LncRNA SNHG20 is associated with clinical progression and enhances cell migration and invasion in osteosarcoma [0.03%]
长链非编码RNA SNHG20与骨肉瘤的临床病程相关并促进骨肉瘤细胞迁移和侵袭能力
Jitong Zhang,Chaojie Ju,Wei Zhang et al.
Jitong Zhang et al.
SNHG20 is a novel lncRNA which has been showed to be overexpressed and functions as oncogenic lncRNA in several types of human cancer. The role of SNHG20 in osteosarcoma is still unknown. The purpose of our study was to identify the clinica...
Alysia Mandato,Yuh-Cherng Chai
Alysia Mandato
Mycobacterium tuberculosis is the causative agent of many strains of tuberculosis, as it is composed of an impenetrable, complex cell wall. The proteins active in the synthesis of the cell wall are mycolyl transferase antigens 85A, 85B, and...
Amit Singh,Avadhesha Surolia
Amit Singh
Alternate splicing of transcripts upon Mycobacterium tuberculosis infection impacts the expression of functional protein domains [0.03%]
结核分枝杆菌感染时转录本的可变剪接影响功能蛋白结构域的表达
Haroon Kalam,Kartikeya Singh,Komal Chauhan et al.
Haroon Kalam et al.
Previously, we reported that infection of human macrophages with Mycobacterium tuberculosis (Mtb) results in massive alterations in the pattern of RNA splicing in the host. The finding gained significance since alternate spliced variants of...
PlncRNA-1 is overexpressed in retinoblastoma and regulates retinoblastoma cell proliferation and motility through modulating CBR3 [0.03%]
PLNCRCRNA-1在视网膜母细胞瘤中的表达及其通过调控CBR3影响增殖和运动能力
Shuna Wang,Jianwei Liu,Yang Yang et al.
Shuna Wang et al.
PlncRNA-1 has been suggested to function as an oncogenic role in prostate cancer, colorectal cancer, hepatocellular carcinoma, esophageal squamous cell carcinoma, and gastric cancer. The expression pattern of PlncRNA-1 in retinoblastoma rem...
Metabolomic study for essential hypertension patients based on dried blood spot mass spectrometry approach [0.03%]
基于干燥血点质谱法的高血压代谢组学研究
Qianru Bai,Baohua Peng,Xue Wu et al.
Qianru Bai et al.
Hypertension is an increasingly serious public-health challenge worldwide. The traditional blood pressure measurement method could easily and reliably detect blood pressure. However, the delayed symptom onset may influence the screening of ...
Elucidating the role of (p)ppGpp in mycobacterial persistence against antibiotics [0.03%]
揭示(p)ppGpp在分枝杆菌抗生素耐药性持留状态中的作用
Ashima Bhaskar,Cyntia De Piano,Ekaterina Gelman et al.
Ashima Bhaskar et al.
Bacterial persistence, the ability of bacteria to survive high concentrations of antibiotics for extended periods of time, is an important contributing factor to therapy failure and development of chronic and recurrent infections. Several r...
Mass spectrometry-based proteomic analysis reveals the interacting partners of lipin1 [0.03%]
基于质谱的蛋白质组分析揭示了脂联蛋白1的相互作用伴侣
Jian Wang,Song Wang,Chongjia Yan et al.
Jian Wang et al.
As a lipin family founding member, lipin1 exerts dual functions as a phosphatidate phosphatase enzyme and/or a co-transcriptional regulator in lipid metabolism. In fact, it is also involved in many other cell processes. In this study, we ut...
Heat shock protein 47 as indispensible participant in liver fibrosis: Possible protective effect of lactoferrin [0.03%]
热休克蛋白47作为肝纤维化中的不可或缺参与因子：乳铁蛋白可能的保护作用
Fatma H Rizk,Naglaa I Sarhan,Nema A Soliman et al.
Fatma H Rizk et al.
Lactoferrin (LF) was previously suggested to have a protective effect against liver fibrosis by preventing hepatic stellate cells (HSCs) activation. The effect of LF on heat shock protein 47 (HSP47) has not yet been studied so this study wa...
The Neurovascular Protective Effect of S14G-Humanin in a Murine MCAO Model and Brain Endothelial Cells [0.03%]
S14G-Humanin对小鼠MCAO模型和脑内皮细胞的神经血管保护作用
Tao Peng,Wencui Wan,Jingtao Wang et al.
Tao Peng et al.
Endothelial dysfunction is fundamental to ischemic stroke and brain injury. The humanin analogue S14G-humanin (HNG) has been shown to be a cytoprotective derivative. In this study, we investigated the neuroprotective effects of HNG in vivo ...