San Wang,Rita H Tsay,Danya Zhang et al.
San Wang et al.
Older people are prone to involuntary fasting, but systematic assessment of their mobilization and oxidation of the three macronutrients during fasting has not been previously reported. Because of changes in body composition and metabolic r...
Umbilical Cord Plasma Markers in Gestational Diabetes: Evidence of Fetal Metaflammation, Elevated GGT, and Links to Neonatal Metabolic Health [0.03%]
胎盘糖尿病中的脐带血浆标志物：证据表明胎儿元炎症、GGT升高与新生儿代谢健康之间的联系
Andreas Steiner,Anna Rieder,Jasmin Zaunschirm-Strutz et al.
Andreas Steiner et al.
Gestational diabetes mellitus (GDM) is a form of glucose intolerance that develops during pregnancy, affecting approximately 14% of pregnancies worldwide. GDM leads to an excess supply of nutrients to the fetus, influencing fetal metabolism...
Changes in body composition and resting energy expenditure during the first year after Roux-en-Y or one-anastomosis gastric bypass [0.03%]
Roux-en-Y或一环形吻合胃旁路术后第一年内身体组成和基础能量消耗的变化
Jari E Karppinen,Sini Heinonen,Tuure Saarinen et al.
Jari E Karppinen et al.
Resting energy expenditure (REE) declines during weight loss because of both organ-tissue mass loss and adaptive thermogenesis, but their relative contributions after bariatric surgery remain unclear. Our primary aim was to quantify these c...
Postbiotic gut bacteria site-specific immunomodulators improve liver steatosis, inflammation, and fibrosis in obese mice with MASLD [0.03%]
一种后生元调节肠道菌群的特异性免疫改善肥胖小鼠MASLD肝脏脂变、炎症和纤维化
Rodrigo Rodrigues E-Lacerda,Nicole G Barra,Meghan O Conn et al.
Rodrigo Rodrigues E-Lacerda et al.
Obesity promotes metabolic dysfunction-associated steatotic liver disease (MASLD). Gut microbiota can influence MASLD through local communication between the gut and liver. Bacterial components are often conceptualized only as contributors ...
The Important Role of Fatty Infiltration of Skeletal Muscle in Aging: Skeletal Muscle Function, Pathological Mechanisms and Intervention [0.03%]
肌肉脂肪浸润在衰老中的重要作用：骨骼肌功能、病理机制和干预措施研究
Mei Yang,Fangli Zhou,Cui Wang et al.
Mei Yang et al.
This review explores the various biological changes that occur during the aging process, elucidating the fundamental pathological mechanisms leading to a decline in muscle integrity and functionality. A primary focus of the review is the oc...
Impact of AKR1C2 and AKR1C3 single nucleotide polymorphism rs28571848 in adipose tissues of individuals with severe obesity [0.03%]
AKR1C2和AKR1C3基因单核苷酸多态性rs28571848在重度肥胖者脂肪组织中的影响研究
Giada Ostinelli,Alan Ramalho,Marie-Fréderiqu Gauthier et al.
Giada Ostinelli et al.
Background: Adipose tissue androgen turnover, dictated at least in part by the enzymes AKR1C2 and AKR1C3, has been linked to abdominal obesity. Recently, we investigated a single-nucleotide polymorphism (SNP) named rs28571858, that might in...
12 weeks of voluntary wheel running restores glucagon sensitivity in middle-aged mice [0.03%]
12周自由跑轮恢复中年小鼠的胰高血糖素敏感性
Tyler J Marx,Kassandra R Bruner,Susma Ghimire et al.
Tyler J Marx et al.
Aerobic exercise training is a potent intervention for the treatment and prevention of age-related metabolic disease, which is characterized by both insulin and glucagon resistance. While insulin resistance is a key driver of metabolic dise...
Predicting Resting Metabolic Rate in healthy adults: A Comparative Analysis Using the enable cohort [0.03%]
利用enable队列预测健康成人静息代谢率的比较分析
Beate Brandl,Gloria-Maria Keppner,Quirin Manz et al.
Beate Brandl et al.
Background: Resting metabolic rate (RMR) is modulated by a variety of factors. Accurate prediction of RMR is essential for planning energy requirements but remains challenging due to inter-individual variability. Objective: This study aimed...
Hyaluronan 35 prevents endotoxin-mediated dysregulated skeletal muscle proteostasis during ethanol exposure [0.03%]
透明质酸35防止乙醇暴露期间内毒素介导的骨骼肌蛋白稳态失调
Nicole Welch,Pugazhendhi Kannan,Gangarao Davuluri et al.
Nicole Welch et al.
Introduction: Sarcopenia in alcohol-related liver disease (ALD) is of high clinical significance but there are no effective treatments. Hyaluronan 35kDa (HA35), a glycosaminoglycan polymer, modulates responses to TLR4, a ...