Atorvastatin-Loaded Mineralized Vaccine Reprograms Endosomal Trafficking to Amplify STING-Driven Cancer Immunotherapy [0.03%]
阿托伐他汀载药矿化疫苗重新编程内吞小体运输以增强STING驱动的癌症免疫治疗
Yuhan Yang,Wei Long,Xiangyu Pei et al.
Yuhan Yang et al.
Dendritic cell (DC)-targeted nanovaccines offer great promise for cancer immunotherapy but are severely limited by premature lysosomal degradation of antigens, which reduces cross-presentation efficacy. Here, we report a facile yet effectiv...
Min Tan,Xueyan Zhao,Zhibin Zhao et al.
Min Tan et al.
Efficiently manipulating charge transport at the molecular level is critical to developing multifunctional and responsive molecular electronic devices. Here, we report the first electroresponsive tristate switch in a supramolecular circuit,...
Monodisperse Regulation of Self-Assembled Monolayer Via Dipole Molecules for Efficient Perovskite Solar Cells [0.03%]
基于偶极分子自组装单分子层的单分散调节实现高效钙钛矿太阳能电池
Zhinan Zhang,Yinghao Xu,Sifan Chen et al.
Zhinan Zhang et al.
The application of self-assembled monolayers (SAMs) significantly drives the enhancement in the efficiency of perovskite solar cell (PSC). However, the transition mechanism of SAM molecules from colloidal solutions to films remains unclear....
In Situ Sulfur Modification Enables Electrochemical Selective Deuterated Thiol-Yne Reactions [0.03%]
原位硫修饰使电化学选择性脱硫-炔反应成为可能
Liyuan Lan,Ying Gao,Cuibo Liu et al.
Liyuan Lan et al.
The deuterated thiol-yne reaction using D2O represents an attractive strategy for simultaneously introducing pharmaceutically relevant C(sp2)─D bonds and vinyl sulfide motifs. However, achieving high deuterium (D) incorporation remains a s...
The Design of Interfacial Organic-Riched Phase by Molecular Interlocking for Stable Zn Anodes [0.03%]
通过分子交联设计界面富有机物相以获得稳定锌负极
Min Yang,Yanan Zhang,Qingjie Li et al.
Min Yang et al.
Rechargeable aqueous zinc-ion batteries (ZIBs) are promising energy storage devices due to their high safety and environmental friendliness. However, they suffer from some issues in Zn anodes, including dendrites, hydrogen evolution reactio...
1,4-Dearomatization of Pyridines and Quinolines Enabled by the Carbodication Lewis Acid [0.03%]
路易斯酸活化碳自由基正锂化实现哒嗪和喹啉的去芳香化反应
Xiaofeng Huang,Qiu Shi,Guoyin Lai et al.
Xiaofeng Huang et al.
1,4-Dihydropyridines (DHPs) are valuable compounds in medicinal chemistry and organic synthesis. The most straightforward pathway for preparing 1,4-DHPs is the direct 1,4-reduction of pyridines and quinolines. However, existing strategies a...
Scalable Synthesis of Stable Hydrogen-Bonded Organic Framework for Efficient Hexafluoroethane Purification [0.03%]
一种用于高效六氟乙烷分离的稳定氢键有机框架材料的可扩展合成方法研究
Zhenyu Ji,Yunzhe Zhou,Rajamani Krishna et al.
Zhenyu Ji et al.
Developing stable, efficient and easily scalably-synthesized adsorbents for removal of hydrofluoroethanes to obtain high purity hexafluoroethane (C2F6) is of great importance to the electronics industry. Herein, we report a hydrogen-bonded ...
Nickel-Catalyzed Regioselective and Enantioselective Olefin-Aldehyde Cross-Couplings Toward Acyloin Isosteres [0.03%]
镍催化烯烃-醛的区域选择性和对映选择性交叉偶联反应制备羟基酸异构体类化合物
Mingshuai Zhang,Meihong Luo,Gang Zhao et al.
Mingshuai Zhang et al.
Bioisosteric replacement of ketones with three-dimensional (3D) motifs, such as oxetanes and azetidines, has emerged as a powerful tool in molecular design, enabling access to novel chemical space with improved pharmacokinetic profiles. How...
Carbon Dots-Induced Hydrogen-Bonding Traps in RHO Zeolite: Mechanistic Insights and Superior Flue Gas Separation Performance [0.03%]
碳点在RHO分子筛中诱导形成氢键陷阱：机理研究及烟气分离性能提升
Yining Yang,Yida Zhou,Siyu Zong et al.
Yining Yang et al.
Zeolites stand out as promising materials for flue gas separation, however, it poses a significant challenge to conduct pore interior modifications to improve the separation performance. Herein, we present a novel strategy for constructing ...
Intercalation Chemistry Awakens Transition Metal Hydroxide for Boosted and Sustained Electrocatalytic Sulfion Oxidation [0.03%]
插层化学激活过渡金属氢氧化物实现增强且持久的电催化磺酰化氧化反应
Fengli Li,Wai Kwong Ng,Wei Qiao et al.
Fengli Li et al.
Electrocatalytic sulfion oxidation reaction (SOR) is a sustainable approach to treat sulfion-rich sewage for S recovery. Transition metal hydroxide (TMOH), utilized in various electrocatalysis, yet is clumsy in SOR due to overstrong adsorpt...