Assessing and managing risks arising from exposure to endocrine-active chemicals [0.03%]
内分泌活性化学物质接触产生的风险的评估和管理
Karen P Phillips,Warren G Foster,William Leiss et al.
Karen P Phillips et al.
Managing risks to human health and the environment produced by endocrine-active chemicals (EAC) is dependent on sound principles of risk assessment and risk management, which need to be adapted to address the uncertainties in the state of t...
Risk communication of endocrine-disrupting chemicals: improving knowledge translation and transfer [0.03%]
内分泌干扰物的风险交流：改善知识转化和转移
Michael G Tyshenko,Karen P Phillips,Michael Mehta et al.
Michael G Tyshenko et al.
Public perception of the negative effects of endocrine-disrupting chemicals appears to be higher compared to other chemical pollutants, due to (1) chronic, low-probability effects, and (2) uncertainties about which biological effects may be...
Karen P Phillips,Warren G Foster
Karen P Phillips
Environmental etiologies involving exposures to chemicals that mimic endogenous hormones are proposed for a number of adverse human health effects, including infertility, abnormal prenatal and childhood development, and reproductive cancers...
Risk factors for ovarian cancer: an overview with emphasis on hormonal factors [0.03%]
卵巢癌的危险因素：以激素因素为重点的概述
Fariba Salehi,Lesley Dunfield,Karen P Phillips et al.
Fariba Salehi et al.
Ovarian cancer is the fifth most frequently occurring cancer among women and leading cause of gynecological cancer deaths in North America. Although the etiology of ovarian cancer is not clear, certain factors are implicated in the etiology...
Review of the etiology of breast cancer with special attention to organochlorines as potential endocrine disruptors [0.03%]
内分泌干扰物与乳腺癌发病机制的关系——重点关注有机氯类化合物的影响
Fariba Salehi,Michelle C Turner,Karen P Phillips et al.
Fariba Salehi et al.
Breast cancer is the most frequently diagnosed cancer among Canadian women, accounting for about 30% of all new cancer cases each year. Although the incidence of breast cancer has increased over the past 50 years, the cause of this rise is ...
Michael Garner,Michelle C Turner,Parviz Ghadirian et al.
Michael Garner et al.
Testicular cancer (TC) is a rare form of cancer, accounting for 1% of all new cancer cases in Canadian males. TC is the most common malignancy among young men, aged 25-34 yr old. Over previous decades, the incidence of TC has increased in m...
Donald T Wigle,Michelle C Turner,James Gomes et al.
Donald T Wigle et al.
American men have a lifetime risk of about 18% for prostate cancer diagnosis. Large international variations in prostate cancer risks and increased risks among migrants from low- to high-risk countries indicate important roles for environme...
The influence of the environment and other exogenous agents on spontaneous abortion risk [0.03%]
环境及其他外源性因素对自然流产风险的影响
Mandy Weselak,Tye E Arbuckle,Mark C Walker et al.
Mandy Weselak et al.
It is estimated that close to 30% of all pregnancies end in spontaneous abortion. Although about 60% of spontaneous abortions are thought to be due to genetic, infectious, hormonal, and immunological factors, the role of the environment rem...
Karen P Phillips,Nongnuj Tanphaichitr
Karen P Phillips
Reproductive pathology in the male represents about 20% of infertility cases. Male infertility may be attributed to a number of causes, including genetic and congenital abnormalities, infection, multisystemic diseases, varicocele, and other...
Endocrine toxicants including 2,3,7,8-terachlorodibenzo-p-dioxin (TCDD) and dioxin-like chemicals and endometriosis: is there a link? [0.03%]
内分泌毒物(包括2，3，7，8-四氯代二苯并对二噁英(TCDD)和类似二噁英的化学物质)与子宫内膜异位症：有联系吗？
Warren G Foster
Warren G Foster
Endometriosis is a common gynecologic disease of unknown etiology affecting approximately 10-15% of women of reproductive age and 50% of infertile women. Estrogen dependence and immune modulation are established features of endometriosis bu...