Carbon dots for drug delivery: Insights into their potential in nanopharmacology [0.03%]
碳点在药物递送中的应用：其在纳米药理学中的潜力初探
Daniela Iannazzo,Consuelo Celesti,Lucia Cardo et al.
Daniela Iannazzo et al.
Carbon dots (CDs), a remarkable class of novel nanomaterials, have attracted significant attention in the biomedical field owing to their extraordinary chemical, physical, and biological properties. Among their diverse applications, CDs sta...
Gut microbiome and bile acid metabolism in liver disease: Mechanisms, clinical implications, and therapeutic opportunities [0.03%]
肠道菌群和胆汁酸代谢在肝病中的作用：机制、临床意义和治疗机会
Huiping Zhou,Yi Huang,Chen Chen et al.
Huiping Zhou et al.
The intricate interplay between the gut microbiome and bile acid metabolism via the gut-liver axis is fundamental to hepatic homeostasis. Perturbations in this axis are increasingly implicated in the pathogenesis of diverse liver diseases, ...
Links between COVID-19, long COVID, and neurodegeneration: The role of glycosphingolipids [0.03%]
COVID-19、长新冠与神经退行性疾病之间的联系：糖苷鞘脂的作用
Michael Spedding,Johannes Aerts,Steve Alexander et al.
Michael Spedding et al.
Glycosphingolipids (GSLs) play major roles in viral infections by mediating viral entry and egress from cells in lipid rafts; however, GSLs are also important in neurodegenerative diseases. The role of GSLs in acute COVID-19 infection is cr...
Role of solute carrier transporters in the biodistribution and toxicity of chemotherapeutic drugs [0.03%]
溶质载体转运蛋白在化疗药物的组织分布和毒性中的作用
Mike Boeckman,Thomas Drabison,Arthur Germakovski et al.
Mike Boeckman et al.
Our understanding of the solute carrier (SLC) family of transporters has greatly increased in recent years, especially in oncology, and a wealth of information is now available, indicating that certain SLC family members contribute to the c...
The role of polysubstance use in the development, maintenance, and treatment of stimulant use disorders [0.03%]
多物质使用在兴奋剂使用障碍的发展、维持和治疗中的作用
Mia I Rough,Michael A Nader
Mia I Rough
Stimulant use disorders represent a significant public health challenge, with no U.S. Food and Drug Administration (FDA) pharmacotherapies currently available. A growing concern is that stimulant use rarely occurs in isolation. Instead, it ...
Pharmacology and therapeutics of bile acid synthesis and modification enzymes in metabolic diseases [0.03%]
代谢性疾病中的胆汁酸合成和修饰酶的药理学与治疗学
Lili Ding,Lihua Jin,Wendong Huang
Lili Ding
Bile acids (BAs) are mainly synthesized in the liver as end products of cholesterol catabolism through the classic (neutral) and alternative (acidic) pathways. BA synthesis requires a coordinated series of enzymes, in which CYP7A1 catalyzes...
Pharmacological modulation of the blood-brain barrier: Mechanisms, therapeutic strategies, and emerging technologies [0.03%]
药理学调控血脑屏障：机制、治疗策略和新兴技术
Iosif Pediaditakis,Serena Tsakali,Maddie R Lemieux et al.
Iosif Pediaditakis et al.
The blood-brain barrier (BBB) is a specialized vascular interface that safeguards central nervous system homeostasis by tightly regulating molecular exchange between blood and the brain. While essential for neuroprotection, its restrictive ...
Erratum to "Animal models of attention-deficit/hyperactivity disorder: Diversity and validity" [Pharmacological Reviews 78 (2026) 100108] [0.03%]
关于“注意缺陷多动障碍动物模型：多样性与有效性”的勘误[药理学评论78(2026)100108]
Sarah Bou Sader Nehme,Sandra Sánchez-Sarasúa,Mari-Carmen Medrano et al.
Sarah Bou Sader Nehme et al.
Published Erratum
Pharmacological reviews. 2026 Feb 6;78(2):100123. DOI:10.1016/j.pharmr.2026.100123 2026
Erratum to "Edaravone: Advances on cytoprotective effects, pharmacological properties, and mechanisms of action" [Pharmacological Reviews 78 (2025) 100101] [0.03%]
关于“依达拉奉：细胞保护作用、药理特性及机制研究进展”论文的勘误通知书[《药理学评论》78卷(2026)页码100101]
Fatima Dakroub,Bassel Awada,Samar Abdelhady et al.
Fatima Dakroub et al.
Published Erratum
Pharmacological reviews. 2026 Feb 6;78(2):100114. DOI:10.1016/j.pharmr.2026.100114 2026
Preclinical abuse potential testing using behavioral economics and drug self-administration demand-curve analysis: A strategy to improve resolution of drug stratification for regulatory control [0.03%]
使用行为经济学和药物自主给药需求曲线分析进行临床前滥用潜力测试：一种改善监管控制下药物分类分辨率的策略
Matthew L Banks,S Stevens Negus,Neil B Varshneya et al.
Matthew L Banks et al.
New chemical entities (NCEs) that act on the central nervous system are synthesized in pharmaceutical drug development programs for investigational purposes or by clandestine laboratories for illicit purposes. One component in the regulator...