomnia disorder). An additional 30% to 40% report insomnia symptoms...