Heart Rate and Cardiovascular Outcomes in Post-Myocardial Infarction Patients Treated by β-Blockers: A Secondary Analysis of the ABYSS Trial [0.03%]
β受体阻滞剂治疗的心肌梗死后患者的心率与心血管预后:ABYSS试验的二次分析
Michel Zeitouni,Niki Procopi,Guillaume Cayla et al.
Michel Zeitouni et al.
Background: Heart rate (HR) is a key prognostic factor after myocardial infarction (MI), but its relevance in the modern reperfusion era is uncertain. We aim to evaluate the association between HR and β-blocker interrupt...
Endothelial SHMT2 Drives Pulmonary Vascular Remodeling Through Noncanonical Pathway in Pulmonary Hypertension [0.03%]
内皮细胞SHMT2通过非经典途径驱动肺高血压血管重塑
Qianqian Wang,Jingjing Tian,Dongdong Liu et al.
Qianqian Wang et al.
Background: Pulmonary hypertension (PH) is a progressive, life-threatening disease characterized primarily by pulmonary vascular remodeling in which endothelial dysfunction plays a vital role. However, the molecular facto...
Loss of STMP1 Perturbs Mitochondrial Cristae and Drives Cellular Inflammation and Heart Failure [0.03%]
STMP1丢失扰乱线粒体嵴并引发细胞炎症和心力衰竭
Francesco Paolo Ruberto,Chang Jie Mick Lee,Matthew Ackers-Johnson et al.
Francesco Paolo Ruberto et al.
Background: Heart failure is a leading cause of morbidity and mortality worldwide, particularly among the growing elderly population. In degenerative aging and autoimmune diseases, the cytoplasmic leak of mitochondrial DN...
David D Berg,Erin A Bohula
David D Berg
2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines [0.03%]
2026 AHA/ACC/ADA/ASN心血管-肾脏-代谢综合征预防、检测、评估和管理指南:美国心脏病学会/美国心脏协会联合临床实践指南委员会报告
Writing Committee Members;Chiadi E Ndumele,Fatima Rodriguez,Dave L Dixon et al.
Writing Committee Members;Chiadi E Ndumele et al.
Aim: The "2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome" retires, replaces, and expands upon the "2013 AHA/ACC/TOS Guideline for the M...
Use of Predicted Risk and Expected Benefit to Guide Decision-Making in Cardiovascular-Kidney-Metabolic Syndrome for the Primary Prevention of Cardiovascular Disease: A Scientific Statement From the American Heart Association and American College of Cardiology [0.03%]
使用预测风险和预期益处指导心血管-肾脏-代谢综合征在心血管疾病一级预防中的决策:美国心脏协会和美国心脏病学院科学声明
Sadiya S Khan,Nicole Bhave,Roger S Blumenthal et al.
Sadiya S Khan et al.
Current clinical practice guidelines for the primary prevention of cardiovascular disease recommend risk assessment to align the type and intensity of preventive efforts with an individual's risk. The 2025 American Heart Association/America...
Alternative Splicing of TPM1 Mediated by SRPK3 Drives Cardiac Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction [0.03%]
SRPK3介导的TPM1可变剪接驱动心力衰竭射血分数保留型心脏舒张功能障碍
Qian Chen,Xiaoping Wang,Ziyi Yin et al.
Qian Chen et al.
Background: Heart failure with preserved ejection fraction (HFpEF) has become the most prevalent type of heart failure, a condition characterized by impaired diastolic function and elevated left ventricular stiffness. TPM...
Response by Moura-Ferreira et al Regarding Article, "Prognostic Value of Exercise Right Ventricular-Pulmonary Arterial Coupling in Primary Mitral Regurgitation" [0.03%]
莫拉-费雷里对“运动时右心室-肺动脉耦合在原发性二尖瓣反流中的预后价值”一文的回应
Sara Moura-Ferreira,Nicola Riccardo Pugliese,Jan Verwerft
Sara Moura-Ferreira
Yun-Tao Zhao,Zhao-Wei Yin,Yen-Shu Huang et al.
Yun-Tao Zhao et al.