Brønsted Base-Catalyzed Aminoxylation of Benzylic and Allylic Compounds with TEMPO [0.03%]
布朗斯特碱催化TEMPO氧化亚胺与苄位和烯丙位亲核试剂的反应
Azusa Kondoh,Masahiro Terada
Azusa Kondoh
A Brønsted base-catalyzed aminoxylation of benzylic and allylic compounds was developed. The reaction differs mechanistically from the existing aminoxylation of simple hydrocarbons and involves the catalytic generation of benzyl and allyl ...
Yellow-Light-Mediated Synthesis of Amidoximes via Radical gem-Diamination of Diazo Compounds [0.03%]
叠氮化合物经自由基gem-二胺化制备肟氨腈的黄光介导合成法
Yi-Lin Zhao,Xiao-Ling Jin,Qiang Liu
Yi-Lin Zhao
N-Nitrosamines serve as bifunctional reagents to install both amino and nitroso groups across unsaturated bonds, yet their use as diamine reagents remains underdeveloped. Herein, we introduce a simple yellow-light-driven reaction that direc...
Electrochemical Azidoarylthiation of Aryl Olefin and Enol Ethers [0.03%]
偶极亚硝基锂化合物促进的去对映选择性[5+2]环化反应构造含氮螺环骨架
Rongxin Yang,Fuqiao Xing,Hongjian Song et al.
Rongxin Yang et al.
We have developed a green electrochemical method for azidoarylthiation of styrenes and enol ethers by employing trimethylsilyl azide as a nucleophile and diaryl disulfides and aryl thiols as atom-economical arylthio sources under oxidant- a...
Copper-Catalyzed Intermolecular Aminotrifluoromethylation of Alkenes with Free Anilines [0.03%]
铜催化自由苯胺和烯烃的脱芳构化三氟甲基胺化反应
Zhang-Long Yu,Yan Tan,Jin-Xiong Chen et al.
Zhang-Long Yu et al.
A general copper-catalyzed intermolecular aminotrifluoromethylation of alkenes with free anilines and Togni's reagent is reported. Distinguished by its versatile reactivity, this protocol enables the coupling of diverse primary and secondar...
Chlorjaponoids A and B, Two Lindenane-Guaiane Sesquiterpenoid Dimers with a Cage-like Tetracyclo[8.5.0.02,7.03,13]pentadecane Scaffold from Chloranthus japonicus [0.03%]
含笼状并四环[8.5.0.0₂,₇.0₃,₁₃]十五烷骨架的日本山苏素A和B
Lu Gan,Xin-Yi Hu,Rong Huang et al.
Lu Gan et al.
Two heterodimeric sesquiterpenoids, chlorjaponoids A (1) and B (2), were isolated from the whole plants of Chloranthus japonicus. Their structures, characterized by a unique cage-like tetracyclo[8.5.0.02,7.03,13]pentadecane scaffold, were e...
Phenylthioethyl (Pte)/Phenylsulfonylethyl (Pse) as Safety Catch Protecting Groups for Peptide Synthesis [0.03%]
苯基硫代乙基(Pte)/ 苯磺酰乙基(Pse) 保护基作为肽合成的安全锁保护基团
Sunday Adewale Akintelu,Sikabwe Noki,Kwazi Masuku et al.
Sunday Adewale Akintelu et al.
A safety-catch protecting group allows for the use of the same reagent/chemical mechanism for the removal of different protecting groups in the same synthetic scheme. While the first of these is removed directly, the removal of the second r...
Regioselective Thiolation and Selenylation of Cyclic Diaryl λ3-Bromanes Enabled by Visible-Light Photocatalysis [0.03%]
可见光催化区域选择性硫化和硒化环状 diaryl λ3-溴烷基化合物
Xue-Ying Yang,Qiang Wang,Si-Rui Jia et al.
Xue-Ying Yang et al.
Despite the broad utility of cyclic diaryl λ3-bromanes as aryne precursors for nucleophilic additions by heteroatom-based nucleophiles under mild basic conditions, their capacity to install arylchalcogen bonds in a regioselective manner is...
Electrochemical Activation of α-Carbonyl Alkoxyamines for Direct Nucleophilic Substitution [0.03%]
α-羰基亚胺酯的电化学活化直接亲核取代反应研究
John Putziger,Elya Kandahari,Song Lin
John Putziger
The reactivity and synthetic utility of TEMPO-derived alkoxyamines as functional handles remains insufficiently explored. This report interrogates the factors governing the stereospecific substitution of electroactivated TEMPO-derived α-ca...
Hydrocarbon-Involved Sulfoxide Deoxygenation via Bifunctional Iron-Enabled Electron Buffering and Ligand-to-Metal Charge Transfer [0.03%]
双功能铁介导的含硫化合物脱氧茋反应中的溶剂化电子缓冲和配体至金属电荷转移机制研究
Lifang Wang,Bolin Qiao,Wenlong He et al.
Lifang Wang et al.
Sulfur-containing compounds are essential motifs of natural molecules. We herein report a photoinduced iron-catalyzed strategy for efficient sulfoxide deoxygenation under mild conditions. The iron catalyst as the sole additive acts dually: ...
Copper-Catalyzed Dearomative Cyclopropanation of Benzofurans with Diynes via Vinyl Cations [0.03%]
经乙烯基阳离子介导的二炔与苯并呋喃类化合物铜催化脱芳构化环丙烷化反应
Yi-Kao Xu,Yuan-Qing Dong,Jun Jiang et al.
Yi-Kao Xu et al.
Dearomative cyclopropanation of benzofurans is a powerful strategy for the assembly of valuable O-heterocycles. However, transition metal-catalyzed cyclopropanation of benzofurans is generally limited to diazo compounds. Herein, a copper-ca...