Jessica H Hartman,Samuel J Widmayer,Christina M Bergemann et al.
Jessica H Hartman et al.
Caenorhabditis elegans has emerged as a major model in biomedical and environmental toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been published, and this species has now been adopted by investigators in acad...
Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress [0.03%]
姜黄素对抗镉引起的毒性及氧化应激的潜在保护作用
Jae Hyeon Park,Byung Mu Lee,Hyung Sik Kim
Jae Hyeon Park
Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties. Evidence indicates that curcumin might protect against h...
Ethylene oxide review: characterization of total exposure via endogenous and exogenous pathways and their implications to risk assessment and risk management [0.03%]
环氧乙烷评价：内暴露和外暴露特征化及其对风险评估与风险管理的意义
C R Kirman,A A Li,P J Sheehan et al.
C R Kirman et al.
This review is intended to provide risk assessors and risk managers with a better understanding of issues associated with total exposures of human populations to ethylene oxide from endogenous and exogenous pathways. Biomonitoring of human ...
Good management practices of venomous snakes in captivity to produce biological venom-based medicines: achieving replicability and contributing to pharmaceutical industry [0.03%]
毒蛇规范化饲养取 Venom 制备生物药物：实现可复制性和促进制药工业发展的措施
Lucilene Santos,Cristiano Oliveira,Barbara Marques Vasconcelos et al.
Lucilene Santos et al.
One of the factors responsible for lack of reproducible findings may be attributed to the raw material used. To date, there are no apparent studies examining reproducibility using venoms for the development of new toxin-based drugs with res...
Kristina Shkirkova,Krista Lamorie-Foote,Michelle Connor et al.
Kristina Shkirkova et al.
Fine and ultra-fine particulate matter (PM) are major constituents of urban air pollution and recognized risk factors for cardiovascular diseases. This review examined the effects of PM exposure on vascular tissue. Specific mechanisms by wh...
Atmospheric fine particulate matter and epithelial mesenchymal transition in pulmonary cells: state of the art and critical review of the in vitro studies [0.03%]
大气细颗粒物与肺细胞的上皮-间充质转化：综述及体外研究的批判性分析
Margaux Cochard,Frédéric Ledoux,Yann Landkocz
Margaux Cochard
Exposure to fine particulate matter (PM2.5) has been associated with several diseases including asthma, chronic obstructive pulmonary disease (COPD) and lung cancer. Mechanisms such as oxidative stress and inflammation are well-documented a...
Per- and polyfluoroalkyl substances and male reproductive health: a systematic review of the epidemiological evidence [0.03%]
全氟和多氟烷基物质与男性生殖健康：流行病学证据的系统回顾
Kajsa Ugelvig Petersen,Josefine Rahbæk Larsen,Laura Deen et al.
Kajsa Ugelvig Petersen et al.
Exposure to environmental pollutants may produce impairment of male reproductive health. The epidemiological literature evaluating potential consequences of human exposure to per- and polyfluoroalkyl substances (PFAS) has grown in recent ye...
Targeting gap junctional intercellular communication by hepatocarcinogenic compounds [0.03%]
致癌化合物 targeting gap junctional intercellular 通讯的作用机制研究
Kaat Leroy,Alanah Pieters,Andrés Tabernilla et al.
Kaat Leroy et al.
Gap junctions in liver, as in other organs, play a critical role in tissue homeostasis. Inherently, these cellular constituents are major targets for systemic toxicity and diseases, including cancer. This review provides an overview of chem...
Low toxicity and high efficacy in use of novel approaches to control Aedes aegypti [0.03%]
新型控蚊手段对埃及伊蚊的高效低毒作用
Vanessa Santana Vieira Santos,Boscolli Barbosa Pereira
Vanessa Santana Vieira Santos
Arthropod-borne viruses are a group of etiologic agents accounting for different incapacitating diseases that progress to severe and lethal forms in animal and human targets consequently representing a significant burden on public health an...
Samuel M Cohen,Yan Zhongyu,James S Bus
Samuel M Cohen
Mouse lung is a common site for chemical tumorigenicity, but the relevance to human risk remains debated. Long-term bioassays need to be assessed for appropriateness of the dose, neither exceeding Maximum Tolerated Dose (MTD) nor Kineticall...