Karl Swann,F Anthony Lai
Karl Swann
The most fundamental unresolved issue of fertilization is to define how the sperm activates the egg to begin embryo development. Egg activation at fertilization in all species thus far examined is caused by some form of transient increase i...
Are There Deleterious Cardiac Effects of Acute and Chronic Endurance Exercise? [0.03%]
急性或慢性耐力运动会有不良的心脏影响吗？
Thijs M H Eijsvogels,Antonio B Fernandez,Paul D Thompson
Thijs M H Eijsvogels
Multiple epidemiological studies document that habitual physical activity reduces the risk of atherosclerotic cardiovascular disease (ASCVD), and most demonstrate progressively lower rates of ASCVD with progressively more physical activity....
Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility [0.03%]
环境和遗传易感性对男性生殖障碍及生育趋势的影响
Niels E Skakkebaek,Ewa Rajpert-De Meyts,Germaine M Buck Louis et al.
Niels E Skakkebaek et al.
It is predicted that Japan and European Union will soon experience appreciable decreases in their populations due to persistently low total fertility rates (TFR) below replacement level (2.1 child per woman). In the United States, where TFR...
Dane Parker,Danielle Ahn,Taylor Cohen et al.
Dane Parker et al.
Health care-associated bacterial pneumonias due to multiple-drug resistant (MDR) pathogens are an important public health problem and are major causes of morbidity and mortality worldwide. In addition to antimicrobial resistance, these orga...
Michael D Griswold
Michael D Griswold
Mammalian spermatogenesis requires a stem cell pool, a period of amplification of cell numbers, the completion of reduction division to haploid cells (meiosis), and the morphological transformation of the haploid cells into spermatozoa (spe...
Murali Prakriya,Richard S Lewis
Murali Prakriya
Store-operated calcium channels (SOCs) are a major pathway for calcium signaling in virtually all metozoan cells and serve a wide variety of functions ranging from gene expression, motility, and secretion to tissue and organ development and...
Elizabeth W Bradley,Lomeli R Carpio,Andre J van Wijnen et al.
Elizabeth W Bradley et al.
Histone deacetylases (Hdacs) are conserved enzymes that remove acetyl groups from lysine side chains in histones and other proteins. Eleven of the 18 Hdacs encoded by the human and mouse genomes depend on Zn(2+) for enzymatic activity, whil...
Aquaporins in Plants [0.03%]
植物中的水通道蛋白
Christophe Maurel,Yann Boursiac,Doan-Trung Luu et al.
Christophe Maurel et al.
Aquaporins are membrane channels that facilitate the transport of water and small neutral molecules across biological membranes of most living organisms. In plants, aquaporins occur as multiple isoforms reflecting a high diversity of cellul...
Jonathan H Widdicombe,Jeffrey J Wine
Jonathan H Widdicombe
Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B, and hundreds of different proteins with diverse protective fu...
Sandra T Cooper,Paul L McNeil
Sandra T Cooper
Eukaryotic cells have been confronted throughout their evolution with potentially lethal plasma membrane injuries, including those caused by osmotic stress, by infection from bacterial toxins and parasites, and by mechanical and ischemic st...