The Pathophysiology of Acute Lung Injury following Intestinal Ischemia-Reperfusion [0.03%]
肠缺血再灌注后急性肺损伤的发病机制
Mickael Palmier,Sylvain Fraineau,Angela Sutton et al.
Mickael Palmier et al.
Acute mesenteric ischemia is a severe and life-threatening condition with a mortality rate of up to 50%. Its treatment, which depends on the etiology, focuses on preserving intestinal viability through prompt restoration of blood flow. Whil...
The Value of Deep Inspirations [0.03%]
深吸气的价值
Gary C Sieck
Gary C Sieck
A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity [0.03%]
急性新生儿肺损伤的时空转录组图谱发育和疾病严重程度下的急性新生儿肺损伤的时空转录组图谱
Saahithi Mallapragada,Ruqian Lyu,Arianna L Williams-Katek et al.
Saahithi Mallapragada et al.
A molecular understanding of lung organogenesis requires delineation of the timing and regulation of the cellular transitions that ultimately form and support a surface capable of gas exchange. While the advent of single-cell transcriptomic...
Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium [0.03%]
,Yes相互作用蛋白诱导肺血管内皮衰老及相关炎症信号响应
Memet T Emin,Alexandra M Dubuisson,Prisha Sujin Kumar et al.
Memet T Emin et al.
Acute Lung Injury (ALI) causes the highly lethal Acute Respiratory Distress Syndrome (ARDS) in children and adults, for which therapy is lacking. Children with Pediatric ARDS (PARDS) have a mortality rate that is about half of adults with A...
A cannabinoid receptor 1 inverse agonist induces weight loss and reduces airway hyperresponsiveness in a mouse model of obese asthma [0.03%]
一种大麻素受体1反向激动剂可使肥胖哮喘小鼠模型减轻体重并降低气道高反应性
Carolyn R Morris,Ravishankar Chandrasekaran,Isabella M Butzirus et al.
Carolyn R Morris et al.
Most people with severe asthma have obesity. Metabolic dysfunction, often associated with obesity, is particularly associated with severe asthma. Mechanisms linking metabolic dysfunction with asthma, and whether improving metabolic function...
Opportunity Knocks: The 4th cohort of the American Journal of Physiology-Lung Cellular and Molecular Physiology Early Career Editorial Fellowship Program [0.03%]
机会来了！美国生理学会：肺细胞和分子生理学早期职业编辑 fellowship 第四届项目成员揭晓
Larissa A Shimoda,Cristina M Alvira,Julie A Bastarache et al.
Larissa A Shimoda et al.
High fat diet obesity exacerbates acute lung injury induced dysregulation of fatty acid oxidation in alveolar epithelial type 2 cells [0.03%]
高脂饮食引起的肥胖会加重急性肺损伤诱导的肺泡II型上皮细胞脂肪酸氧化障碍
Eleni Kallinos,Kuei-Pin Chung,Lisa K Torres et al.
Eleni Kallinos et al.
Obesity is a risk factor for acute respiratory distress syndrome (ARDS). We previously showed obesity is linked to increased lung injury and bronchoalveolar lavage fluid (BALF) fatty acids in a hyperoxic model of ARDS. We sought to expand o...
Functional modulation of retrotrapezoid neurons drives fentanyl-induced respiratory depression [0.03%]
芬太尼致呼吸抑制源于对头端吸气神经的功能调控
Thiago S Moreira,Nicholas J Burgraff,Ana C Takakura et al.
Thiago S Moreira et al.
The primary cause of death from opioid overdose is opioid-induced respiratory depression (OIRD), characterized by severe suppression of respiratory rate, destabilized breathing patterns, hypercapnia, and heightened risk of apnea. The retrot...
Mechanical Stretch Promotes Sustained Proliferation and Inflammation in Developing Human Airway Smooth Muscle [0.03%]
机械牵张促进发育中的人类气道平滑肌的持续增殖和炎症反应
Li Y Drake,Daniel Pfeffer-Kleemann,Emily Y Zhang et al.
Li Y Drake et al.
Preterm infants frequently require respiratory support, including continuous positive airway pressure (CPAP), that imposes mechanical stretch on highly compliant perinatal airways. How this excess stress impacts airway development and funct...