Yue Zhang,Jin-Hong Lin,Ji-Chang Xiao
Yue Zhang
The functionalization of cyclic ethers has received significant attention; however, the skeletal editing of cyclic ethers via O-to-N exchange remains challenging. Herein, we report a R3P/ICH2CH2I-promoted O-to-N exchange of cyclic ethers. T...
Samarium Diiodide-Mediated Radical Borylation of Alkyl Bromides with Pinacol Borane [0.03%]
溴代烷的夹心硼烷自由基硼化反应的研究：漏斗状过渡态钐介导的反应路径
Yilin Ma,Chengwei Liu
Yilin Ma
The first example of a samarium diiodide-mediated radical borylation reaction between alkyl bromides and pinacol borane was reported. Commercially available alkyl bromides and boron reagents were used as substrates in this method to constru...
Dearomative Indole Annulation with 2-Aminoaryldisulfide - an Approach for Accessing Polycyclic Indoline-Fused-Benzothiazine [0.03%]
2-氨基芳基二硫化物的去芳香化吲哚环化反应：并环式苯并噻唑啉酮类吲哚衍生物的新合成方法
Sudipta Baur,Sayari Chanda,Joydev K Laha et al.
Sudipta Baur et al.
Herein, we develop a practical protocol for the dearomative annulation of indoles with 2-aminoaryl disulfides under mild conditions for accessing three-dimensional (3D) indoline frameworks. The developed protocol shows remarkable tolerance ...
Modular Access to Boron Tripyrrolic Complexes from a Sequential Buchwald-Hartwig Amination/Boron Complexation Reaction [0.03%]
基于Buchwald-Hartwig芳胺化/硼复分解串联反应合成三吡咯并硼类模块化合物
Lei Zhang,Zhongxin Li,Guojun Li et al.
Lei Zhang et al.
We report a modular synthesis of novel boron tripyrrolic analogs, BOTPY, via a sequential Buchwald-Hartwig amination/boron complexation reaction from readily accessible α,α-dibromodipyrromethenes. This approach provides facile access to s...
Photoredox and CO2-Catalyzed Deep Skeletal Remodeling Via Merged C-H and C-C Bond Cleavages [0.03%]
基于C-H和C-C键断裂的融合策略实现分子深度重构及CO2催化官能团化反应
Kun-Long Song,Quentin Ordan,Maurice Médebielle et al.
Kun-Long Song et al.
Abundant C-H and C-C bonds can undergo homolytic cleavage through radical processes, enabling the subsequent formation of new C-C bonds that profoundly reshape molecular architectures. Yet, merging these distinct elementary steps into a sin...
Retraction of "One-Pot Synthesis Of Indolin-3-ones Mediated by LiN(SiMe3)2/CsF" [0.03%]
撤销文章“LiN(SiMe3)2/CsF催化的一锅法合成吲哚并吡啶”被撤销
Ruyuan Ma,Yuanyun Gu,Yan-En Wang et al.
Ruyuan Ma et al.
One-Pot Access to Dibenzodiazepines and 9-Arylacridines from a Cyclic Dienamine [0.03%]
cyclic diene胺制备二苯并二氮杂卓和9-芳基吖啶的新方法
Nikita Kanwar,Sachin Sharma,Prerna Priya et al.
Nikita Kanwar et al.
A synthesis of dibenzodiazepines and 9-arylacridines was achieved by reacting cyclic 1-amino-1,3-butadienes─derived from Morita-Baylis-Hillman adducts, with acetylene dicarboxylates. The transformations to both heterocycles proceeded throu...
Pyridine Synthesis via [3 + 2 + 1] Oxidative Cyclization of Enamines, Ethyl Tertiary Amines, and Alcohols: Copper-Catalyzed Cascade Multicomponent Poly C(sp3)-H Functionalization [0.03%]
通过亚胺、叔乙基胺和醇的[3+2+1]氧化环化合成吡啶：铜催化级联多组分分子内C(sp3)-H官能团化反应
Chengli Deng,Jingzhi Cheng,Zijing Bai et al.
Chengli Deng et al.
A copper-catalyzed [3 + 2 + 1] oxidative cyclization to access functionalized pyridines was descripted. Employing ethyl tertiary amine as a C2 source, alcohol as a C1 source, and easily handled enamines, one new C-N bond and two new C-C bon...
Visible-Light-Induced Radical [4 + 1] Annulation of Diazosulfonium Triflates with Cyclopropenes: Direct Synthesis of Benzofulvenes [0.03%]
可见光促进的茋
Xue-Cen Xu,Jie Wang,Yue Gong et al.
Xue-Cen Xu et al.
A visible-light-induced radical [4 + 1] annulation of diazosulfonium triflates and cyclopropenes has been established. In this process, diazomethyl radicals generated from diazosulfonium triflates undergo addition to cyclopropenes, followed...
Ruyuan Ma,Yuanyun Gu,Yan-En Wang et al.
Ruyuan Ma et al.
Isoindolinones are essential heterocycles with wide-ranging biological activities and medicinal values, and therefore, efficient approaches to their synthesis remain in demand. Herein, a novel and operationally simple method to generate iso...