Microdialysis-based metabolomic and proteomic profiling reveals signature variations for disease severity in psoriasis [0.03%]
微透析基元组和蛋白质组谱分析揭示了银屑病严重程度的特征变化规律
Lina Gross,Joerg Buddenkotte,Febu Joy et al.
Lina Gross et al.
Psoriasis is a common chronic inflammatory skin disease characterized by epidermal hyperproliferation and immune dysregulation. However, local metabolic interactions remain incompletely understood, and biomarkers for disease activity and tr...
Trials and tribulations of systemic inflammation and cardiovascular risk in psoriasis [0.03%]
银屑病患者全身性炎症与心血管风险的临床研究困境和挑战
Ravi Ramessur,Joel M Gelfand
Ravi Ramessur
Pathogenesis of cutaneous T-cell lymphoma: Malignant inflammation, immune reprogramming, and microenvironmental drivers [0.03%]
皮肤T细胞淋巴瘤的发病机制：恶性炎症、免疫重构和微环境驱动因素
Joana Calvão,Christoph Iselin,Johannes Wasmayr et al.
Joana Calvão et al.
Cutaneous T-cell lymphomas, namely mycosis fungoides and Sézary syndrome, arise through a complex interplay of genetic alterations, epigenetic deregulation, immune imbalance, and tumor-microenvironment interactions. A progressive T helper ...
Artificial intelligence in dermatology: Clinical promise and environmental impact [0.03%]
皮肤病学中的人工智能：临床应用前景与环境影响
Catherine Z Shen,Aaron T Zhao,Veronica Rotemberg et al.
Catherine Z Shen et al.
Artificial intelligence (AI) is reshaping dermatology through diagnostic image analysis, clinical documentation, and patient communication tools. However, AI's environmental costs remain largely invisible to clinicians. Because training lar...
Identifying the drivers of genetic risk in patients with multiple primary melanoma [0.03%]
识别多原发黑色素瘤患者遗传风险的影响因素
Andrew D King,David E Fisher
Andrew D King
Serum proteomic and single-cell transcriptomic profiling reveals immunoproteomic features distinguishing early-stage mycosis fungoides from atopic dermatitis [0.03%]
血清蛋白质组和单细胞转录谱分析揭示了早期蕈样肉芽肿与特应性皮炎在免疫蛋白组学的差异特征
Yoni Sacknovitz,Rachel Ma,Maggie H Zhou et al.
Yoni Sacknovitz et al.
Hideyuki Kosumi,Connie Rim,Mayumi Ito
Hideyuki Kosumi
Permissive skin microbiomes in WHIM syndrome: HPV and pathogen expansion [0.03%]
WHIM综合征中的皮肤菌群失调：HPV和致病菌的扩增
Peng Hou,You Che,Jungmin Han et al.
Peng Hou et al.
Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a rare inborn error of immunity (IEI) caused by hyperfunctional pathogenic variants in CXC chemokine receptor 4 (CXCR4), predisposing individuals to recurrent ba...
Psychological stress delays inflammatory resolution and promotes sustained sensory sensitization during recovery from atopic dermatitis [0.03%]
心理压力延缓了特应性皮炎恢复期的炎症反应分辨率并促进感觉过敏的持续存在
Qiaofeng Zhao,Alberto Leguina-Ruzzi,Mitsutoshi Tominaga et al.
Qiaofeng Zhao et al.
The role of neutrophils and neutrophil extracellular traps in Staphylococcus aureus colonization in healthy and inflamed skin [0.03%]
表皮葡萄球菌和炎性皮肤中的中性粒细胞及中性粒细胞胞外陷阱的作用关系研究
Jule Riebelmann,Birgit Schittek
Jule Riebelmann
Staphylococcus aureus (S aureus) commonly causes skin infections and is abundant on the skin of patients with atopic dermatitis, where it worsens inflammation and drives skin barrier defects. Neutrophils help to control S aureus infection t...