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Experimental lung research. 2026;52(1):1. DOI:10.1080/01902148.2026.2707582 2026
The carotid body role in oxygen sensing: Anatomy, neurovascular organization, and structural bases of chemotransduction [0.03%]
颈动脉体在氧气感应中的作用：解剖学、神经血管组织和化学转导的结构基础
Zaki Alsahafi,Ahmaed Baashar
Zaki Alsahafi
Background: The carotid body is a small, highly vascularized organ located at the bifurcation of the common carotid artery and serves as the primary peripheral detector of arterial oxygen tension in mammals. Although its ...
The role of ABHD2 in cigarette smoke-induced skeletal muscle atrophy in chronic obstructive pulmonary disease mice: The mechanism of ABHD2 in skeletal muscle atrophy [0.03%]
ABDH2在香烟烟雾诱导的慢性阻塞性肺疾病小鼠骨骼肌萎缩中的作用：ABDH2介导的肌肉萎缩机制研究
Qingyan Lin,Jun Liu,Han Xie et al.
Qingyan Lin et al.
Background: Chronic obstructive pulmonary disease (COPD) is a major and increasing global health problem that results in progressive airway obstruction. Cigarette smoke (CS) exposure, a major cause for COPD, induces mitochondrial damage, wh...
Mechanistic study on the role of NCSTN in regulating the differentiation of airway epithelial basal cells into ciliated cells following CSE exposure [0.03%]
NCSTN在CSE暴露后调控气道基底细胞分化为纤毛细胞的机制研究
Maohua Lan,Caimei Wang,Yanhui Gu et al.
Maohua Lan et al.
Background: Chronic obstructive pulmonary disease (COPD) ranks as the third leading cause of death worldwide and is primarily caused by cigarette smoke (CS) exposure. A reduction in the number of ciliated cells significantly contributes to ...
The downregulation of RAB10 by miR-574-5p alleviates the inflammatory response in neonatal respiratory distress syndrome [0.03%]
miR-574-5p通过下调RAB10缓解新生儿呼吸窘迫综合征的炎症反应
Yanan Ji,Yangping Zhou,Ludan Deng et al.
Yanan Ji et al.
Aim: The diagnosis of neonatal respiratory distress syndrome NRDS relies on progressive breathing difficulties after birth, abnormal blood oxygen levels, and typical chest X-ray images. However, this diagnostic method has...
Copper homeostasis dysregulation and cuproptosis in respiratory diseases [0.03%]
铜稳态紊乱和铜细胞死亡在呼吸系统疾病中的作用
Yusheng Gao,Xiuping Chen,Yixin Xu
Yusheng Gao
Cuproptosis, a recently identified form of regulated cell death, relies on accumulated copper (Cu) ions and a disrupted mitochondrial respiratory chain. The role of cuproptosis in various diseases, especially respiratory diseases of pulmona...
IL-36G drives sepsis-induced lung injury via NF-κB-dependent activation of the NLRP3 inflammasome in macrophage pyroptosis [0.03%]
白细胞介素36G通过NF-κB依赖的NLRP3炎性小体活化驱动促脓毒症巨噬细胞Pyroptosis的肺损伤
Mingguo Yan,Zhixin Chen,Yuan Song et al.
Mingguo Yan et al.
Background: Sepsis is a critical illness marked by widespread inflammation and failure of multiple organs. Pyroptosis and NLRP3 inflammasome activation play critical roles in sepsis pathogenesis. However, the involvement ...
Targeted delivery of Follistatin-like 1 siRNA via biodegradable nanoparticles attenuates bleomycin-induced pulmonary fibrosis in mice [0.03%]
载有Follistatin-like 1的可生物降解纳米颗粒通过靶向给药来缓解bleomycin诱导的小鼠肺纤维化作用
Xue Li,Maolin Yao,Min Yu et al.
Xue Li et al.
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disorder that often leads to fatal outcomes, characterized by the aberrant proliferation of myofibroblasts and excessive depos...
Inhibitory effects of METTL3 on airway smooth muscle cell proliferation and migration via lncRNA GAS5/miR-29c-3p/VAMP2 axis [0.03%]
METTL3通过lncRNA GAS5/miR-29c-3p/VAMP2轴抑制气道平滑肌细胞增殖和迁移的作用机制研究
Xia Xi,JunYing Guo,ShuXiang Sui et al.
Xia Xi et al.
Objective: Asthma development is significantly influenced by the abnormal proliferation and migration of human airway smooth muscle cells (HASMCs). The aim of this study was to investigate the role and molecular mechanisms of the m6A methyl...
Effect and mechanism of chemokine receptor 1 in airway inflammation in a mouse model of chronic obstructive pulmonary disease [0.03%]
化学引诱素受体1在慢性阻塞性肺疾病小鼠模型气道炎症中的作用及机制研究
Wei Wei,Suzhen Ju,Yanfang Yu et al.
Wei Wei et al.
Objective: We aimed to investigate the role and mechanisms of chemokine receptor 1 (CCR1) in airway inflammation in chronic obstructive pulmonary disease (COPD) mice. ...