Tu Zeng,Shiqing Huang,Yingjian Gong et al.
Tu Zeng et al.
Divergent access to complex molecular skeletons from the same set of readily available raw materials has been a primary goal of chemical synthesis, owing to their widespread application in drug research. In this study, a copper-catalyzed in...
Cage Engineering in Anion-Pillared MOFs for Benchmark One-Step C2H4 Purification from Ternary C2H2/CO2/C2H4 Mixtures [0.03%]
通过MOF中阴离子支柱的笼工程实现一步法净化三元C2H2/CO2/C2H4混合物中的C2H4
Lingyao Wang,Huirong Chen,Chengye Lou et al.
Lingyao Wang et al.
One-step purification of ethylene (C2H4) from the ternary mixtures of acetylene/carbon dioxide/ethylene (C2H2/CO2/C2H4) is a critical industrial challenge due to their similar physical and chemical properties. Herein, we reported a cage eng...
Mungo Frost,Kilian Abraham,Alexander F Goncharov et al.
Mungo Frost et al.
Gold is an unreactive metal and its chemical interactions with hydrogen have only recently been explored. Here, we report the formation of gold hydride above 40 GPa and 2200 K in X-ray free electron laser heated diamond anvil cells using va...
Triadic Electrophilic Centers Specifically Bind to SMO Transmembrane Domain to Inhibit the Hedgehog Pathway [0.03%]
三价亲电子中心特异性结合于SMO跨膜结构域以抑制Hh信号通路
Fei Cai,Jin Zhang,Hui Li et al.
Fei Cai et al.
Designing drugs to target overexpressed membrane protein smoothened (SMO) to selectively inhibit the Hedgehog signaling pathway represents a promising approach to achieving effective chemotherapy. Currently, only three organic small molecul...
Anion-Regulated Deposition-Dissolution Chemistry in Acidic Aqueous Indium─MnO2 Batteries [0.03%]
酸性水系铟-二氧化锰电池中的阴离子调控沉积溶解化学反应
Yuwei Sun,Chen Wang,Ling Gao et al.
Yuwei Sun et al.
Acidic aqueous metal─MnO2 rechargeable batteries enable high-capacity energy storage via a two-electron MnO2/Mn2+ redox chemistry but suffer from severe anode corrosion and poor reversibility in acidic environments. Here, we report an acid...
Discharge Rate-Driven Li2O2 Growth Exhibits Unconventional Morphology Trends in Solid-State Li-O2 Batteries [0.03%]
固态锂氧电池中放电速率驱动的Li2O2生长表现出非常规形貌趋势
Xiaozhou Huang,Matthew Li,Yanan Gao et al.
Xiaozhou Huang et al.
Solid-state lithium oxygen batteries (LOBs) are known for their enhanced safety, higher electrochemical stability, and improved energy density compared to liquid-state LOBs. However, the investigation of solid-state LOBs is limited with lit...
Tailoring a Fast Ion-Conducting Substrate with Competitive Adsorption for Dendrite-Free Lithium/Potassium Metal Batteries [0.03%]
一种快速离子导体基底用于锂/钾金属电池实现无枝晶沉积成长
Jinlong Jiang,Jinshuang Liu,Xiaoyang Zheng et al.
Jinlong Jiang et al.
The desolvation behavior of Li+ is widely regarded as primarily governed by the electrolyte composition, while the dynamic decoupling mechanism between the electrode interface and solvation structure has received limited attention. Herein, ...
Intramolecular Lithiation-Borylation for the Stereoselective Synthesis of Cyclopentyl and Cyclobutyl Bis-Boronic Esters [0.03%]
分子内锂化-硼化的立体选择性合成环戊基和环丁基双硼酸酯反应
Christopher J Cope,Margherita Zanini,Malcolm R P George et al.
Christopher J Cope et al.
Saturated carbocycles are common motifs in natural products and pharmaceuticals, and so methods for their construction, particularly with high diastereo- and enantiocontrol, are of high importance. Lithiation-borylation has emerged as power...
Long Range Coherent Energy Transfer in Artificial Multichromophoric Antenna Systems-A Case of Breaking Kasha's Rule [0.03%]
人工多发色团天线系统中的长程相干能量传递-违背卡沙规则的一个特例
Maryam Nazari Haghighi Pashaki,Caroline D Bösch,Florian Garo et al.
Maryam Nazari Haghighi Pashaki et al.
Ultrafast long-range energy transfer with unitary quantum-yield has been studied in a novel family of artificial DNA-guided multichromophoric antenna complexes with phenanthrene moieties as light harvesters. By means of femtosecond transien...
A Chemically Tailorable Multifunctional Protein Platform for Glutamatergic Neuron Targeting in Mouse Brain [0.03%]
一种化学可修饰的多模式蛋白平台用于小鼠脑谷氨酸能神经元靶向
Xiaoti Yang,Shuxin Li,Jing Liu et al.
Xiaoti Yang et al.
Targeting glutamatergic neurons is critical for understanding brain functions and treating neurological disorders linked to glutamate dysregulation. However, existing methods face challenges including low specificity, slow kinetics, poor bl...