Leveraging physiology and artificial intelligence to deliver advancements in health care [0.03%]
利用生理学和人工智能推动医疗卫生事业的发展
Angela Zhang,Zhenqin Wu,Eric Wu et al.
Angela Zhang et al.
Artificial intelligence in health care has experienced remarkable innovation and progress in the last decade. Significant advancements can be attributed to the utilization of artificial intelligence to transform physiology data to advance h...
John S Harrington,Stefan W Ryter,Maria Plataki et al.
John S Harrington et al.
Mitochondria are well known as organelles responsible for the maintenance of cellular bioenergetics through the production of ATP. Although oxidative phosphorylation may be their most important function, mitochondria are also integral for t...
Robert L Chevalier
Robert L Chevalier
Chronic kidney disease (CKD) affects >10% of the world population, with increasing prevalence in middle age. The risk for CKD is dependent on the number of functioning nephrons through the life cycle, and 50% of nephrons are lost through no...
The human periconceptional maternal-embryonic space in health and disease [0.03%]
人类围受精期母胎界面在健康和疾病中的作用
Inmaculada Moreno,Antonio Capalbo,Aymara Mas et al.
Inmaculada Moreno et al.
Pregnancy is established during the periconceptional period as a continuum beginning with blastocyst attachment to the endometrial epithelial surface followed by embryo invasion and placenta formation. This period sets the foundation for th...
Membrane adhesion junctions regulate airway smooth muscle phenotype and function [0.03%]
气道平滑肌粘附连接调节表型和功能
Wenwu Zhang,Yidi Wu,Susan J Gunst
Wenwu Zhang
The local environment surrounding airway smooth muscle (ASM) cells has profound effects on the physiological and phenotypic properties of ASM tissues. ASM is continually subjected to the mechanical forces generated during breathing and to t...
Long-term variability of human health-related solar ultraviolet-B radiation doses for the 1980s to the end of the 21st century [0.03%]
1980年至21世纪末与人类健康相关的太阳能UVB辐射的长期变化特征
Christos Zerefos,Ilias Fountoulakis,Kostas Eleftheratos et al.
Christos Zerefos et al.
Solar ultraviolet-B (UV-B) radiation has played a crucial role in the evolution of life on Earth, and potential changes in its levels could affect the health and functionality of humans and the ecosystems. UV exposure presents both risks an...
The intercalated disc: a unique organelle for electromechanical synchrony in cardiomyocytes [0.03%]
缝隙连接：心肌细胞机电同步的特有器官
Morten S Nielsen,Chantal J M van Opbergen,Toon A B van Veen et al.
Morten S Nielsen et al.
The intercalated disc (ID) is a highly specialized structure that connects cardiomyocytes via mechanical and electrical junctions. Although described in some detail by light microscopy in the 19th century, it was in 1966 that electron micro...
Aarti Jagannath,Lewis Taylor,Yining Ru et al.
Aarti Jagannath et al.
Salt-inducible kinases (SIKs), which comprise a family of three homologous serine-threonine kinases, were first described for their role in sodium sensing but have since been shown to regulate multiple aspects of physiology. These kinases a...
Mesenchymal condensation in tooth development and regeneration: a focus on translational aspects of organogenesis [0.03%]
牙齿发育与再生中的间充质浓缩现象：专注于器官发生过程的转化方面
Bing-Dong Sui,Chen-Xi Zheng,Wan-Min Zhao et al.
Bing-Dong Sui et al.
The teeth are vertebrate-specific, highly specialized organs performing fundamental functions of mastication and speech, the maintenance of which is crucial for orofacial homeostasis and is further linked to systemic health and human psycho...
Roddy Walsh,Sean J Jurgens,Jeanette Erdmann et al.
Roddy Walsh et al.
Genome-wide association studies (GWAS) aim to identify common genetic variants that are associated with traits and diseases. Since 2005, more than 5,000 GWAS have been published for almost as many traits. These studies have offered insights...