Julie E Goodman,Laura E Kerper,Robyn L Prueitt et al.
Julie E Goodman et al.
The association between perineal talc use and ovarian cancer has been evaluated in several epidemiology studies. Some case-control studies reported weak positive associations, while other case-control and three large prospective cohort inve...
A review of hepatic nanotoxicology - summation of recent findings and considerations for the next generation of study designs [0.03%]
肝纳米毒理学综述——近期研究结果总结及下一代研究设计考量
Ali Kermanizadeh,Leagh G Powell,Vicki Stone
Ali Kermanizadeh
The liver is one of the most important multi-functional organs in the human body. Amongst various crucial functions, it is the main detoxification center and predominantly implicated in the clearance of xenobiotics potentially including par...
Challenges and cares to promote rational use of chloroquine and hydroxychloroquine in the management of coronavirus disease 2019 (COVID-19) pandemic: a timely review [0.03%]
促进羟氯喹合理使用以应对新冠肺炎疫情的挑战与关照：及时的述评
Boscolli Barbosa Pereira
Boscolli Barbosa Pereira
As a result of the 2019 coronavirus disease pandemic (COVID-19), there has been an urgent worldwide demand for treatments. Due to factors such as history of prescription for other infectious diseases, availability, and relatively low cost, ...
Endogenous doesn't always mean innocuous: a scoping review of iron toxicity by inhalation [0.03%]
内生的并不总是无害的：吸入性铁毒性的综述研究
Jody Morgan,Robin Bell,Alison L Jones
Jody Morgan
Ambient air pollution is a leading risk factor for the global burden of disease. One possible pathway of particulate matter (PM)-induced toxicity is through iron (Fe), the most abundant metal in the atmosphere. The aim of the review was to ...
A male germ cell assay and supporting somatic cells: its application for the detection of phase specificity of genotoxins in vitro [0.03%]
一种雄性生殖细胞试验及其支持的体细胞的应用：在体外检测致突变物的作用阶段特异性
Khaled Habas,Martin H Brinkworth,Diana Anderson
Khaled Habas
Male germ stem cells are responsible for transmission of genetic information to the next generation. Some chemicals exert a negative impact on male germ cells, either directly, or indirectly affecting them through their action on somatic ce...
The complex puzzle of dietary silver nanoparticles, mucus and microbiota in the gut [0.03%]
复杂而又复杂的膳食银纳米颗粒、粘液和肠道微生物群谜题
Yuqiang Bi,Andrew K Marcus,Hervé Robert et al.
Yuqiang Bi et al.
Hundreds of consumer and commercial products containing silver nanoparticles (AgNPs) are currently used in food, personal-care products, pharmaceutical, and many other applications. Human exposure to AgNPs includes oral intake, inhalation, ...
Potential adverse health effects of ingested micro- and nanoplastics on humans. Lessons learned from in vivo and in vitro mammalian models [0.03%]
微塑料和纳米塑料的潜在健康效应及动物模型的启示作用
Laura Rubio,Ricard Marcos,Alba Hernández
Laura Rubio
In recent years, increasing global attention has focused on "microplastics" (MPs) and "nanoplastics" (NPs) resulting in many studies on the effects of these compounds on ecological and environmental aspects. These tiny particles (
Concordance between sites of tumor development in humans and in experimental animals for 111 agents that are carcinogenic to humans [0.03%]
111种人类致癌物在人和实验动物中诱发肿瘤部位一致性分析
Daniel Krewski,Jerry M Rice,Michael Bird et al.
Daniel Krewski et al.
Since the inception of the IARC Monographs Programme in the early 1970s, this Programme has developed 119 Monograph Volumes on more than 1000 agents for which there exists some evidence of cancer risk to humans. Of these, 120 agents were fo...
Genetic toxicity assessment using liver cell models: past, present, and future [0.03%]
遗传毒性评估的肝细胞模型：过去、现在和未来
Xiaoqing Guo,Ji-Eun Seo,Xilin Li et al.
Xiaoqing Guo et al.
Genotoxic compounds may be detoxified to non-genotoxic metabolites while many pro-carcinogens require metabolic activation to exert their genotoxicity in vivo. Standard genotoxicity assays were developed and utilized for risk assessment for...
Properties, toxicity and current applications of the biolarvicide spinosad [0.03%]
spinosad 苏云金芽孢杆菌杀虫剂的特性、毒性及其当前应用研究进展
Vanessa Santana Vieira Santos,Boscolli Barbosa Pereira
Vanessa Santana Vieira Santos
Characterized as a highly valuable bioactive natural product, spinosad is a pesticide with a complex chemical structure, composed of spinosyn A and D, molecules synthesized by the actinomycete Saccharopolyspora spinosa. The larvicidal activ...