Wonder of wonders, miracle of miracles: the unprecedented speed of COVID-19 science [0.03%]
奇迹中的奇迹：COVID-19科学研究的空前速度
Michael Saag
Michael Saag
Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs [0.03%]
氢化硫在哺乳动物细胞、组织和器官中的生理作用
Giuseppe Cirino,Csaba Szabo,Andreas Papapetropoulos
Giuseppe Cirino
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous regulator of a broad range of physiological functions. H2S belongs to the class of molecules known as gasotransmitters, which typically include nitric oxide (NO)...
Albumin uptake and processing by the proximal tubule: physiological, pathological, and therapeutic implications [0.03%]
白蛋白的重吸收及处理：生理、病理及治疗意义
Bruce A Molitoris,Ruben M Sandoval,Shiv Pratap S Yadav et al.
Bruce A Molitoris et al.
For nearly 50 years the proximal tubule (PT) has been known to reabsorb, process, and either catabolize or transcytose albumin from the glomerular filtrate. Innovative techniques and approaches have provided insights into these processes. S...
Evolutionarily conserved transcription factors as regulators of longevity and targets for geroprotection [0.03%]
长寿调节因子和抗衰老靶点的保守转录因子
Fabian Fischer,Giovanna Grigolon,Christoph Benner et al.
Fabian Fischer et al.
Aging is the single largest risk factor for many debilitating conditions, including heart diseases, stroke, cancer, diabetes, and neurodegenerative disorders. Although far from understood in its full complexity, it is scientifically well es...
Rebecca M Reynolds,Sarah J Stock,Fiona C Denison et al.
Rebecca M Reynolds et al.
Alejandro M Chibly,Marit H Aure,Vaishali N Patel et al.
Alejandro M Chibly et al.
Salivary glands produce and secrete saliva, which is essential for maintaining oral health and overall health. Understanding both the unique structure and physiological function of salivary glands, as well as how they are affected by diseas...
Carol Ann Remme
Carol Ann Remme
ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum [0.03%]
自噬体介导的内质网溶酶体清除：机制、调节及其与人类疾病的关系
Fulvio Reggiori,Maurizio Molinari
Fulvio Reggiori
ER-phagy (reticulophagy) defines the degradation of portions of the endoplasmic reticulum (ER) within lysosomes or vacuoles. It is part of the self-digestion (i.e., autophagic) programs recycling cytoplasmic material and organelles, which r...
Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology [0.03%]
碳酸酐酶在动物模型生物中的研究：分子、机制和生理学
Ashok Aspatwar,Martti E E Tolvanen,Harlan Barker et al.
Ashok Aspatwar et al.
During the past three decades, mice, zebrafish, fruit flies, and Caenorhabditis elegans have been the primary model organisms used for the study of various biological phenomena. These models have also been adopted and developed to investiga...
The physiological sensor channels TRP and piezo: Nobel Prize in Physiology or Medicine 2021 [0.03%]
生理传感器通道TRP和Piezo：2021年诺贝尔生理学或医学奖
Scott Earley,L Fernando Santana,W Jonathan Lederer
Scott Earley
Keywords: Nobel Prize; Piezo channels; TRP channels; pressure; temperature.