Modulation of Osteogenic Differentiation by CYBB in Osteoporotic Models [0.03%]
CYBB调节骨形成在骨质疏松症模型中的作用
Zhaodong Wang,Chen Xu,Yajun Liu et al.
Zhaodong Wang et al.
Osteoporosis (OP) is a prevalent systemic skeletal disease characterized by increased bone fragility and fracture risk. Identifying factors that influence osteogenic differentiation in OP is crucial. We screened genes associated with OP fro...
Correction to "Upstream Transcription Factor 1 Suppresses Laryngeal Squamous Cell Carcinoma Progression Through Transcriptional Activation of Junctional Adhesion Molecule 3" [0.03%]
“上游 transcription factor 1通过转录激活连接粘附分子 3抑制喉鳞状细胞癌进展”的勘误函
Published Erratum
IUBMB life. 2025 May;77(5):e70021. DOI:10.1002/iub.70021 2025
Therapeutic Potential of Translational Readthrough at Disease-Associated Premature Termination Codons From Tumor Suppressor Genes [0.03%]
肿瘤抑制基因疾病相关提前终止密码子的转录读码-through治疗潜力
Leire Torices,Caroline E Nunes-Xavier,Rafael Pulido
Leire Torices
Tumor suppressor genes are frequently targeted by mutations introducing premature termination codons (PTC) in the protein coding sequence, both in sporadic cancers and in the germline of patients with cancer predisposition syndromes. These ...
Synergistic Effects of Epirubicin-Vorinostat-Pimozide Drug Cocktail on Proliferation, Stemness, Invasiveness, and Fatty Acid Metabolism in Breast Cancer Cells [0.03%]
表柔比星-伏立诺他-匹莫齐德药物联合治疗对乳腺癌细胞增殖、干性、侵袭性和脂肪酸代谢的协同作用
Thirukumaran Kandasamy,Shilpi Sarkar,Azar Zochedh et al.
Thirukumaran Kandasamy et al.
Chemotherapeutic treatments for breast cancer are often associated with severe toxicity due to the requirement of high concentrations of the drugs for efficacy. The combination of chemotherapy drugs along with repurposed drugs offers a prom...
Ischemic preconditioning attenuates ischemia/reperfusion-induced acute kidney injury dependent on mitochondrial protease CLPP [0.03%]
缺血预处理通过线粒体蛋白酶CLPP依赖性途径减轻再灌注急性肾损伤
Wenjia Xie,Lingqi Gao,Xinyan Gu et al.
Wenjia Xie et al.
Ischemic preconditioning (IPC) is a phenomenon in which brief periods of ischemia trigger protective mechanisms that alleviate subsequent ischemia-reperfusion injury (IRI), although the precise protective mechanism remains unclear. This stu...
Yeast models for Charcot-Marie-Tooth disease-causing aminoacyl-tRNA synthetase alleles reveal the cellular basis of disease [0.03%]
酵母模型对于揭示Charcot-Marie-Tooth疾病致病的氨基酸-tRNA合成酶等位基因的细胞基础的应用
Maria Mahmood,Emma Little,Nicole Girard et al.
Maria Mahmood et al.
Charcot-Marie-Tooth disease (CMT) is a genetically diverse hereditary disorder that affects the motor and sensory nerves, impacting about 1 in 2500 people. It can be inherited through autosomal dominant (AD), autosomal recessive (AR), or X-...
Downregulation of KLF9 alleviates tubulointerstitial fibrosis by modulating FABP4-mediated lipid accumulation [0.03%]
KLF9的下调通过调节FABP4介导的脂质积累来缓解管间质纤维化
Lin Zhang,Xin-Yu Wang,Ting Tian et al.
Lin Zhang et al.
Tubulointerstitial fibrosis (TIF) is a significant determinant in the pathogenesis of chronic kidney disease (CKD) and is commonly concurrent with lipid infiltration in the renal tubules. Nonetheless, the precise regulatory mechanism of thi...
OTUB1 facilitates lipid accumulation in oxLDL-induced THP-1 macrophages by stabilizing scavenger receptor-A [0.03%]
OTUB1通过稳定清道夫受体A促进oxLDL诱导的THP-1巨噬细胞脂质积聚
Xianwei Huang,Yixuan Liu,Xiong Liu et al.
Xianwei Huang et al.
The formation of foam cells triggered by excessive lipid accumulation within macrophages is a hallmark of atherosclerosis development. Scavenger receptor-A (SR-A) is a key regulator of lipid uptake by macrophages during oxidized low-density...
Conventional and innovative approaches to black fungi control for stone heritage preservation [0.03%]
用于石质文化遗产保护的防治黑真菌的传统方法和创新方法
Domenico Celi,Massimiliano Marvasi,Brunella Perito
Domenico Celi
Black Meristematic Fungi (BMF) are characterized by a thick melanized cell wall and an isodiametric cellular expansion. BMF represent one of the most damaging groups of microorganisms causing the deterioration of outdoor exposed stone monum...
Upstream transcription factor 1 suppresses laryngeal squamous cell carcinoma progression through transcriptional activation of junctional adhesion molecule 3 [0.03%]
上游转录因子1通过粘附分子3的转录激活抑制喉鳞状细胞癌的发展
Yue Jia,Jiaojiao Liu,Yichen Lou et al.
Yue Jia et al.
Laryngeal squamous cell carcinoma (LSCC) exhibits aggressive growth, frequent recurrence, and a notable resistance to existing treatments. Building upon prior discoveries that identified junctional adhesion molecule 3 (JAM3) as a critical t...