Erin Diane Lewis,Simin Nikbin Meydani,Dayong Wu
Erin Diane Lewis
Vitamin E, a potent lipid-soluble antioxidant, found in higher concentration in immune cells compared to other cells in blood, is one of the most effective nutrients known to modulate immune function. Vitamin E deficiency has been demonstra...
Functional and structural characterization of a novel catechol-O-methyltransferase from Schizosaccharomyces pombe [0.03%]
模式古菌Schizosaccharomyces pombe的一种新型儿茶酚O-甲基转移酶的职能和结构特征分析
Qing Wang,Maikun Teng,Xu Li
Qing Wang
Catechol-O-methyltransferase (COMT1 ) catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to various catechol substrates. COMTs play vital roles in physiological processes in animals, plants, and fungi, as well as bacte...
Focally amplified lncRNA on chromosome 1 regulates apoptosis of esophageal cancer cells via DRP1 and mitochondrial dynamics [0.03%]
染色体1上 focally 放大的长链非编码 RNA通过DRP1 和线粒体动力学调节食管癌细胞的凋亡
Tao Liu,Zhi Wang,Riqiang Zhou et al.
Tao Liu et al.
Long noncoding RNAs (lncRNAs), a family of noncoding RNA transcripts with a length of
A method for the gross analysis of global protein acylation by gas-liquid chromatography [0.03%]
一种通过气相色谱法对全球蛋白质酰基化进行粗略分析的方法
Fatemeh Mohammadzadeh,Vahid Hosseini,Amir Mehdizadeh et al.
Fatemeh Mohammadzadeh et al.
Protein acylation is a posttranslational modification in which an amino acid residue of a protein is acylated by a fatty acid. This process plays a key role in regulating proteomic function. Studies of protein acylation have relied on the d...
IL-17A-mediated ERK1/2/p65 signaling pathway is associated with cell apoptosis after non-alcoholic steatohepatitis [0.03%]
IL-17A介导的ERK1/2/p65信号通路与非酒精性steatohepatitis细胞凋亡相关
Ya-Jie Pan,Xing Ren,Ying-Ying Zhang et al.
Ya-Jie Pan et al.
Interleukin (IL)-17A is pro-inflammatory cytokine which has been identified as a noninvasive marker of the pathogenesis of non-alcoholic steatohepatitis (NASH). However, the underlying role of IL-17A in NASH progression remains unclear. Thi...
Ischemic preconditioning improved renal ischemia/reperfusion injury and hyperglycemia [0.03%]
缺血预处理改善肾缺血再灌注损伤和高血糖症
Jian-Ri Li,Yen-Chuan Ou,Chih-Cheng Wu et al.
Jian-Ri Li et al.
Renal ischemia/reperfusion (I/R) is an alternation of renal hemodynamics, which results in diverse postischemic responses and eventually acute kidney injury. Although renal ischemic preconditioning (IPC) is known to protect the kidney from ...
Synergistic Antifungal Activity of Isoquercitrin: Apoptosis and Membrane Permeabilization Related to Reactive Oxygen Species in Candida albicans [0.03%]
异槲皮素的协同抗真菌活性：与白色念珠菌中活性氧相关的细胞凋亡和膜通透性增强
Suhyun Kim,Eun-Rhan Woo,Dong Gun Lee
Suhyun Kim
Isoquercitrin (ISO), one of phytochemical isolated from aerial parts of Aster yomena, has been reported to have antifungal activity. However, the synergistic effect and the mechanism of ISO in combination with conventional antifungal agents...
Diagnostic and prognostic role of serum miR-20b, miR-17-3p, HOTAIR, and MALAT1 in diabetic retinopathy [0.03%]
糖尿病视网膜病变血清miR-20b、miR-17-3p、HOTAIR和MALAT1的诊断及预后价值
Olfat G Shaker,Omayma O Abdelaleem,Rania H Mahmoud et al.
Olfat G Shaker et al.
Noncoding RNAs are emerging biomarkers for many diseases including diabetic retinopathy (DR). This study aimed to measure the expression levels of serum miR-20b, miR-17-3p, HOTAIR, and MALAT1 in DR patients. A total of 80 patients diagnosed...
Lung inflammation and disease: A perspective on microbial homeostasis and metabolism [0.03%]
肺部炎症和疾病：关于微生物稳态和代谢的视角
Roberto Mendez,Sulagna Banerjee,Sanjoy K Bhattacharya et al.
Roberto Mendez et al.
It is now well appreciated that the human microbiome plays a significant role in a number of processes in the body, significantly affecting its metabolic, inflammatory, and immune homeostasis. Recent research has revealed that almost every ...
Investigations on the mechanism of progesterone in inhibiting endometrial cancer cell cycle and viability via regulation of long noncoding RNA NEAT1/microRNA-146b-5p mediated Wnt/β-catenin signaling [0.03%]
通过长链非编码RNA NEAT1/miR-146b-5p介导的Wnt/β-catenin信号通路调控 progesterone 抑制子宫内膜癌细胞周期和活力机制的研究
Xiaohui Huang,Rui Zhong,Xiukui He et al.
Xiaohui Huang et al.
Progesterone is often used to protect the endometrium and prevent endometrial cancer. An intensive study on its molecular mechanism in endometrial cancer would contribute to the development of more promising therapies. Relevant lncRNAs and ...