Kit signaling is involved in hair follicle morphogenesis and regeneration in mice [0.03%]
Kir信号参与小鼠毛囊的发生和再生
Hitomi Aoki,Hiroyuki Tomita,Akira Hara et al.
Hitomi Aoki et al.
Keratinocytes are the predominant cell type in the epidermis. The mammalian epidermis is maintained by a pool of self-renewing stem cells that reside primarily in the basal layer of the interfollicular epidermis and within specialized niche...
Polycomb protein EED supports ultraviolet-induced effector regulatory T cell responses in cutaneous inflammation [0.03%]
组蛋白修饰酶EED支持紫外线诱导的皮肤炎症中的效应调节性T细胞活化
Eiki Sugimoto,Yoshihito Mima,Toyoki Yamamoto et al.
Eiki Sugimoto et al.
Population Pharmacokinetic-Pharmacodynamic Model for Secukinumab in Psoriasis Patients [0.03%]
银屑病患者司库奇尤单抗的群体药代动力学/药效动力学模型研究
Anke Eylenbosch,Rani Soenen,Charlotte A M van Riel et al.
Anke Eylenbosch et al.
Psoriasis is a chronic immune-mediated inflammatory disease for which biologic therapies have substantially improved clinical outcomes, yet long-term treatment costs and potential safety concerns highlight the need for dose optimisation. Mo...
Alain Hovnanian,Guillaume Mondon,Matthias Titeux
Alain Hovnanian
RNA therapeutics are a versatile class of medicines that exploit different types of RNA molecules to prevent or treat a wide spectrum of diseases. Compared with traditional small-molecule drugs, protein drugs, or gene therapies, these thera...
Wei-Hung Wang,Yu-Sheng Yu,Sung-Jan Lin
Wei-Hung Wang
Clinical and molecular improvements in pediatric patients with atopic dermatitis treated with dupilumab: an analysis from the TREATKids registry [0.03%]
Dupilumab治疗特应性皮炎患儿的临床和分子学改善：来着TREATKids注册研究的数据分析
Melina Fonfara,Dora Stölzl,Jan Hartmann et al.
Melina Fonfara et al.
Real-world evidence on clinical and molecular outcomes of systemic therapy for pediatric atopic dermatitis remains limited. Within the prospective TREATkids registry, we conducted an observational analysis of children and adolescents treate...
Harald M Oey,Yung-Ching Kao,Katie J Lee et al.
Harald M Oey et al.
Seborrheic keratosis is a common benign skin tumor that affects most individuals, particularly later in life. Despite its high prevalence, the underlying biology of seborrheic keratosis remains poorly understood. In this study, we performed...
Introducing lesion-level metrics for melanocytic neoplasm clustering: Practical tools with potential applications in clinical practice [0.03%]
介绍用于黑色素细胞肿瘤聚类的病灶水平指标：具有潜在临床应用价值的实际工具
Emmanouil Chousakos,Alexandros Stratigos
Emmanouil Chousakos
Reducing plastic waste in skin-model research: Sustainable packaging as a practical first step [0.03%]
皮肤模型研究中减少塑料废物：可持续包装作为实际第一步措施
Dusko Ilic,Sandrine Dubrac,Reiko J Tanaka et al.
Dusko Ilic et al.
Modern serum proteomics in precision medicine: Toward disease stratification and predictive, proactive treatment strategies [0.03%]
精准医学中的现代血清蛋白质组学：朝向疾病分层和预测性、主动性治疗策略
Yi-Chien Tsai,Emmanuella Guenova
Yi-Chien Tsai