Activated CD4+ T cells upregulate PD-L1 expression on B cells through CD40/CD40L signaling and direct contact in systemic lupus erythematosus [0.03%]
系统性红斑狼疮中活化的CD4+T细胞通过CD40/CD40L信号传导和直接接触上调B细胞PD-L1的表达
Siyuan Lai,Ning Li,Songyue Chen et al.
Siyuan Lai et al.
Programmed cell death protein 1 (PD-1) expression on T cells has been implicated in the pathogenesis of autoimmune diseases; however, the functional role of programmed death-ligand 1 (PD-L1) expression on B cells remains insufficiently char...
ProBNP, cytokines, and the Nrf2/HO-1 signaling pathway: A cross-sectional study on cardiovascular risk in rheumatoid arthritis [0.03%]
风湿性关节炎心血管风险的横断面研究：利钠肽、细胞因子与Nrf2/HO-1信号通路的关系
Christiane Aguiar Nobre,Carlos Ewerton Maia Rodrigues,Natacha Xavier Cavalcante et al.
Christiane Aguiar Nobre et al.
We evaluated associations between clinical/laboratory findings and serum cytokines, Nrf2/HO-1 pathway expression and cardiovascular risk in both RA patients and controls. Sixty RA patients and 60 controls were included in the study. Serum c...
Differential control of mycobacterial growth ex vivo by COVID-19 patients is associated with CD8+ CD28+ T cells [0.03%]
COVID-19患者体外分枝杆菌生长的差异控制与CD8+CD28+T细胞相关
Alba Llibre,Henna Siddiqui,Julie G Burel et al.
Alba Llibre et al.
Diseases caused by SARS-CoV-2 and Mycobacterium tuberculosis (M.tb) represent two public health emergencies. In severe presentations of disease, both pathogens may share a biological niche in the lower respiratory tract. There is significan...
Oral microbiota in allergic diseases, and sublingual allergen immunotherapy [0.03%]
过敏性疾病口腔微生物群及舌下免疫疗法
Umut Gazi,Nerin Nadir Bahceciler
Umut Gazi
Allergic diseases with their epidemic prevalence on the rise have been one of the major global health problems of the 21st century. The association of increased prevalence with lifestyle changes including increased urbanization, and hygiene...
Frequency of the AC-2 pattern's new variant (AC-30) and detection of different immunological relationships [0.03%]
AC-2模式新变异型(AC-30)的流行率及不同免疫学关系的检测
Mehmet Akif Durmuş,Selda Kömeç
Mehmet Akif Durmuş
Aim: This study investigates the frequency and autoantibody profile of the newly defined AC-30 pattern, a variant of the AC-2 dense fine speckled pattern, in patients undergoing antinuclear antibodies (ANA) testing via II...
Clinical characteristics, risk factors and predictors of Parvovirus B19 infection in patients with autoimmune rheumatic inflammatory diseases: A nested case-control study [0.03%]
自身免疫风湿性疾病患者B19病毒感染的临床特点、危险因素及预测指标：例证研究
Xinyue Zhang,Peixuan Liang,Ziwei Hu et al.
Xinyue Zhang et al.
This nested case-control study explored the clinical features and risk factors of Parvovirus B19 (B19V) infection in autoimmune rheumatic inflammatory disease (AIIRD) patients. A total of 86 B19V-positive cases and 172 matched controls were...
PD-1 monoclonal antibody (Tislelizumab)-induced DRESS syndrome in an intrahepatic cholangiocarcinoma patient with FGFR3 mutation and elevated IgG4:A case report [0.03%]
携带FGFR3突变和IgG4升高的肝内胆管癌患者发生PD-1单克隆抗体（替雷利珠单抗）致DRESS综合征一例报告
Wei Qin,Xiaoying Wu,Qiongyuan Xu et al.
Wei Qin et al.
Background: Immune-related adverse events (irAEs) include a rare, idiosyncratic but potentially life-threatening drug reaction with eosinophilia and systemic symptoms (DRESS), characterized by exanthem, fever, as well as ...
Increased levels of Foxp3+CD4+NKT-like cells are associated with HIV disease progression [0.03%]
Foxp3+CD4+NKT样细胞水平升高与HIV疾病进展有关
Na Chen,Leidan Zhang,Xinyue Wang et al.
Na Chen et al.
Persistent immune activation is a key factor contributing to AIDS progression and non-AIDS-associated complications. NKT-like cells were found to exert immunosuppressive roles under some pathological situations by Foxp3 upregulation. Here, ...
Proteomic profiling of serum small extracellular vesicles predicts post-COVID syndrome development [0.03%]
血清小细胞外囊泡的蛋白质组学谱型可以预测新冠后遗症的发展
Gabriella Dobra,Edina Gyukity-Sebestyen,Matyas Bukva et al.
Gabriella Dobra et al.
Post-COVID syndrome affects 10-35 % of COVID-19 patients, and up to 85 % of hospitalized individuals, underscoring the need for early identification of high-risk cases. We hypothesized that the proteomic profile of serum small extracellular...