Mitochondrially localized MPZL3 in the inner root sheath contributes to the regulation of human hair follicle cycling [0.03%]
线粒体定位的MPZL3调控人类毛囊周期
Takahiro Suzuki,Aysun Akhundlu,Jennifer Gherardini et al.
Takahiro Suzuki et al.
Shining a light on Jak inhibition: Partnering with NB-UVB to drive repigmentation in vitiligo [0.03%]
聚焦Jak抑制：与NB-UVB联手促进白癜风复色
Antonios G A Kolios,Julien Seneschal
Antonios G A Kolios
Mast cells fuel squamous cell carcinoma through a targetable MRGPRX2-IL-17A axis [0.03%]
肥大细胞通过可靶向的MRGPRX2-IL-17A轴促进鳞状细胞癌的发展
Chirag Vasavda,Ethan A Lerner
Chirag Vasavda
Monitoring senescent cell dynamics in wound healing using a p16-tdtomato mouse model [0.03%]
利用p16-tdtomato小鼠模型监测伤口愈合过程中衰老细胞的动态变化
Qiaoling Wang,Maria Shvedova,Magda Abdelkader et al.
Qiaoling Wang et al.
Although accumulating evidence implicates cellular senescence in acute wound healing, the precise roles of senescent cells within distinct cell lineages during this process remain elusive. To address this, we employed the p16-tdTomato repor...
Exploring global cfDNA fragmentomics as a biomarker in real-world melanoma patients [0.03%]
探索全球cfDNA片段组学作为真实世界黑色素瘤患者生物标志物的价值
Daniel Rizo-Potau,Anton Forniés-Mariné,José Luis Villanueva-Cañas et al.
Daniel Rizo-Potau et al.
Circulating cell-free DNA (cfDNA) fragmentomics-the analysis of cfDNA fragment-length profiles-has been explored as a biomarker across cancers, but evidence in melanoma is limited. We conducted a longitudinal prospective study of 235 AJCC s...
5-Fluorouracil use after the Veterans Affairs Keratinocyte Carcinoma Chemoprevention Study [0.03%]
退伍军人管理局角质细胞癌化学预防研究后的氟尿嘧啶使用状况
Marcelo L Paiva,Victoria M Hoffman,Christopher Halladay et al.
Marcelo L Paiva et al.
CCL3 and LPS Combination Therapy Significantly Reduces Infection and Stimulates Wound Healing in Diabetic Mice by Boosting Proinflammatory Responses [0.03%]
CCL3和LPS联合治疗通过增强促炎反应显著减少感染并促进糖尿病小鼠伤口愈合
Rajalekshmy G Padmakumari,Deepa Dehari,Getnet Tesfaw et al.
Rajalekshmy G Padmakumari et al.
In contrast to chronic diabetic ulcers that are trapped in persistent heightened inflammation, diabetic wounds early after injury suffer from inadequate inflammatory responses. We previously identified defective chemotactic response in diab...
Isabel Celac,Bao Trinh Nguyen,Danielle Larouche et al.
Isabel Celac et al.
Molecular differentiation of OX40 and OX40L targeted biologics using AlphaFold3 and molecular dynamics simulations [0.03%]
基于AlphaFold3和分子动力学模拟的OX40及OX40L靶向生物药分子差异化研究
Kelsey Nolden,Yuanjun Shi,Victor S Batista et al.
Kelsey Nolden et al.
Atopic dermatitis is a chronic inflammatory skin disorder that affects over 200 million people worldwide. Although disease etiology is multifaceted, the immune checkpoint molecules OX40 and OX40L have a critical role in disease development....
CLINICAL BENEFIT OF ADDING RADIATION FOR IMMUNE CHECKPOINT INHIBITOR-REFRACTORY MERKEL CELL CARCINOMA: A 27-PATIENT ANALYSIS [0.03%]
放疗联合免疫检查点抑制剂治疗 Merkel 细胞癌的临床疗效分析：27 例患者的单中心研究
Rian Alam,Ankita A Menon,Peter Y Ch&#x;en et al.
Rian Alam et al.
Merkel cell carcinoma (MCC) recurs in 40% of patients and 30% will require systemic therapy. While PD-(L)1 immune checkpoint inhibitors (ICIs) have improved outcomes for advanced MCC, over half of patients do not experience long-term diseas...