Deciphering MAPK dependence in epidermolysis bullosa-associated squamous cell carcinoma: Toward biomarker-guided MEK inhibition [0.03%]
解析表皮松解性角化病相关鳞状细胞癌中的MAPK依赖性:面向生物标志物引导的MEK抑制疗法
Jiuyuan Qin,Jie Deng,Yulin Zou
Jiuyuan Qin
Genes associated with immune response are upregulated in clinically healthy skin of patients with gliptin-associated bullous pemphigoid [0.03%]
与免疫反应相关的基因在甘磷酸关联性大疱性类天疱疮患者临床上健康皮肤中高表达
Nina Kokkonen,Outi Varpuluoma,Jussi Tuusa et al.
Nina Kokkonen et al.
A peripheral neurons-basophil axis drives heat-killed Staphylococcus aureus-induced dermatitis via TLR2 signaling pathway [0.03%]
TLR2信号通路介导的金黄色葡萄球菌热灭活菌诱导的皮肤炎中外周神经- basophil轴的作用
Hiroyuki Irie,Chisa Nakashima,Yoshihiro Ishida et al.
Hiroyuki Irie et al.
Spatial insights into psoriasis: A single cell transcriptomics pipeline to study inflammatory skin disease [0.03%]
银屑病的空间表型:一种用于研究炎症性皮肤病的单细胞转录组学流程
Chen Li,Kerry A Mullan,Jingran Ye et al.
Chen Li et al.
artificial intelligence-enabled precision medicine for inflammatory skin diseases [0.03%]
人工智能驱动的炎症性皮肤病精准医疗
Alice S Tang,Maria L Wei,Anna Haemel et al.
Alice S Tang et al.
Recent advances in artificial intelligence (AI) and multimodal data collection are revolutionizing dermatology. Generative AI and machine-learning approaches offer opportunities to enhance the diagnosis and treatment of autoimmune and infla...
Regulation of keratinocyte proliferation and epidermal inflammation by meprin α-mediated cleavage of dermokine [0.03%]
由皮肤蛋白酶α介导的表皮蛋白酶α介导的表皮增殖和炎症的调节
Vasco Köhling,Florian Peters,Inez Götting et al.
Vasco Köhling et al.
Dysregulations within the epidermal proteolytic network can cause hyperproliferative and inflammatory disorders. While the metalloprotease meprin α is localized in the stratum basale in healthy skin, increased levels are found in the upper...
Ino Song,Matthew Aaron Blumberg,Chen Yuan Kam
Ino Song
The cutaneous vascular network, located in the skin dermis, plays vital roles in thermoregulation, immune surveillance, and tissue regeneration. Despite its important functions, the cutaneous vasculature remains an understudied component of...
From single cells to organotypic cultures: Measuring and analyzing keratinocyte migration [0.03%]
从单个细胞到类器官培养:角质形成细胞迁移的测定与分析
Mayuri Vaish,Benjamin A Nanes
Mayuri Vaish
Keratinocyte migration is an integral part of epidermal development and homeostasis. Because of its complexity, no single experimental approach is sufficient to capture all aspects of cell migration. This review covers a range of strategies...
Identification of MITF-regulated transcript isoforms of ubiquitously expressed genes [0.03%]
MITF调节的泛表达基因转录异构体的鉴定
Stephen M Ostrowski,Eleanor Klibaner-Schiff,John Ming Zhang et al.
Stephen M Ostrowski et al.