Budding Baboon Blues: The Prenatal Diet Lands a Lasting Gut Punch [0.03%]
初生婴猴的肠道苦恼：母体饮食影响后代肠道菌群终身进化
Anna Grigorian,Mengyun Wu,Jerrold R Turner
Anna Grigorian
Matthew C Rowe,Victor L Pettersson,Simona Elisa Carbone et al.
Matthew C Rowe et al.
The mucus layer is an essential physical barrier that protects and lubricates mucosal surfaces in the body. The semi-permeable nature of the mucus layer limits bacterial interactions with the epithelium, while allowing nutrient absorption. ...
Treg-specific IL-6R signaling: a novel role in the regulation of the intestinal epithelium [0.03%]
特异性作用于调节性T细胞的IL-6受体信号通路在肠道上皮细胞调控中的新功能作用
Emily E Klatt,Feda H Hamdan,Isaiah Pérez et al.
Emily E Klatt et al.
Mucosal homeostasis requires coordinated immune regulation and epithelial repair. Inflammatory bowel disease (IBD) arises from disrupted coordination between the immune system and intestinal epithelium, where resolution and repair must occu...
STRESS DURING PREGNANCY ALTERS HEPATIC RENIN-ANGIOTENSIN SYSTEM AND REDOX HOMEOSTASIS IN A SEX- AND AGE-SPECIFIC MANNER [0.03%]
妊娠期压力以性别和年龄特异性的方式改变肝脏肾素血管紧张素系统和氧化还原稳态
Gabriel Fernandes Teixeira,Juliana Mentzinger,Juliana Arruda de Souza Monnerat et al.
Gabriel Fernandes Teixeira et al.
The hypothesis of the development and origin of health and disease (DOHaD) highlights the relationship between exposure to harmful stimuli during pregnancy and the increased cardiometabolic risk in the offspring's adulthood. It is believed ...
Influence of isoflurane and propofol on gastric slow wave patterns and pacing efficacy in pigs [0.03%]
异氟醚和丙泊酚对猪胃慢波模式及起搏效果的影响
Nipuni D Nagahawatte,Peng Du,Hanyu Zhang et al.
Nipuni D Nagahawatte et al.
Background and purpose: Gut motility is partly driven by underlying rhythmic electrical activity called slow waves. The origin and propagation of these electrical events are studied extensively in anesthetized animal mode...
Estanislao Peixoto,Kishor Pant,Seth Richard et al.
Estanislao Peixoto et al.
Primary cilia have been considered tumor-suppressing organelles in cholangiocarcinoma (CCA), though the mechanisms behind their protective role are not fully understood. This study investigates how the loss of primary cilia affects DNA dama...
The Synergistic Interplay between Vitamin A, Dietary Fiber, and the Microbiota-Gut-Brain Axis: A Potential Mechanism for Preventing Alzheimer's Disease [0.03%]
维生素A、膳食纤维和微生物群-肠-脑轴之间的协同作用：预防阿尔茨海默病的潜在机制
Shadt Skawratananond,Grace McCrea,Paul Lie et al.
Shadt Skawratananond et al.
The human gastrointestinal tract harbors a vast and diverse microbial community, with the gut microbiome playing a fundamental role in numerous biological processes that influence overall health and disease progression. Emerging evidence ha...
Hysteresis of the Lower Esophageal Sphincter: Relevance to the Pathogenesis of Esophageal Achalasia and its Phenotypes [0.03%]
LES低reflux屏障功能的迟发性与贲门失弛缓症及其分型发病机制的关系研究
Anand Jain,William Breaux,Joshua K Roberston et al.
Anand Jain et al.
Background & Aims: Hysteresis is a change in strain for a given repeated stress; it is a material property of the viscoelastic tissues. We aimed to determine hysteresis of the esophagogastric junction (EGJ) in patients with esophageal achal...
Cyclic infusion mitigates liver dysfunction associated with continuous total parenteral nutrition in a novel murine model [0.03%]
新型小鼠模型中周期性输注可缓解连续全肠外营养相关肝功能障碍
Nathaniel B Willis,Tahliyah S Mims,Karen Antunes et al.
Nathaniel B Willis et al.
Parenteral nutrition (PN) is a lifesaving intervention for patients unable to feed enterally but is often associated with parenteral nutrition associated liver disease (PNALD), also called intestinal failure associated liver disease (IFALD)...
Ji Yeon Kim,Sean P Colgan
Ji Yeon Kim