Chou Chou,Hasina Outtz Reed
Chou Chou
The lung lymphatics are formed from lymphatic endothelial cells and play a pivotal role in lung fluid homeostasis and immune trafficking. Though blood vascular function in the lung has long been an area of active investigation, many aspects...
Imaging Findings Associated With Socioenvironmental Exposures Inform Mechanisms of Cardiovascular Disease [0.03%]
社会环境暴露的心血管疾病影像表型及其机制研究
Shady Abohashem,Fatima Saeed,Thomas Münzel et al.
Shady Abohashem et al.
Cardiovascular disease remains the leading cause of mortality worldwide, driven by risk factors that range from traditional (eg, hypertension, hyperlipidemia) to less recognized socioenvironmental contributors. These broader exposures inclu...
Flow-Sensitive HEG1 Controls eNOS Activity to Prevent Endothelial Dysfunction, Hypertension, and Atherosclerosis [0.03%]
血流敏感HEG1调控eNOS活性防止内皮功能障碍、高血压和动脉粥样硬化
Michael D Clark,Yerin Kim,Cesar A Romero et al.
Michael D Clark et al.
68Ga-DOTATATE Measurements Predict Progression of Aortic Valve Calcification in Humans [0.03%]
68镓-DOTATATE测定可预测人类主动脉瓣钙化的发展
Wesam Aldosoky,Shady Abohashem,Guillaume Goudot et al.
Wesam Aldosoky et al.
Background: Inflammation potentiates aortic valve calcification (AVC). Gallium dodecane tetraacetic acid-Tyr3-octreotate (68Ga-DOTATATE), a positron emission tomography tracer that binds to somatostatin receptors, provide...
Atf3 Deficiency Promotes Mesodermal Commitment and Enhances Endothelial Differentiation in Embryonic Stem Cells [0.03%]
ATF3缺失可促进小鼠胚胎干细胞向中胚层分化并增强其向内皮细胞分化能力
Zongyue Jiang,Lide Su,Cuiting Chen et al.
Zongyue Jiang et al.
Background: Ischemic diseases have become a major threat to global health, with endothelial cell (EC) damage closely associated with their pathogenesis and progression. Cell therapies targeting endothelial repair have thu...
Pharmacological Inhibition of Ferroptosis Attenuates Experimental Abdominal Aortic Aneurysm Formation [0.03%]
药理学上铁死亡的抑制可减轻实验性腹主动脉瘤的形成
Jonathan R Krebs,Paolo Bellotti,Walker Ueland et al.
Jonathan R Krebs et al.
Background: The pathogenesis of abdominal aortic aneurysm (AAA) formation involves vascular inflammation, thrombosis formation, and programmed cell death, leading to aortic remodeling. In this study, we deciphered the rol...
Influence of Weight Loss and Weight Regain on Adipose Tissue Inflammation [0.03%]
体重减轻和体重反弹对脂肪组织炎症的影响
Lourdes Caceres,Aleepta Guha Ray,Margo P Emont et al.
Lourdes Caceres et al.
The global rise in obesity underscores the urgent need for effective long-term weight-management strategies. Weight loss (WL) is extremely beneficial in combating obesity complications, justifying the great success of recent WL medications....
Lei Zheng,Zhenxi Zhang,Yutong Liu et al.
Lei Zheng et al.
Background: Low wall shear stress (WSS) at arterial bifurcations and curves damages endothelial cells, promoting the development of atherosclerosis. Although the accumulation of iron in plaques has been observed, the mech...
Jenny E Kanter,Tomas Vaisar
Jenny E Kanter