Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility [0.03%]
纤溶酶(原)升高是感染SARS-CoV-2的危险因素
Hong-Long Ji,Runzhen Zhao,Sadis Matalon et al.
Hong-Long Ji et al.
Patients with hypertension, diabetes, coronary heart disease, cerebrovascular illness, chronic obstructive pulmonary disease, and kidney dysfunction have worse clinical outcomes when infected with SARS-CoV-2, for unknown reasons. The purpos...
Impact of Respiratory Syncytial Virus Infection on Host Functions: Implications for Antiviral Strategies [0.03%]
呼吸道合胞病毒感染对宿主功能的影响及其抗病毒策略意义
MengJie Hu,Marie A Bogoyevitch,David A Jans
MengJie Hu
Respiratory syncytial virus (RSV) is one of the leading causes of viral respiratory tract infection in infants, the elderly, and the immunocompromised worldwide, causing more deaths each year than influenza. Years of research into RSV since...
Sonja Kleinlogel,Christian Vogl,Marcus Jeschke et al.
Sonja Kleinlogel et al.
Impairments of vision and hearing are highly prevalent conditions limiting the quality of life and presenting a major socioeconomic burden. For a long time, retinal and cochlear disorders have remained intractable for causal therapies, with...
Marianela G Dalghi,Nicolas Montalbetti,Marcelo D Carattino et al.
Marianela G Dalghi et al.
The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra, forms a high-resistance but adaptable barrier that surveils its mechanochemical environment and communicates changes to underlying tissues includi...
Ion Channels Controlling Circadian Rhythms in Suprachiasmatic Nucleus Excitability [0.03%]
视交叉上核兴奋性昼夜节律的离子通道控制机制
Jenna R M Harvey,Amber E Plante,Andrea L Meredith
Jenna R M Harvey
Animals synchronize to the environmental day-night cycle by means of an internal circadian clock in the brain. In mammals, this timekeeping mechanism is housed in the suprachiasmatic nucleus (SCN) of the hypothalamus and is entrained by lig...
Revisiting the Functional Anatomy of the Human Brain: Toward a Meta-Networking Theory of Cerebral Functions [0.03%]
人脑功能解剖的再思考——向大脑功能元联网理论发展
Guillaume Herbet,Hugues Duffau
Guillaume Herbet
For more than one century, brain processing was mainly thought in a localizationist framework, in which one given function was underpinned by a discrete, isolated cortical area, and with a similar cerebral organization across individuals. H...
Hilary O D Critchley,Jacqueline A Maybin,Gregory M Armstrong et al.
Hilary O D Critchley et al.
The physiological functions of the uterine endometrium (uterine lining) are preparation for implantation, maintenance of pregnancy if implantation occurs, and menstruation in the absence of pregnancy. The endometrium thus plays a pivotal ro...
From Ancient to Emerging Infections: The Odyssey of Viruses in the Male Genital Tract [0.03%]
从古到今：男性生殖道病毒的演变_odyssey病毒之旅
Anna Le Tortorec,Giulia Matusali,Dominique Mahé et al.
Anna Le Tortorec et al.
The male genital tract (MGT) is the target of a number of viral infections that can have deleterious consequences at the individual, offspring, and population levels. These consequences include infertility, cancers of male organs, transmiss...
Phylogenic Determinants of Cardiovascular Frailty, Focus on Hemodynamics and Arterial Smooth Muscle Cells [0.03%]
心血管脆弱的谱系决定因素，重点是血液动力学和动脉平滑肌细胞
Jean-Baptiste Michel
Jean-Baptiste Michel
The evolution of the circulatory system from invertebrates to mammals has involved the passage from an open system to a closed in-parallel system via a closed in-series system, accompanying the increasing complexity and efficiency of life's...
Jens Leipziger,Helle Praetorius
Jens Leipziger
Autocrine and paracrine signaling in the kidney adds an extra level of diversity and complexity to renal physiology. The extensive scientific production on the topic precludes easy understanding of the fundamental purpose of the vast number...