Genome-wide Study Identifies a Locus Associated with Atopic Dermatitis Severity in a Canine Model [0.03%]
全基因组研究在犬类模型中鉴定出与特应性皮炎严重程度相关的位点
Andrew Trujillo,Nathalie Munguia,Nicky Craig et al.
Andrew Trujillo et al.
Dendritic Cells Remodel Eccrine Sweat Gland Niche Metabolism Via Oxidative Phosphorylation During Aging [0.03%]
树突细胞通过氧化磷酸化在衰老过程中重塑汗腺生态位代谢
Yuanli Ye,Xiao Xiang,Xiaohan Liu et al.
Yuanli Ye et al.
Tissue function and homeostasis are sustained through dynamic interactions between resident cells and their surrounding microenvironment. In the skin, these niche-specific signals coordinate epithelial metabolism and secretory activity. Alt...
Mayra Betancourt Ponce,Alexa R Heaton,Samantha K Burkard et al.
Mayra Betancourt Ponce et al.
High-dose NB-UVB exacerbates vitiligo progression by inducing dermal fibroblast senescence via the p38 MAPK signaling pathway [0.03%]
高强度NB-UVB通过p38 MAPK信号通路诱导真皮成纤维细胞衰老从而加重白癜风进展
Hao Xu,Rong Jin,Aie Xu
Hao Xu
Vitiligo is an acquired and polygenetic autoimmune disorder with limited effective treatments. Dermal fibroblasts play a key role in vitiligo by responding to interferon-γ (IFN-γ) and secreting chemokines to recruit and activate CD8+ T ce...
Seeing beyond the visible: Visual literacy in 2 prints by Utagawa Kuniyoshi [0.03%]
见所未“见”——歌川国芳的版画艺术中的视觉素养
Corinne Déchelette,Philippe Charlier
Corinne Déchelette
Spatial Lipidomics-based Melanoma Diagnostics by Integration of Mass Spectrometry Imaging and Machine Learning [0.03%]
基于空间脂质组学的黑色素瘤诊断：质谱成像与机器学习的融合分析
Yu-Hsuan Chen,Jau-Yu Liau,Jia-Fang Tsai et al.
Yu-Hsuan Chen et al.
Melanoma is an aggressive skin cancer with a rising global incidence, yet its lipidomic alterations remain understudied. We applied desorption electrospray ionization mass spectrometry imaging (DESI-MSI) to 137 frozen skin specimens (65 pai...
Maurice A M van Steensel
Maurice A M van Steensel
The Regional Dermatology Training Center: Dermatologic care, education, and research in sub-Saharan Africa [0.03%]
东非区域皮肤病学培训中心：非洲撒哈拉以南地区皮肤护理、教育和研究
Gloria E Masenga,Annika B Wilder-Smith,Elisante J Masenga et al.
Gloria E Masenga et al.
Blockade for CD276-mediated suppression of tumor-specific CTLs may contribute to achieving durable responses with immune checkpoint inhibitors [0.03%]
针对特异性CTL的CD276介导的免疫检查点抑制剂耐药屏障可能是实现持久反应的障碍
Kazuhiro Aoyama,Shusuke Kawashima,Yuka Saeki et al.
Kazuhiro Aoyama et al.
The most significant advantage of ICIs for melanoma patients is their durable benefits. Particularly, most patients who achieve a complete response maintain long term relapse-free survival, even after the cessation of treatment. However, at...