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期刊名:Physiological reviews

缩写:PHYSIOL REV

ISSN:0031-9333

e-ISSN:1522-1210

IF/分区:28.7/Q1

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Tao Yang,Bart O Williams Tao Yang
The identification of the low-density lipoprotein receptor (LDLR) provided a foundation for subsequent studies in lipoprotein metabolism, receptor-mediated endocytosis, and many other fundamental biological functions. The importance of the ...
Paul J Baker,Dominic De Nardo,Fiona Moghaddas et al. Paul J Baker et al.
Cell surface innate immune receptors can directly detect a variety of extracellular pathogens to which cytoplasmic innate immune sensors are rarely exposed. Instead, within the cytoplasm, the environment is rife with cellular machinery and ...
Bernardo Rodriguez-Iturbe,Hector Pons,Richard J Johnson Bernardo Rodriguez-Iturbe
High blood pressure is present in more than one billion adults worldwide and is the most important modifiable risk factor of death resulting from cardiovascular disease. While many factors contribute to the pathogenesis of hypertension, a r...
Nicholas Stafford,Claire Wilson,Delvac Oceandy et al. Nicholas Stafford et al.
The Ca2+ extrusion function of the four mammalian isoforms of the plasma membrane calcium ATPases (PMCAs) is well established. There is also ever-increasing detail known of their roles in global and local Ca2+ homeostasis and intracellular ...
Jean-Francois Arnal,Françoise Lenfant,Raphaël Metivier et al. Jean-Francois Arnal et al.
Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a key role in reproduction and exerting functions in numerous nonreproductive tissues. In this review, we attempt to summarize the in vitro studies that a...
Paul S Cooke,Manjunatha K Nanjappa,CheMyong Ko et al. Paul S Cooke et al.
Estrogens have historically been associated with female reproduction, but work over the last two decades established that estrogens and their main nuclear receptors (ESR1 and ESR2) and G protein-coupled estrogen receptor (GPER) also regulat...
Rodrigo S Lacruz,Stefan Habelitz,J Timothy Wright et al. Rodrigo S Lacruz et al.
Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate species and provides maximum durability that allows teeth to function as weapons and/or tools as well as for food processing. Enamel development and m...
Philipp Gut,Sven Reischauer,Didier Y R Stainier et al. Philipp Gut et al.
The burden of cardiovascular and metabolic diseases worldwide is staggering. The emergence of systems approaches in biology promises new therapies, faster and cheaper diagnostics, and personalized medicine. However, a profound understanding...
Josep Dalmau,Christian Geis,Francesc Graus Josep Dalmau
Investigations in the last 10 years have revealed a new category of neurological diseases mediated by antibodies against cell surface and synaptic proteins. There are currently 16 such diseases all characterized by autoantibodies against ne...