Cobalt(III)-Catalyzed Selective β-C(sp2)-H Alkynylation of Acyclic Enamides with Bromoalkynes [0.03%]
钴(III)催化溴代炔烃与无环烯酰胺的选择性β-C(sp2)-H烷ynylation反应
Xiaolan Li,Jie Liu,Yiyan Lin et al.
Xiaolan Li et al.
A cobalt(III)-catalyzed selective β-C(sp2)-H alkynylation of acyclic enamides with easily accessible bromoalkynes has been successfully achieved. The reaction has a broad substrate scope as well as a good functional group tolerance. This p...
Synthesis of C2-Iodoindoles via an Aromatic Finkelstein-Type Halide Exchange under Mild Conditions [0.03%]
温和条件下通过芳香族芬克尔斯坦型卤化物交换合成C2-碘吲哚化合物
Yang Lv,Songren Xue,Xiang Zhang et al.
Yang Lv et al.
A mild, metal-free halide exchange protocol was developed for the synthesis of C2-iodoindoles from readily available C2-chloroindoles. The transformation is carried out under ambient conditions using potassium iodide and trifluoroacetic aci...
A High-Energy Low-Sensitivity Zwitterionic Material Featuring a Superhydrogen-Bonding Network Structure [0.03%]
一种超氢键网络结构的高能低灵敏度双离子型材料
Xiangyu Niu,Jie Tang,Caijin Lei et al.
Xiangyu Niu et al.
In the field of energetic materials research, enhancing energy density remains the paramount objective, whereas conventional approaches inevitably compromise stability. This study developed an innovative "nitro-hydroxy cooperative incorpora...
Stereoselective Synthesis of Fluoroalkenes via Electrocatalytic Defluorinative Coupling [0.03%]
电催化脱氟偶联制备含氟烯烃的立体选择性合成
Wangzhe Chen,Yuntian Shi,Zhen Wang et al.
Wangzhe Chen et al.
We report an electrochemically driven nickel-catalyzed protocol based on sequential ligand relay catalysis (SLRC), enabling divergent access to difluoroalkenes, monofluoroalkenes, and terminal alkenes. Mechanistic studies reveal that the di...
Nickel-Catalyzed Alkenylation of N-Heteroarenes with Fluorinated Alcohols: Direct Access to CF3-Embedded Olefins [0.03%]
镍催化N杂芳烃与氟化醇的加成反应直接构建嵌有CF3的烯烃类化合物
Shuvojit Haldar,Atanu Bera,Adrija Ghosh et al.
Shuvojit Haldar et al.
Herein, a sequential Ni-catalyzed acceptorless dehydrogenation followed by condensation of bench-stable fluorinated alcohols with 2-oxindoles or methyl N-heteroarenes to CF3-embedded olefins is reported. The protocol is tolerant to a series...
Conia-Ene Cyclization of Pyrazolones with o-Alkynyl Aldehydes: A Strategic Shift from Classical Condensation to Spiroannulation [0.03%]
吡唑酮与o-烯丙基甲醛的coni-ene环化反应：从经典缩合到螺环化的战略转变
Muskan,Akhilesh K Verma
Muskan
An unprecedented, atom-economic, and regioselective Conia-Ene cyclization from readily accessible pyrazolones and o-alkynyl aldehydes has been developed for the synthesis of spirocyclic frameworks. This protocol operates under mild reaction...
Direct Synthesis of (Radio)difluoromethylated Selenides via Organic Photoredox Catalysis [0.03%]
基于有机光氧化还原催化的(放射)氟甲硒烷的直接合成法
Yi Fang,Jingwen Li,Chunyi Liu et al.
Yi Fang et al.
Herein we describe a practical synthesis of difluoromethylated selenides enabled by organophotoredox catalysis. A diverse range of functionalized selenides were efficiently constructed from selenosulfonates and commercially available BTSO2C...
Jing Wang,Zenghui Li,Kaixing Gu et al.
Jing Wang et al.
Since the first report of trityl luminescence in 1944, ortho-substituent modification of pristine trityl has been synthetically challenged. So far, air-stable polyhalogenated trityls have shown remarkable luminescent properties. Herein, six...
Synthesis of Uracil Containing Oxazolidinone Derivatives by Using Uracil-BX and NaHCO3 as a Solid Surrogate of CO2 [0.03%]
尿嘧啶制备含氧氮杂环丁酮衍生物及其固态二氧化碳替代物的研究
Md Abbasuddin Sk,Sukanya Das,Mainak Pramanik et al.
Md Abbasuddin Sk et al.
We report a straightforward Pd(II)-catalyzed three-component strategy for the synthesis of uracil-oxazolidinone hybrids, wherein NaHCO3 acts as a solid CO2 surrogate and the newly developed hypervalent iodine reagent Uracil-BX enables effic...
One-Pot Construction of CF3-Tetrahydroindeno[1,2- b]pyrrol-4(1 H)-ones from 2-[3-(Trifluoromethyl)but-3-en-1-yn-1-yl]benzaldehyde Derivatives and Primary Aliphatic Amines [0.03%]
2-[3-(三氟甲基)丁-3-烯-1-炔-1-基]苯甲醛衍生物和伯脂肪胺一锅法合成CF3 -四氢茚并[1,2-b]吡咯-4(1H)-酮类化合物
Bin Wang,Zekun Li,Hua Cao
Bin Wang
This study successfully developed an efficient one-pot NHKM (nucleophilic addition, hydrolysis, Knoevenagel condensation, and Michael addition) reaction for synthesizing CF3-tetrahydroindeno[1,2-b]pyrrol-4(1H)-one from 2-[3-(trifluoromethyl...