Umar Raza,Xiaolong Tang,Zuojun Liu et al.
Umar Raza et al.
Aging is a chronic yet natural physiological decline of the body. Throughout life, humans are continuously exposed to a variety of exogenous and endogenous stresses, which engender various counteractive responses at the cellular, tissue, or...
New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN [0.03%]
非典型钠漏通道NALCN的生理和病理生理的新见解
Arnaud Monteil,Nathalie C Guérineau,Antonio Gil-Nagel et al.
Arnaud Monteil et al.
Cell excitability and its modulation by hormones and neurotransmitters involve the concerted action of a large repertoire of membrane proteins, especially ion channels. Unique complements of coexpressed ion channels are exquisitely balanced...
Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing [0.03%]
心肌梗死后间充质基质细胞改善心脏功能的时机问题
Stéphanie Barrère-Lemaire,Anne Vincent,Christian Jorgensen et al.
Stéphanie Barrère-Lemaire et al.
Acute myocardial infarction (AMI) is the leading cause of cardiovascular death and remains the most common cause of heart failure. Reopening of the occluded artery, i.e., reperfusion, is the only way to save the myocardium. However, the exp...
Michael John Patton,Amit Gaggar,Matthew Might et al.
Michael John Patton et al.
The role of quality metrics in the evolution of AI in health care and implications for generative AI [0.03%]
质量指标在医疗保健领域人工智能发展中的作用以及对生成式人工智能的启示
Ryan C Godwin,Ryan L Melvin
Ryan C Godwin
Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract [0.03%]
间质细胞中的钙信号动力学：消化道运动模式的基础机制
Kenton M Sanders,Bernard T Drumm,Caroline A Cobine et al.
Kenton M Sanders et al.
The gastrointestinal (GI) tract displays multiple motor patterns that move nutrients and wastes through the body. Smooth muscle cells (SMCs) provide the forces necessary for GI motility, but interstitial cells, electrically coupled to SMCs,...
Ron Balczon,Mike T Lin,Sarah Voth et al.
Ron Balczon et al.
Lung endothelia in the arteries, capillaries, and veins are heterogeneous in structure and function. Lung capillaries in particular represent a unique vascular niche, with a thin yet highly restrictive alveolar-capillary barrier that optimi...
Osama F Harraz,Eric Delpire
Osama F Harraz
Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms [0.03%]
血压调节和高血压的性别差异：肾脏、血液动力学和激素机制
Erika R Drury,Jing Wu,Joseph C Gigliotti et al.
Erika R Drury et al.
The teleology of sex differences has been argued since at least as early as Aristotle's controversial Generation of Animals more than 300 years BC, which reflects the sex bias of the time to contemporary readers. Although the question "why ...
Obstructive nephropathy and molecular pathophysiology of renal interstitial fibrosis [0.03%]
阻塞性肾病及肾间质纤维化的分子病理生理学
Rikke Nørregaard,Henricus A M Mutsaers,Jørgen Frøkiær et al.
Rikke Nørregaard et al.
The kidneys play a key role in maintaining total body homeostasis. The complexity of this task is reflected in the unique architecture of the organ. Ureteral obstruction greatly affects renal physiology by altering hemodynamics, changing gl...