Copper-Catalyzed Selective N-Sulfenylation of Tryptophan-Containing Peptides [0.03%]
铜催化色氨酸肽的N-磺ениylation反应
Jian Tang,Qinyu Lu,Han Chu et al.
Jian Tang et al.
Site-selective modification of peptides is essential for biomedical research; herein, we develop a versatile strategy for the late-stage functionalization of peptides through copper-catalyzed N-sulfenylation of tryptophan residues. This met...
Ligand-Promoted Palladium-Catalyzed [4 + 4] Cycloaddition Affording Benzo[ d]isothiazole 1,1-Dioxide-Fused Chiral Eight-Membered N-Heterocycles [0.03%]
配体促进的钯催化[4+4]环加成反应生成苯并[d]异噻唑-1,1-二氧化物稠合的手性八元氮杂环化合物
Weixin Xiao,Zhengyi Yi,Yong Liu et al.
Weixin Xiao et al.
Synthesis of chiral eight-membered rings with high regioselectivity and stereoselectivity has been a great challenge in asymmetric catalysis. There is no report on the synthesis of benzo[d]isothiazole 1,1-dioxide-fused chiral eight-membered...
Mutual Enrichment of the (Photo)Chemistry of Sydnones and Diarylethenes in Their Hybrids [0.03%]
.sydnones和 diarylethenes杂环化合物的（光）化学相互增益
Anna A Faizdrakhmanova,Vladimir B Kharitonov,Yulia V Nelyubina et al.
Anna A Faizdrakhmanova et al.
Hybrids of mesoionic sydnone and photoswitchable diarylethene (SyDAEs) exhibited properties uncommon for either class of molecules. Their (photo)chemical reactivity is determined by the size of the central ring, unifying the two functional ...
B(C6F5)3-Catalyzed Dearomative [2π+2σ] Cycloaddition of 1-Naphthols with Bicyclo[1.1.0]butanes [0.03%]
硼 triflate 催化的萘酚与双环[1.1.0]丁烷的去芳构化[2π+2σ]环加成反应
Lin Li,Lei Xiao,Zhongyu Yi et al.
Lin Li et al.
Converting planar arenes into C(sp3)-rich three-dimensional frameworks is an effective route to access bioisosteres of functional compounds. However, it remains challenging due to the inherent thermodynamic stability and kinetic inertness o...
Synthesis of Carborane-Functionalized Macrocycles: Bond-Angle-Modulated Cavities and Cation-Mediated Assembly [0.03%]
功能化碳硼烷大环的合成：夹角调节的空腔和阳离子介导的组装反应
Ying-Zheng Ren,Nian Si,Peng-Fei Liu et al.
Ying-Zheng Ren et al.
Herein, a novel synthetic strategy for macrocycles based on a three-dimensional carborane skeleton via a cyclization reaction was developed. Further substrate scope experiments confirm that this strategy possesses excellent reaction compati...
Li Li,Shiqing Huang,Yingjian Gong et al.
Li Li et al.
The stereocontrolled construction of polycyclic architectures from linear precursors remains a significant challenge, particularly for medium-sized rings, where strain and conformational flexibility hinder efficient cyclization. Herein, we ...
Copper-Catalyzed Domino Reaction of Arylidene Isoxazolones with 2-(Pyridin-2-yl)acetate Derivatives under Ball Milling: A Rapid and Economical Synthesis of 3-Acylindolizines [0.03%]
铜催化下偶氮异咯烷与2-(吡啶-2-基)乙酸衍生物球磨反应：3-酰基吲哚嗪的快速经济合成
Xing-Wang Hu,Luan-Ting Wu,Zeng-Yang He et al.
Xing-Wang Hu et al.
A copper-catalyzed domino reaction of arylidene isoxazolones with 2-(pyridin-2-yl)acetate derivatives under ball-milling conditions has been developed. This protocol provides a rapid and economic approach to constructing a vast variety of b...
Cethrene's Catch-22: Is Trading Magnetism for Bistability Inevitable? [0.03%]
凯塞琳的两难选择：磁性交换 bistability 是必然的吗？
Pauline Pfister,Daniel Čavlović,Tamara Trajkovic et al.
Pauline Pfister et al.
Cethrenes represent a promising platform for realizing all-organic magnetic photoswitches─provided that three requirements are met. The open form needs a thermally accessible triplet state to unlock magnetic properties, its energy relative...
A Cyclic tris-BODIPY Complex Derived from Dithienopyrrole Embedded [48]Dodecaphyrin (1.0.0.1.0.0.1.0.0) as Photoacoustic Contrast Agent [0.03%]
一种基于嵌入式双噻吩吡咯的[48]十二苯并二十一元环四吡咯（1.0.0.1.0.0.1.0.0）的三BODIPY衍生物光声成像造影剂研究
Gayathri Krishnan,Jayaprakash Ajay,Aathira Edwin et al.
Gayathri Krishnan et al.
A rigid dithienopyrrole embedded dodecaphyrin and its tris-BODIPY (bis(triisopropylsilyl-ethynyl)-substituted boron-dipyrromethene (BODIPY)) complex have been synthesized. DFT analysis showed a "ruffled" structure for dodecaphyrin and a sad...
Synthesis of (Hetero)aryl Fused 4 H-Quinolizin-4-ones from N-Ts Substituted (Hetero)arylamides and Pyridotriazoles [0.03%]
由N-Ts取代的芳基/杂芳酰胺与三氮唑并吡啶反应合成稠环4H-噌啉酮类化合物
Xin Yang,Bo Mei,Yiting Chang et al.
Xin Yang et al.
This paper describes a practical synthetic method of (hetero)aryl fused 4H-quinolizin-4-ones via (hetero)aryl sp2 C-H carbenoid functionalization of (hetero)aryl amides using pyridotriazoles with good functional group tolerance. This proces...