Mapping the global work-related impact of immune-mediated inflammatory skin diseases: a systematic review [0.03%]
基于免疫介导的炎症性皮肤病工作相关影响的系统评价
Fanny C Kpenou,Ju Hee Han,Marc Fadel et al.
Fanny C Kpenou et al.
Immune-mediated inflammatory diseases (IMIDs) of the skin can significantly affect individuals' work functioning and pose societal challenges. This systematic review examined the burden of common skin IMIDs (alopecia areata, atopic dermatit...
Divergent roles of TRPV1 and neuropeptides in mouse model of atopic dermatitis [0.03%]
瞬时受体电位香草素1通道和神经肽在小鼠过敏性皮炎模型中发挥不同作用
Joshua James Wheeler,Santosh Kumar Mishra
Joshua James Wheeler
Lipase GehA functions as a positive-feedback amplifier of Cutibacterium acnes-sebum interactions in acne pathogenesis [0.03%]
丙酸痤疮丙烷杆菌脂肪酶GehA在痤疮发病机制中作为皮脂-病原菌相互作用的正反馈放大器的功能
Yangfan Lai,Mengjie Fan,Xiaoyao Fan et al.
Yangfan Lai et al.
Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit in which Cutibacterium acnes interacts dynamically with the sebum microenvironment. The bacterial factors that sense and remodel this environment remain poorly chara...
Disease context dictates the cellular targets of IL-17 in inflammatory skin disease [0.03%]
疾病背景决定了IL-17在炎症性皮肤病中的细胞靶点
Kellen J Cavagnero,Fengwu Li,Haley Jo et al.
Kellen J Cavagnero et al.
IL-17 and TNF blockade effectively treats hidradenitis suppurativa and psoriasis, yet the relative importance of the different cell types that respond to IL-17 and TNF remains unresolved. Keratinocytes are viewed as the dominant effector ce...
Sally Connolly,Karoline Strobl,Carmen Tam-Amersdorfer et al.
Sally Connolly et al.
Langerhans cells (LCs) are long-lived, tissue-resident mononuclear phagocytes that form dense networks in stratified epithelia and migrate to draining lymph nodes to maintain immune tolerance. LC development and their immature epithelial id...
Grace T Yu,Robert S Kirsner,James L Kirkland et al.
Grace T Yu et al.
Depth-aware melanoma classification and Breslow depth estimation from reflectance confocal microscopy [0.03%]
基于反射共聚焦显微镜的深度感知黑色素瘤分类和Breslow深度估计
Ross O&#x;Hagan,Jaanvi Mehta,Alessandra Acciardi et al.
Ross O&#x;Hagan et al.
PHYTOCERAMIDES AND 6-HYDROXYCERAMIDES DEFICIENCY CORRELATES WITH BARRIER FUNCTION ALTERATION IN ATOPIC DERMATITIS SKIN [0.03%]
神经酰胺缺乏与特应性皮炎皮肤屏障功能障碍有关
Sonia Bouayadi,Eric Arbey,Edouard Raynaud et al.
Sonia Bouayadi et al.
Stratum corneum metabolomics suggests a subclinical biochemical state in non-lesional skin in atopic dermatitis [0.03%]
皮炎非损皮肤角质层代谢组学表明其处于亚临床生化状态
Mira Choi,Hyemi Jang,Seung Min Lee et al.
Mira Choi et al.
Self-antigen keratin 17 presented by keratinocytes promotes T cell auto-reactivity in psoriasis [0.03%]
角质细胞呈递自身抗原keratin 17促进银屑病T细胞自免疫反应
Chunying Xiao,Junfeng Hao,Yimeng Guo et al.
Chunying Xiao et al.
Psoriasis is a T cell-mediated inflammatory and autoimmune skin disease characterized by aberrant adaptive immune responses against specific autoantigens. Among the autoantigens implicated, keratin 17 (K17), an intermediate filament protein...