Correction to: CCM3 Loss-Induced Lymphatic Defect Is Mediated by the Augmented VEGFR3-ERK1/2 Signaling [0.03%]
Correction to: CCM3丢失引起的淋巴管缺陷由VEGFR3-ERK1/2信号通路增强介导
Lingfeng Qin,Haifeng Zhang,Busu Li et al.
Lingfeng Qin et al.
Correction to: Endothelial-Specific Expression of Mitochondrial Thioredoxin Promotes Ischemia-Mediated Arteriogenesis and Angiogenesis [0.03%]
endothelial特异性的线粒体硫氧还蛋白表达促进缺血介导的动脉生成和新生血管化校正通知
Shengchuan Dai,Yun He,Haifeng Zhang et al.
Shengchuan Dai et al.
GRK2 Orchestrates VSMC Phenotypic Modulation via DNMT1-Mediated DNA Methylation Reprogramming [0.03%]
GRK2通过DNMT1介导的DNA甲基化重构调控血管平滑肌细胞表型转换
Chao-Hua Kong,Yue Sun,Li-da Wu et al.
Chao-Hua Kong et al.
Background: Vascular smooth muscle cell (VSMC) phenotypic modulation is responsible for the pathogenesis of hyper-muscularized arterial diseases. Recent studies have highlighted the critical role of epigenetic regulation ...
SUV39H1 Regulates KLF4 and Chromatin Remodeling in Smooth Muscle Cell Phenotypic Plasticity [0.03%]
SUV39H1在平滑肌细胞表型可塑性中调控KLF4和染色质重塑
Payel Chatterjee,Raja Chakraborty,Ashley J Sizer et al.
Payel Chatterjee et al.
Background: Reversible DNA methylation contributes to vascular smooth muscle cell (VSMC) phenotypic plasticity. This plasticity contributes to vascular growth and remodeling but also underlies pathologies, including intim...
TGF-β1 Promotes Angiogenesis via Endothelial-to-Mesenchymal Transition in Infantile Hemangioma [0.03%]
TGF-β1通过内皮细胞到间充质细胞的转化促进婴幼儿血管瘤的血管生成
Xue Gong,Tong Qiu,Jiangyuan Zhou et al.
Xue Gong et al.
Background: Infantile hemangioma (IH) is the most common benign tumor in infancy and severely affects aesthetics and function. Hemangioma-derived endothelial cells (HemECs) are the main cellular component of IH and contri...
CXCL4-Induced PBMCs Modulate Vascular Extracellular Matrix via Wnt5a-Dependent Matrix Metalloproteinase-7 and Calcifying Extracellular Vesicle Release [0.03%]
CXCL4诱导的PBMC通过Wnt5a依赖性基质金属蛋白酶-7和钙化细胞外囊泡释放调节血管外基质
Jona B Krohn,Laurine Kristin Sprehe,Florian Sicklinger et al.
Jona B Krohn et al.
Background: The role of macrophage heterogeneity has become increasingly well-recognized in the study of vascular inflammatory responses. The CXCL4 (chemokine [C-X-C motif] ligand 4)-induced monocyte/macrophage phenotype ...
Heparanase 2 Modulates Vascular Permeability via Heparan Sulfate-Dependent Growth Factor Signaling [0.03%]
肝素酶2通过依赖肝素硫酸盐的生长因子信号调节血管通透性
Yannic Becker,Sergey Tkachuk,Anne Jörns et al.
Yannic Becker et al.
Background: Vessel-lining endothelial cells (ECs) rely on heparan sulfate (HS) proteoglycans to regulate vascular permeability and to maintain vascular homeostasis. Hpa2 (heparanase 2) is a little-known, nonenzymatic, HS-...
Directly Measuring Atherogenic Lipoprotein Kinetics in Zebrafish With the Photoconvertible LipoTimer Reporter [0.03%]
利用光转化LipoTimer报告基因直接测量斑马鱼致动脉粥样硬化脂蛋白动力学
Tabea O C Moll,Julia G Kiefer,Mackenzie L Klemek et al.
Tabea O C Moll et al.
Background: Lipoprotein kinetics are a crucial factor in understanding lipoprotein metabolism because a prolonged time in circulation can contribute to the atherogenic character of B-lps (ApoB-containing lipoproteins). ...
Spleen Tyrosine Kinase Inhibition Mitigates Hemin-Induced Thromboinflammation in an Organ-Specific Manner in Sickle Cell Mice [0.03%]
脾酪氨酸激酶抑制以器官特异性方式缓解镰状细胞小鼠注射血红素引起的促凝血炎症反应
Juma El-Awaisi,Gina Perrella,Nicolas Mayor et al.
Juma El-Awaisi et al.
Background: Sickle cell disease (SCD) is a challenging genetic disorder characterized by hemolytic anemia, vaso-occlusive crises (VOC), and progressive organ damage. Despite its severity, effective treatments are limited....
Oxidized Phospholipids on Apo B100, Platelet Activation and Reactivity, and Long-Term Cardiovascular Outcomes [0.03%]
氧化磷脂结合载脂蛋白B100与血小板活化、反应性及长期心血管结局的关系
Sotirios Tsimikas,Alexander Kille,Klaus Kaier et al.
Sotirios Tsimikas et al.
Background: OxPL-apoB (oxidized phospholipids [OxPL] on apo B100), which include OxPL present on Lp(a) (lipoprotein [a]), are associated with higher cardiovascular risk. Experimental studies suggest that OxPL may influenc...