Hongbo Dong,Yan Li,Minjun Li et al.
Hongbo Dong et al.
Background: Arterial elasticity, noninvasively assessed by carotid-femoral pulse wave velocity (cfPWV), is an important determinant of cardiovascular health, yet reference values are lacking for Chinese youth. Moreover, t...
Omaveloxolone Driven NRF2 Activation as a Novel Therapeutic Strategy for Pulmonary Hypertension [0.03%]
NRF2激活的Omaveloxolone作为肺动脉高压的新疗法策略
Chuangjia Huang,June Bai,Ang Luo et al.
Chuangjia Huang et al.
Background: Pulmonary arterial hypertension is a progressive and life-threatening disorder characterized by elevated pulmonary arterial pressure, right ventricular hypertrophy, and eventual right heart failure. Omaveloxol...
Renal Denervation Modulates Hypothalamic Neuroinflammation via P2X7R/PI3K/Akt [0.03%]
肾交感神经消融通过P2X7受体调节下丘脑神经炎症_pi3k/akt依赖性机制
Wei Liang,Qian Liu,Qiongying Wang et al.
Wei Liang et al.
Background: Hypertension remains the leading global contributor to cardiovascular mortality. Although renal denervation (RDN) has demonstrated efficacy, the central neurobiological mechanisms sustaining its sympathoinhibi...
Functional Data Analysis of Wearable Devices Reveals Subtle Time-Varying Differences of Sleep Efficiency on 24-Hour Blood Pressure Dynamics in People With HIV [0.03%]
基于可穿戴设备的功能数据分析揭示了HIV患者的睡眠效率在24小时血压动力学中的微妙的时间差异性不同
Sara Venkatraman,Myung Hee Lee,Anthony Etyang et al.
Sara Venkatraman et al.
Clinical Modifiers of Salt Sensitivity: A Metaregression and Risk Translation Study [0.03%]
盐敏感性的临床影响因素：一项元回归和风险转化研究
Szu-Han Chen,Chih-Yu Yeh,Yu-Pan Chiang-Lin et al.
Szu-Han Chen et al.
Background: Hypertension guidelines generally recommend uniform sodium restriction although determinants of salt sensitivity, or sodium-blood pressure responsiveness, remain incompletely quantified. We estimated the popul...
2025 Donald Seldin Lecture: Leveraging Diverse Population Genomics and Multiomics Integration for Gene Discovery of Cardiovascular and Kidney Diseases [0.03%]
2025唐纳德·塞尔丁讲座：利用多样化的群体基因组学和多组学整合进行心血管和肾脏疾病基因发现
Andrea R V R Horimoto,Nora Franceschini
Andrea R V R Horimoto
This review discusses the implications of frameworks leveraging genetic admixture and multiomics data for advancing gene discovery in cardiovascular and kidney disease research. By broadening gene discovery efforts to additional populations...
Primary Aldosteronism Medical Treatment Outcomes (PAMO) Beyond 12 Months [0.03%]
醛固酮可治性 primary aldosteronism 超过 12 个月的医疗治疗效果（PAMO）
Jun Yang,Jessica Goi,Jacopo Burrello et al.
Jun Yang et al.
Background: Primary aldosteronism (PA) is a common and treatable cause of hypertension, yet data on the durability of medical treatment response beyond the first year are limited. Using the PA medical treatment outcomes f...
Fibroblast S1PR2 Amplifies NLRP3 Inflammasome Activation Under Pressure Overload [0.03%]
压力超负荷下成纤维细胞S1PR2放大NLRP3炎性小体活化
Caixia Zhou,Zhihao Liu,Zhiru Wang et al.
Caixia Zhou et al.
Background: Although NLRP3 (NOD-like receptor family pyrin domain containing 3) inflammasome activation has been implicated in pressure overload-induced cardiac hypertrophy, inflammation, and heart failure, prior studies ...
Targeting Mitochondrial Dynamics in VEGFR-TKI Hypertension and Cardiotoxicity [0.03%]
靶向血管生成抑制剂诱发的高血压和心肌毒性的线粒体动力学作用机制研究
Stanislovas S Jankauskas,Urna Kansakar,Pasquale Mone et al.
Stanislovas S Jankauskas et al.
Validated Automated Cuff Blood Pressure Devices for Children: STRIDE BP Report and Call to Action [0.03%]
儿童有效上臂血压自动测量装置：STRIDE-BP报告及行动呼吁
George S Stergiou,Ariadni Menti,Paolo Palatini et al.
George S Stergiou et al.
Background: Similar to adults, in children automated cuff devices are recommended for office, home, and ambulatory blood pressure (BP) measurement. However, a device validated in adults may not be accurate in children, an...