The IUBMB Focused Meeting on Aminoacyl-tRNA Synthetases 2023 [0.03%]
2023年国际酶与代谢生物化学学会（IUBMB）氨酰-tRNA合成酶专题会议
Patrick O&#x;Donoghue,Ilka U Heinemann
Patrick O&#x;Donoghue
By ligating amino acids to their cognate transfer RNAs (tRNAs), the aminoacyl-tRNA synthetases (AARSs) establish the genetic code in all living cells. This special issue of IUBMB Life is dedicated to the IUBMB Focused Meeting on AARSs in 20...
Editorial
IUBMB life. 2025 Jul;77(7):e70041. DOI:10.1002/iub.70041 2025
MYC-Mediated Osseous Regeneration via BMSCs/PRP/β-TCP/PCL Bioprinted Constructs: Rapid Defect Rehabilitation and Preliminary Clinical Efficacy Evaluation [0.03%]
MYC介导的骨再生：基于BMSCs/PRP/β-TCP/PCL生物打印构建体的快速缺陷修复及初步临床疗效评估研究
Dinghao Luo,Zhaoyang Ran,Junxiang Wu et al.
Dinghao Luo et al.
Bone defects present significant clinical challenges due to their morphological heterogeneity and structural complexity, necessitating regenerative strategies that integrate structural adaptability, biomechanical stability, and osteogenic p...
Deacetylase Inhibitor Trichostatin A Promotes the Proliferation of Epithelial Cells and Suppresses Glycolytic Activity of Fibroblasts in the Kidney [0.03%]
去乙酰化酶抑制剂曲古抑菌素A促进肾上皮细胞增殖并抑制成纤维细胞糖酵解活性
Marina I Buyan,Irina B Pevzner,Andrey I Buyan et al.
Marina I Buyan et al.
Undesirable tissue fibroblast activation after injury is still an unresolved problem for many organs, including the kidney. Kidney fibroblasts and tubular epithelial cells demonstrate significant differences in gene expression profiles, inc...
Establishment of Initiated Cell Line Derived From NIH3T3 Fibroblasts [0.03%]
由NIH3T3成纤维细胞诱导而来的细胞系的建立
Myeong-Han Ro,Taehyun Park,SungHee Hwang et al.
Myeong-Han Ro et al.
Autophagy plays contrasting roles depending on the stage of cellular transformation. However, although advanced tumor cell models are abundant, cell lines at the initiation stage of transformation are very limited. Therefore, the developmen...
A New Treatment Strategy for Lung Cancer With HDAC and Wnt/β-Catenin Pathway Inhibitors [0.03%]
用于肺癌的新治疗策略——组蛋白去乙酰化酶和Wnt/β-catenin通路抑制剂
Elif Erturk,Oguzhan Akgun,Yaren Yildiz et al.
Elif Erturk et al.
Lung cancer is a type of cancer with high morbidity and mortality rates worldwide. The overall survival rate of lung cancer patients is low due to a lack of therapeutic options. Recently, the combination of histone deacetylase (HDAC) inhibi...
Underlining the Molecular Mechanism of Nonalcoholic Fatty Liver Disease and Coronary Artery Disease in Lipid Metabolism by Combining Multiple Sets of Data Sets [0.03%]
通过联合多种数据集阐释脂代谢在非酒精性脂肪肝与冠心病分子机制中的作用
Wei Zheng,Shouhao Wang,Huafang Wang et al.
Wei Zheng et al.
Nonalcoholic fatty liver disease (NAFLD) is closely associated with coronary artery disease (CAD); however, their shared genetic traits and molecular mechanisms in lipid metabolism remain unclear. In this study, we identified that the diffe...
SPP1 Regulates SASP via the p53 Signaling Pathway to Affect ALI Progression [0.03%]
SPP1通过p53信号通路调节衰老相关分泌表型以影响ALI进程
Congcong Yuan,Shilong Zhao,Wentao Ma et al.
Congcong Yuan et al.
Acute lung injury (ALI) is a condition with acute respiratory failure caused by various factors, characterized by severe hypoxemia and diffuse alveolar damage, involving multiple cytokines and signaling pathways. This study investigates the...
Fungi and Myxomycetes of the Tehuacán-Cuicatlán Biosphere Reserve, Mexico: A Comprehensive Review and Future Perspectives [0.03%]
墨西哥特瓦坎-库里亚坦生物圈保护区地衣和黏菌的研究综述及未来展望
Julio Mena-Portales,Yordanis Pérez-Llano,Marco Antonio Vásquez-Dávila et al.
Julio Mena-Portales et al.
The Tehuacán-Cuicatlán Biosphere Reserve in Mexico, spanning approximately 10,000 km2, is crucial for conserving arid and semi-arid ecosystems, as it hosts unique endemic species and complex ecological interactions. Despite their environm...
Single-Cell Profiling of the Microenvironment in High-Risk Neuroblastoma [0.03%]
高危神经母细胞瘤微环境的单细胞测序分析
Yuxuan Xu,Jinsheng Ding,Zhenyu Shi et al.
Yuxuan Xu et al.
Although tumor biology and treatment of neuroblastoma (NB) have substantially advanced, the clinical outcomes of patients with high-risk NB (HR-NB) still remain unsatisfactory. Increasing evidence suggests that targeting the tumor microenvi...
Modulation of PPAR-α and PPAR-γ Influences Cardiomyocyte Growth and Cardiac Remodeling [0.03%]
PPAR-α和PPAR-γ的调节影响心肌细胞增殖及心脏重塑
Qinkao Xuan,Jin Li,Zexiong Feng et al.
Qinkao Xuan et al.
Peroxisome proliferator-activated receptors (PPARs), particularly PPAR-α and PPAR-γ, are key regulators of cardiac energy metabolism and have been implicated in cardiac remodeling. However, their roles in cardiomyocyte proliferation and h...