Database for physiologically based pharmacokinetic (PBPK) modeling: physiological data for healthy and health-impaired elderly [0.03%]
基于生理的药代动力学(PBPK)建模数据库:健康和功能受损老年人的生理数据
Chad M Thompson,Douglas O Johns,Babasaheb Sonawane et al.
Chad M Thompson et al.
Physiologically based pharmacokinetic (PBPK) models have increasingly been employed in chemical health risk assessments. By incorporating individual variability conferred by genetic polymorphisms, health conditions, and physiological change...
Re: Guyton, Kathryn Z., Barone, Stanley, Jr., Brown, Rebecca C., Euling, Susan Y., Jinot, Jennifer, Makris, Susan (2008). Mode of action frameworks: a critical analysis. Journal of Toxicology and Environmental Health, Part B, 11(1): 16-31 [0.03%]
关于Guyton KZ等人对模式作用途径框架进行批判性分析的评论文章摘要
M E Meek,Colin Berry,Alan R Boobis et al.
M E Meek et al.
Potential for early-life immune insult including developmental immunotoxicity in autism and autism spectrum disorders: focus on critical windows of immune vulnerability [0.03%]
自闭症和自闭症谱系障碍中包括发育免疫毒性的早期生命免疫损伤的潜在作用:关注免疫脆弱的关键窗口
Rodney R Dietert,Janice M Dietert
Rodney R Dietert
Early-life immune insults (ELII) including xenobiotic-induced developmental immunotoxicity (DIT) are important factors in childhood and adult chronic diseases. However, prenatal and perinatal environmentally induced immune alterations have ...
Human biomonitoring and the INSPIRE directive: spatial data as link for environment and health research [0.03%]
人类生物监测和INSPIRE指令:空间数据作为环境与健康研究的纽带
Roel Smolders,Ludwine Casteleyn,Reinhard Joas et al.
Roel Smolders et al.
Recently, there has been a rapid gain of interest in the availability, applicability, and integration of different types of spatial data for environment and health issues. The INSPIRE Directive (Directive 2007/2/EC) aims at providing better...
A review of the immunotoxicity of the pesticide 3,4-dichloropropionanalide [0.03%]
3,4-二氯丙酮醛的免疫毒性的评述
Keith D Salazar,Irina V Ustyugova,Kathleen M Brundage et al.
Keith D Salazar et al.
The pesticide 3,4-dichloropropionanilide (propanil or, alternatively, DCPA) is a member of the acetanilide chemical family and is predominantly used for the control of weeds on commercial rice crops worldwide. This article was written to pr...
Joachim D Pleil
Joachim D Pleil
As a discipline of public health, environmental health science is the study of the linkage from environmental pollution sources to eventual adverse health outcome. This progression may be divided into two components, (1) "exposure assessmen...
Re: Ritter, Leonard, Totman, Celine, Krishnan, Kannan, Carrier, Richard, Vezina, Anne, Morisset, Veronique. (2007). Deriving uncertainty factors for threshold chemical contaminants in drinking water. Journal of Toxicology and Environmental Health, Part B, 10:527-557 [0.03%]
里特,伦纳德,托特曼,塞莉恩,克里希南,卡南,凯瑞,理查德,维日娜,安妮,莫里塞,维尔若尼。《饮用水中阈值化学污染物不确定性的研究》
R Konietzka,H H Dieter,K Schneider
R Konietzka
State-of-the-science review of the occupational health hazards of crystalline silica in abrasive blasting operations and related requirements for respiratory protection [0.03%]
磨料喷砂作业中结晶态二氧化硅的职业健康危害及呼吸防护相关要求的科学评价
Amy K Madl,Ellen P Donovan,Shannon H Gaffney et al.
Amy K Madl et al.
Excessive exposures to airborne crystalline silica have been known for over 100 years to pose a serious health hazard. Work practices and regulatory standards advanced as the knowledge of the hazards of crystalline silica evolved. This arti...
Approaches for applications of physiologically based pharmacokinetic models in risk assessment [0.03%]
基于生理的药代动力学模型在风险评估中的应用方法
Chad M Thompson,Babasaheb Sonawane,Hugh A Barton et al.
Chad M Thompson et al.
Physiologically based pharmacokinetic (PBPK) models are particularly useful for simulating exposures to environmental toxicants for which, unlike pharmaceuticals, there is often little or no human data available to estimate the internal dos...
Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants [0.03%]
环境化学污染物与生殖和儿童健康结局之间关系的流行病学证据
Donald T Wigle,Tye E Arbuckle,Michelle C Turner et al.
Donald T Wigle et al.
This review summarizes the level of epidemiologic evidence for relationships between prenatal and/or early life exposure to environmental chemical contaminants and fetal, child, and adult health. Discussion focuses on fetal loss, intrauteri...