Database-calibrated toxicity values for human health assessment based on existing toxicology data for one thousand chemicals [0.03%]
基于现有毒理学数据的千种化学品人类健康风险评估毒性参数数据库校准值的研究
Alison H Harrill,Shintaro Hagiwara,Chelsea A Weitekamp et al.
Alison H Harrill et al.
The US Environmental Protection Agency (US EPA) and other regulatory agencies routinely assess whether certain chemical exposures might result in harmful health effects. Traditional human health assessments rely upon expert judgment of dose...
Human biomonitoring and environmental health: a critical review of global exposure patterns, methodological challenges and research gaps [0.03%]
人体生物监测与环境健康：全球暴露模式、方法论挑战及研究空白的批判性回顾
Eduardo de Paula Nunes,Badr Abou Dehn Pestana,Boscolli Barbosa Pereira
Eduardo de Paula Nunes
Human biomonitoring (HBM) is an essential approach for assessing exposure to environmental toxicants and for informing risk assessment frameworks. However, the global expansion of HBM has (1) outpaced efforts to harmonize methodologies, (2)...
Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs) [0.03%]
一组新型方法（NAM）测试全氟和多氟烷基物质（PFAS）库的见解
Grace Patlewicz,Richard Judson,Katie Paul Friedman et al.
Grace Patlewicz et al.
Per- and polyfluoroalkyl substances (PFAS) comprise a large class of human-made chemicals that are in widespread use and present concerns for persistence, bioaccumulation and toxicity. Whilst a handful of PFAS have been characterized for th...
Critical review of the association between environmental manganese and thyroid function, with implications for potential neurodevelopmental effects [0.03%]
环境锰与甲状腺功能关系的批判性评价及其对神经发育影响的启示
N Karyakina,N Shilnikova,N Farhat et al.
N Karyakina et al.
Manganese (Mn) is an essential trace element that, in excess, may initiate adverse health effects. Recent evidence suggested that environmental exposure to Mn may produce thyroid hormone imbalances leading to adverse neurodevelopmental outc...
T G Osimitz,W Droege
T G Osimitz
Quaternary ammonium compounds (QACs) are widely used to kill pathogenic microbes (including COVID-19), providing a substantial public health benefit. This review is an update to our previous publications that summarized and interpreted the ...
Jie Wang,Pengfei Guo,Yanfei Bian et al.
Jie Wang et al.
Morphine has been widely used to treat physical non-cancer pain as well as cancer-related pain. However, a growing body of evidence has emerged indicating that morphine in addition to alleviating pain initiates and suppresses immune functio...
The biological and sociological implications of diversity, equity, and inclusion (DEI): life within microbiomes and on earth [0.03%]
生物多样性、公平性和包容性(DEI)的生物学和社会学含义：微生物组内的生命和地球上的生命
David A Lawrence,Brandon O&#x;Sullivan,Joerg Graf et al.
David A Lawrence et al.
From a biological point of view, Diversity, Equity, and Inclusion (DEI) are important at multiple levels, which include our genetics, microbiomes, diets, and all organ system interactions. Considering only DEI's sociological aspects is equi...
Hazard classification of manganese salts based on animal neurotoxicity data: case study for specific target organ toxicity - repeated exposure (STOT-RE) [0.03%]
基于动物神经毒性的数据的锰盐危害分类：特定目标器官毒性-反复曝光（STOT-RE）的案例研究
David C Dorman,Doreen McGough,Michael Aschner et al.
David C Dorman et al.
Specific Target Organ Toxicity - Repeated Exposure (STOT-RE) is a hazard class in both Globally Harmonized System and Classification, Labelling and Packaging (CLP) Regulation in the European Union (EU) legislation on hazard classification l...
Acute and repeated exposure toxicity of the insecticide sulfoxaflor on hymenopteran pollinators; sulfoxaflor environmental science review part III [0.03%]
杀虫剂磺啶嘧菌胺对膜翅目传粉昆虫的急性与重复暴露毒性：环保科学综述第三部分
J R Purdy,K R Solomon,V J Kramer et al.
J R Purdy et al.
To support regulatory risk assessment, standardized laboratory tests of toxicity to representative species including honeybees (Apis mellifera L.), orchard bees (Osmia spp.), and bumblebees (Bombus spp.) provide the benchmark toxicity value...