A Tandem Catalytic Approach for the Synthesis of Aminophenones Using an Amine-Integrated Bifunctional Cobalt-NHC Complex [0.03%]
一种用于合成氨基酮的串联催化方法及其胺结合双功能钴-NHC复合金属配合物催化剂
Biswaranjan Boity,Arpita Sahoo,Arnab Rit
Biswaranjan Boity
We report herein a bifunctional CoIII-NHC complex promoted unique protocol for generating diverse aminophenones from oxindole using aliphatic alcohols and aerial O2 under mild conditions. The unparalleled dual functionality of this cobalt-c...
Hypervalent Iodine(III) Carboxylates Enable Direct Radiosynthesis of 18F-Labeled Aliphatic Sulfonyl Fluorides [0.03%]
三价碘羧酸盐使脂肪族磺酰氟的直接氟-18放射合成成为可能
Yifan Shi,Chuanzhi Huang,Ziqiang Wang et al.
Yifan Shi et al.
Sulfur(VI) fluoride exchange (SuFEx) chemistry has enabled the widespread use of sulfur-fluoride compounds in diverse fields, particularly in positron emission tomography (PET) imaging. However, efficient methods for incorporating SO2-18F i...
An Orthogonally Functionalizable Tetrazine Building Block for Dual-Conjugated Bioorthogonal Probes [0.03%]
一种用于双重连接生物正交探针的正交功能化四嗪砌块
Bing-Feng Wang,Ke Chen,Xirui Liu et al.
Bing-Feng Wang et al.
The development of multifunctional bioorthogonal tools is essential for expanding their utility in biomedical research. Here, we report a gram-scale accessible building block, 3-(mesyloxyethyl)-6-(diethylphosphonomethyl)-tetrazine, featurin...
Peri-Annulations Bestow Configurational Stability onto Chiral Molecular Graphene Bowls [0.03%]
peri-annulations使手性分子石墨烯碗具有构象稳定性
Jovana Stanojkovic,Dániel Csókás,Raktim A Saikia et al.
Jovana Stanojkovic et al.
Corannulene-based bowl-shaped nanographenes are studied for their barrier to racemization (bowl inversion) through variable-temperature NMR spectroscopy and DFT-based theoretical calculations. The results indicate that in contrast to ortho-...
Haruki Sanematsu,Kazuo Takimiya
Haruki Sanematsu
Accumulation of π-conjugated structures is a promising strategy for developing new optoelectronic materials. We report the synthesis and characterization of peropyrene oligomers in different connecting manners. For the synthesis of the oli...
The epi-Matteson Reaction: Addition of Sodium Iodide in the Substitution Step Allows for a Stereodivergent Outcome [0.03%]
立体发散的Matteson反应：亚碘酸钠在取代步骤中的应用
Hae Mo Lee,Hans-Gert Korth,Noah Heger et al.
Hae Mo Lee et al.
The product of a Matteson homologation sequence is determined by the chiral director. Upon iterative application, this limits stereochemical variability. In this work, a method for the stereodivergent synthesis of alkyl-substituted Matteson...
Charles Enlow,Riley N Brown,Trevor E Hoodenpyle et al.
Charles Enlow et al.
This letter describes a catalytic, α-selective glycosylation of fucosyl chloride donors mediated by a nucleophilic thiourea. This reaction is highly selective in forming both α-fucosyl and α-2-deoxy-2-azido-fucosylated glycosides, includ...
JBIR-160-166 Obtained from the Heterologous Expression of a Cryptic Gene Cluster in Kitasatospora setae [0.03%]
隐秘基因簇的异源表达获得源自北里丛梗孢菌具有生物活性的新代谢物
Takehiro Nishimura,Kei Kudo,Miho Izumikawa et al.
Takehiro Nishimura et al.
The heterologous expression of unidentified gene clusters is a strategy for obtaining new natural products. Acyltransferases in polyketide synthases (PKSs) are responsible for loading extender units. Notably, the type I PKS biosynthetic gen...
Steric Effects of β-Annulated Pyrroles Trigger the Formation of Ethynylene-Bridged Hexaphyrinogen versus Ethynylene-Cumulene-Linked Aromatic [30] π Hexaphyrin [0.03%]
桥联乙炔基-桥连cumulene连接的芳烃[30]π六吡咯烷的形成触发了β取代的吡咯的立体效应
Sumit Sahoo,Daniel Blasco,Pallab Chatterjee et al.
Sumit Sahoo et al.
Peripherally constraining macrocycles using arene-annulated pyrrole rings, the first solid-state structural isolation of a stereoselective αααα conformer of core-modified hexaphyrinogen with phenanthrene-fused pyrrole rings versus visib...
The Ylide Dance: Base-Induced Furan Synthesis via Formal [3+2] Annulation of Phenacyl- and Alkenyl Sulfonium Salts [0.03%]
通过芳亚基和烯基锍盐的 formal [3+2] 加成构建含氮杂环化合物的新方法研究
Danil A Myasnikov,Anastasia Y Khodus,Elena Y Mendogralo et al.
Danil A Myasnikov et al.
A methodology for the synthesis of substituted furans via an "ylide dance" sequence has been developed. The reaction involves phenacyl sulfonium salts and alkenyl- or propargyl sulfonium salts under basic conditions. The key feature is a st...