Loss of Slfn3 induces a sex-dependent repair vulnerability after 50% bowel resection [0.03%]
Slfn3丢失在50％结肠切除术后诱导性别依赖性修复易感性
Emilie E Vomhof-DeKrey,Jack T Lansing,Diane C Darland et al.
Emilie E Vomhof-DeKrey et al.
Bowel resection accelerates enterocyte proliferation in the remaining gut with suboptimal absorptive and digestive capacity because of a proliferation-associated decrease in functional differentiation markers. We hypothesized that although ...
Sophie L Allen,Jonathan I Quinlan,Amritpal Dhaliwal et al.
Sophie L Allen et al.
Sarcopenia, a condition of low muscle mass, quality, and strength, is commonly found in patients with cirrhosis and is associated with adverse clinical outcomes including reduction in quality of life, increased mortality, and posttransplant...
Long noncoding RNA LINC00982 upregulates CTSF expression to inhibit gastric cancer progression via the transcription factor HEY1 [0.03%]
长链非编码RNA LINC00982通过转录因子HEY1上调CTSF表达抑制胃癌进展
Lei Zheng,Junlin Cao,Lijie Liu et al.
Lei Zheng et al.
Upregulating the expression of long noncoding RNA LINC00982 controlled cell proliferation in gastric cancer, but the regulatory molecular mechanisms are yet to be expounded. We here aimed to elaborate how LINC00982 regulated the malignancy ...
Parenteral lipid emulsions induce unique ileal fatty acid and metabolomic profiles but do not increase the risk of necrotizing enterocolitis in preterm pigs [0.03%]
肠外脂质乳剂诱导独特的回肠脂肪酸和代谢组谱型，但不会增加早产猪坏死性小肠结肠炎的风险
William Yakah,Pratibha Singh,Joanne Brown et al.
William Yakah et al.
Necrotizing enterocolitis (NEC) is a manifestation of maladaptive intestinal responses in preterm infants centrally medicated by unattenuated inflammation. Early in the postnatal period, preterm infants develop a deficit in arachidonic and ...
Pregnancy-related plasticity of gastric vagal afferent signals in mice [0.03%]
小鼠妊娠相关的胃迷走神经传入信号可塑性研究
Hui Li,Georgia S Clarke,Stewart Christie et al.
Hui Li et al.
Gastric vagal afferents (GVAs) sense food-related mechanical stimuli and signal to the central nervous system, to integrate control of meal termination. Pregnancy is characterized by increased maternal food intake, which is essential for no...
GPCRs get fatty: the role of G protein-coupled receptor signaling in the development and progression of nonalcoholic fatty liver disease [0.03%]
G蛋白偶联受体信号转导在非酒精性脂肪肝病发生发展中的作用：GPCRs“变胖”了
Ryan Kurtz,Meghan F Anderman,Blythe D Shepard
Ryan Kurtz
Nonalcoholic fatty liver disease (NAFLD), characterized by the abnormal deposition of lipids within the liver not due to alcohol consumption, is a growing epidemic affecting over 30% of the United States population. Both simple fatty liver ...
Musings on the wanderer: What's new in our understanding of vago-vagal reflexes? VI. Central vagal circuits that control glucose metabolism [0.03%]
游吟者沉思录：我们对迷走神经反射的新认识（六）调控葡萄糖代谢的中枢迷走神经环路
Soledad Pitra,Bret N Smith
Soledad Pitra
Neurons in the brain stem dorsal vagal complex (DVC) take part in a continuous bidirectional crosstalk, in which they receive and respond to a vast array of signaling molecules, including glucose. Importantly, chronic dysregulation of blood...
Intestinal extracellular vesicles are altered by vertical sleeve gastrectomy [0.03%]
肠细胞外囊泡在袖状胃切除术后发生改变
Andriy Myronovych,Bailey C E Peck,Mingrui An et al.
Andriy Myronovych et al.
Bariatric surgery is the most effective treatment for obesity and its comorbidities. However, our understanding of the molecular mechanisms behind its beneficial effects is limited. Extracellular vesicles (EVs) comprise an important mode of...
Assessment of esophageal body peristaltic work using functional lumen imaging probe panometry [0.03%]
应用功能性腔内影像探针评估食管体部的推进性收缩功能
Shashank Acharya,Sourav Halder,Dustin A Carlson et al.
Shashank Acharya et al.
The goal of this study was to conceptualize and compute measures of "mechanical work" done by the esophagus using data generated during functional lumen imaging probe (FLIP) panometry and compare work done during secondary peristalsis among...