Nickel Nanoparticles Catalyzed Cross-Coupling of Diazo Compounds with O-Benzoyl Hydroxylamines [0.03%]
Linqian Tang,Haojun Hu,Ting Cheng et al.
Linqian Tang et al.
Nickel nanoparticle-catalyzed cross-coupling of diazo compounds with O-benzoyl hydroxylamines via a nickel carbene intermediate was disclosed in this work. A nickel nanoparticle catalyst was generated in situ to decompose diazo compounds to...
Chunxue Pu,Jianwei Wang,Yan Cao et al.
Chunxue Pu et al.
A palladium-catalyzed tandem cyclization and amination of bicyclobutyl (BCB) amides has been disclosed for the assembly of fused spiroquinolinone skeletons. By using di-t-butyldiaziridinone as the amination reagent, the reaction of bicyclob...
Visible-Light-Driven (E)-β-Trifluoromethylation of Enamides via In Situ Generated Sulfur(VI) Photosensitizers [0.03%]
Caiwen Wan,Changtong Shao,Ruolan Leng et al.
Caiwen Wan et al.
We report an autoinductive, visible-light-mediated (E)-β-trifluoromethylation of enamides using sodium trifluoromethanesulfinate. This protocol eliminates exogenous catalysts by leveraging an in situ generated pentacoordinate sulfur(VI) sp...
Metal-Free Photoredox-Catalyzed Anti-Markovnikov Phosphinothiolation of Styrenes: Chemodivergent Access to S-Alkyl-phosphinothioates and β-Keto-phosphinothioates [0.03%]
Souvik Roy,Saloni Kumari,Saira Banu et al.
Souvik Roy et al.
Anti-Markovnikov hydrophosphinothiolation of alkenes is quite challenging and is rarely explored. Herein, we report a visible-light-mediated metal-free multicomponent coupling strategy for the anti-Markovnikov hydrophosphinothiolation of st...
Et3SiOBpin as a Dual Reagent Enabled Photocatalytic Stereoselective Assembly of Multisubstituted Perfluoroalkyl-boryl Styrenes [0.03%]
Xiaobing Wang,Yuan Wu,Chenchen Zhao et al.
Xiaobing Wang et al.
Repurposing waste materials that would otherwise be discarded and finding new pathways for them to participate in reactions for recycling are parts of a highly atom-economical and environmentally friendly strategy. Drawing upon this concept...
Stereoselective Synthesis of Elaborate Fragments of Vancoresmycin and Amycomycin Enable Full Stereochemical Assignment [0.03%]
Max Schönenbroicher,Maximilian Seul,Simon Morgenschweis et al.
Max Schönenbroicher et al.
Efficient syntheses of three elaborate fragments of the complex polyketide antibiotics vancoresmycin and amycomycin were accomplished by concise strategies including various boron mediated couplings, an innovative Cu-catalyzed β-boration a...
Synthesis of Tetrakis(amino)ethylene-Derived Organic Reductants via Thermal Decomposition of Tris(amino)methanes [0.03%]
Seoyeon Kim,Xiaofan Jia,Nilay Hazari et al.
Seoyeon Kim et al.
Tetrakis(amino)ethylene (TAE)-based reductants are valuable in organic transformations, such as cross-electrophile coupling, but are not widely utilized due to their high cost and complicated syntheses. Here, we report the one-pot synthesis...
Sustainable Synthesis of N-Substituted Pyrroles via Fe-Catalyzed One-Pot Multicomponent Reaction [0.03%]
Santana Chakraborty,Arijit Singha Mohapatra,Nanda D Paul
Santana Chakraborty
Herein, we present a one-pot strategy for synthesizing N-substituted pyrroles from readily accessible feedstocks, such as alcohols, diols, and amines, catalyzed by a well-defined Fe(II)-catalyst featuring a redox-active azo-aromatic-1,10-ph...
Development of Nuclear-Targeted Photoaffinity Probes with Cleavable Disulfide Bonds for Enhancing Selectivity in hPTM Interactome Profiling [0.03%]
Bei-Chen Wang,Shuo Yang,Fang-Hui Chen et al.
Bei-Chen Wang et al.
Cell-penetrating, nuclear-targeted histone photoaffinity probes enable histone post-translational modification (hPTM) interactome profiling in native cells, yet noncleavable cell-penetrating peptides (e.g., cyclic polyarginine cell-penetrat...
Paired Electrolysis-Promoted Ni-Catalyzed Decarboxylative Cross-Couplings of Potassium Malonate Monoesters with Aryl Bromides [0.03%]
Shuai Lv,Qianyun Zhang,Jinzhong Yao et al.
Shuai Lv et al.
We report a paired electrolysis-promoted Ni-catalyzed decarboxylative cross-coupling of aryl bromides with potassium malonate monoesters. Carried out in an undivided electrolytic cell under mild reaction conditions, this strategy exhibits b...