Enhanced Staining and Imaging of Electrophoretically Separated Membrane Proteins Solubilized by SMA/DIBMA Polymers [0.03%]
由SMA/DIMBA聚合物变性并进行电泳分离的膜蛋白的增强染色及成像技术
Nilabh Saksena,Mahipal S Rao,Spencer C Moore et al.
Nilabh Saksena et al.
Recent advances in membrane protein biochemistry have enabled the isolation of complexes in detergent-free, near-native states using synthetic amphipathic copolymers such as styrene-maleic acid (SMA) and diisobutylene maleic acid (DIBMA). H...
Chiral Separation of Biosourced Preservatives: Greenness Evaluation of Liquid and Supercritical Fluid Chromatography Through AMGS and AGREE Tools [0.03%]
利用AMGS和AGREE工具评估液体和超临界流体色谱对生物基防腐剂拆分的绿色度
Bangaly Sylla-Toure,Clara Audignon,Théo Guerin et al.
Bangaly Sylla-Toure et al.
This study investigated the synthesis and chiral separation of a series of bio-based amide derivatives. Moreover, the greenness of both separation techniques, that is, high-performance liquid chromatography (HPLC) and supercritical fluid ch...
Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing [0.03%]
药物亚硝胺检测中的分析化学可持续性研究
Felix Bredendiek,Sebastian Schmidtsdorff,Maria Kristina Parr
Felix Bredendiek
Following the valsartan scandal in 2018, the testing of drug substances and drug products for N-nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three an...
A Similarity Principle-Based Multiscale Electrodialysis Desalination Unification With Multi-Physical Parameter Sensitivity Analysis [0.03%]
基于相似性原理的多尺度电渗析淡化统一模型及多物理参数敏感性分析
Baiqing Ye,Yu Qian,Yongbo Dong et al.
Baiqing Ye et al.
Electrodialysis (ED) is a promising seawater desalination technology using electricity. However, the existing research studies on ED mainly focus on design of electrode materials and device structure. The ED is a multiscale and multi-physic...
Mirror-Image β-l-Cyclodextrin as a Chiral Pseudophase in Capillary Electrophoresis [0.03%]
手性伪相(capillary electrophoresis中的镜像β-l-环糊精)
Saba Aslani,Ryan Jacob Burk,Yong Wu et al.
Saba Aslani et al.
Cyclodextrins (CDs) and their derivatives are among the most versatile and effective pseudophases used for chiral capillary electrophoresis (CE). They provide a variety of interactions that could be further expanded by derivatization. Among...
Assessment of Intra- and Intercapillary Variability in HbA1c Measurement Using the Sebia Capillarys OCTA3 Analyzer [0.03%]
塞比雅卡普勒斯OCTA3分析仪检测糖化血红蛋白(HbA1c)的组内和组间变异性的评估
Meriem Belhedi,Wiem Lazzem,Othman Bacha et al.
Meriem Belhedi et al.
Hemoglobin A1c (HbA1c) measurement is crucial for diabetes monitoring. Validation of analytical methods ensures the reliability of results. We verified the analytical performance of HbA1c measurement in each capillary of the Capillarys OCTA...
Muneeb Ur Rahman,Habiba Akram,Mubashra Saeed et al.
Muneeb Ur Rahman et al.
Green analytical chemistry (GAC) aims to achieve faster, safer, accurate, and sustainable analysis by minimizing the hazardous impact of organic solvents on the environment. Here, the focus will be on impurity profiling of pharmaceuticals. ...
Tuning Apparent Peak Efficiency in Capillary Electrophoresis Using Backscatter Interferometry Detection [0.03%]
利用背向散射干涉检测调节毛细管电泳表观峰值效率
Miyuru De Silva,Stanslaus M Kariuki,Robert C Dunn
Miyuru De Silva
Backscatter interferometry (BSI) is a refractive index detection method for capillary electrophoresis that is inexpensive, flexible, and easily miniaturized. Interestingly, unlike most detectors that respond exclusively to analyte concentra...
Carlos Vargas,Federico Méndez,Carlos Escobedo
Carlos Vargas
This work investigates electrokinetically driven protein transport in open microfluidic devices with microwells featuring axial shape variations. The results indicate that protein propagation, which is lysed at the surface, depends on two k...
Characterization of the Additional Pseudo-Crossover Frequency of Nanoparticles in Low Frequency Dielectrophoresis Regime [0.03%]
低频介电泳 regime 下纳米粒子额外伪交又频率的特征分析
Tae Joon Kwak,Khaled S Qananba,Mohammad Rizwen Ur Rahman et al.
Tae Joon Kwak et al.
Dielectrophoresis (DEP) is a powerful tool for manipulating particles using non-uniform electric fields. This study combines numerical simulations and experiments to investigate crossover frequencies (COFs) for micro- and nanoparticles in a...