Eosinophil-associated microinflammation in the gastroduodenal tract contributes to gastric hypersensitivity in a rat model of early-life adversity [0.03%]
早期逆境大鼠模型胃肠道嗜酸性粒细胞微炎症与胃高敏感性的关联研究
Shaoqi Duan,Takashi Kondo,Hiroto Miwa et al.
Shaoqi Duan et al.
Gastric hypersensitivity is a major pathophysiological feature of functional dyspepsia (FD). Recent clinical studies have shown that a large number of patients with FD present with gastroduodenal microinflammation, which may be involved in ...
1907-2020: more than one century of colonic mass movements in humans [0.03%]
从1907年到2020年:人类结肠运动研究的百余年历程
Gabrio Bassotti
Gabrio Bassotti
Motility of the large bowel may be grossly subdivided in two types of contractile activity: low-amplitude single or cyclic propagated waves and high-amplitude propagated activity. The latter is mainly apt to shift relatively large amounts o...
Long-term trans-inhibition of the hepatitis B and D virus receptor NTCP by taurolithocholic acid [0.03%]
牛磺脱氧胆酸长期抑制乙肝和丁肝病毒受体NTCP
Kira A A T Lowjaga,Michael Kirstgen,Simon F Müller et al.
Kira A A T Lowjaga et al.
Human hepatic bile acid transporter Na+/taurocholate cotransporting polypeptide (NTCP) represents the liver-specific entry receptor for the hepatitis B and D viruses (HBV/HDV). Chronic hepatitis B and D affect several million people worldwi...
John D ONeill,Meghan R Pinezich,Brandon A Guenthart et al.
John D ONeill et al.
Gastrointestinal disease burden continues to rise in the United States and worldwide. The development of bioengineering strategies to model gut injury or disease and to reestablish functional gut tissue could expand therapeutic options and ...
Water intake accelerates ATP release from myofibroblast cells in rats: ATP-mediated podoplanin-dependent control for physiological function and immunity [0.03%]
水分摄入加速大鼠肌成纤维细胞中ATP的释放:ATP介导的肺泡修复和podoplanin依赖性免疫调控
Moyuru Hayashi,Tomomi Watanabe-Asaka,Sachiho Nagashio et al.
Moyuru Hayashi et al.
We previously demonstrated that water intake increased mesenteric lymph flow and the total flux of IL-22 in rat jejunum. The drained water and the higher permeability of albumin in the jejunal microcirculation contributed to increase the ly...
Blockage of protease-activated receptor 2 exacerbates inflammation in high-fat environment partly through autophagy inhibition [0.03%]
蛋白酶激活受体2拮抗在高脂环境部分通过自噬抑制加剧炎症反应
Ji Yun Her,Yunna Lee,Su Jin Kim et al.
Ji Yun Her et al.
Protease-activated receptor 2 (PAR2) regulates inflammatory responses and lipid metabolism. However, its precise role in colitis remains unclear. In this study, we aimed to investigate the function of PAR2 in high-fat diet-fed mice with col...
Proinflammatory cytokines inhibit thiamin uptake by human and mouse pancreatic acinar cells: involvement of transcriptional mechanism(s) [0.03%]
促炎细胞因子通过转录机制抑制硫胺素在人和小鼠胰腺泡状细胞中的吸收
Kasin Yadunandam Anandam,Padmanabhan Srinivasan,Tomoya Yasujima et al.
Kasin Yadunandam Anandam et al.
Thiamin (vitamin B1) plays critical roles in normal metabolism and function of all mammalian cells. Pancreatic acinar cells (PACs) import thiamin from circulation via specific carrier-mediated uptake that involves thiamin transporter-1 and ...
Retraction [0.03%]
撤稿通知
Retraction of Publication
American journal of physiology. Gastrointestinal and liver physiology. 2020 Nov 1;319(5):G636. DOI:10.1152/ajpgi.00161.2020 2020
Lara Ferris,Sebastian Doeltgen,Charles Cock et al.
Lara Ferris et al.
Oropharyngeal swallowing involves complex neuromodulation to accommodate changing bolus characteristics. The pressure events during deglutitive pharyngeal reconfiguration and bolus flow can be assessed quantitatively using high-resolution p...